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do males have a surge center?
no, just tonic
(male) what does LH stimulate production of? Where does this product go?
leydig produces testosterone, to circulation or sertoli
(male) what does FSH stimulate production of? what does this product bind with?
sertoli produces e2 and inhibin, androgen binding protein
why is the time between FSH peaks longer than GnRH?
constant - feedback from sertoli inhibin
3 stages in spermatogenesis
proliferative, meiosis, differentiation
formation of new spermatozoa
spermatogenesis
new sperm created in proliferative (mitosis) phase
spermatocytogenesis
change from round spermatid to spermatozoa
spermiogenesis
5 stages of sperm development
spermatogonium, primary/secondary spermatocyte, spermatid, spermatozoa
death of sperm cells due to natural process or trauma
apoptosis
what ensures spermatogenesis process will be ongoing?
stem cell renewal (A goes back after mitosis)
4 phases of spermiogenesis
golgi, cap, acrosomal, maturation
microtubules that pull and elongate sperm during acrosomal stage of spermiogenesis
manchette
sperm released from sertoli cell
spermiation
how long before a deleterious event shows up in ejaculated sperm?
2-4 weeks
how long after a deleterious event until normal sperm is restored?
6-12 weeks
how many stages are in a cycle?
8
how many cycles does a sperm go through to become a spermatozoa?
4.5
how many days does a cycle last in a bull?
13.5
how many days from beginning of process to sperm release?
60
what does the concept of spermatogenic waves mean?
some part of tubule always releasing sperm
do all cycles last the same amount of time?
no
which phase is a deleterious event worse for?
proliferative (mitosis)
what do golgi bodies make during spermiogenesis? what do these become?
proacrosomic granules, become acrosomic vescles
why do we need tight junctions creating a blood/testis barrier?
immune cells attack mitosis sperm
which sperm types are in the basal compartment (mitosis)?
spermatogonia, primary spermatocytes
which sperm are in the adluminal compartment (meiosis)?
primary/secondary spermatocytes, spermatids
what are sertoli cells crucial for regulating?
meiosis
5 structures in the pathway of the sperm
seminiferous tubules, rete tubules, vas efferentia, epididymis, vas deferens
whic hormone causes the vas deferens to contract?
oxytocin
5 functions of the epididymis
maturation, concentration, secretion, transport, storage
what is secreted into the sperm mixture in the epididymis?
energy sources, glycoproteins/lipids/enzymes membrane changes
which species are short ejaculators?
bull, ram
which species is a moderate ejaculator?
stallion
which species is a long ejaculator?
boar
which are the 3 fractions in moderate/long ejaculators?
sperm free, sperm rich, gel
what exactly is in semen?
water, sperm, proteins, inorganic salts, substrates (fructose, inositol, GPC)