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Polygenic traits
traits that are controlled by several allelic pairs, which produces a continuous range of phenotypic variation, with each dominant allele having an additive effect
skin color
eye color
height
etc.
polygenic inheritance
Skin color
results from pigmentation produced in specialized cells in the skin called melanocytes
over 100 genes control skin color
polygenic inheritance
Environmental Influence
many genetic disorders including clef lip, clubfoot, schizophrenia, diabetes, phenylketonuria, and even allergies and cancers are likely controlled by polygenic traits that are subject to environmental influences
Multifactorial trait
a condition that is caused by the interaction of multiple genes and environmental conditions
environmental influence
Codominance
occurs when alleles are equally expressed in a heterozygote
a common example occurs within human blood types
^ AB blood type exists when one allele is for A and the other is for B
Unlike incomplete dominance, the heterozygote does not express a condition at a midpoint between two alleles, but instead expresses both alleles equally
Multiple alleles
occurs when a gene exists with more than two allelic forms; however, one person can still only have two of the possible alleles
ex: human blood types - phenotypes (A, B, AB, O), possible genotypes (IAIA IAi, IBIB IBi, IAIB, ii)
Sex-linked
traits controlled by genes on the sex chromosomes (X or Y)
most sex-linked genes are X-linked (the Y chromosome is much smaller than a typical chromosome)
most genes on the X-chromosome have nothing to do with an individual’s gender
^for example, our ability to perceive color is coded on the X-chromosome
X-linked
alleles on the X chromosome
Y-linked
alleles on the Y chromosome
Genotypes and Phenotypes for perception of color
Genotypes: XBXB, XBXb, XbXb, XBY, XbY
Phenotype: Female with normal vision, carrier female who has normal vision, female who is color blind, male who has normal vision, male who is color blind
Most notable X-linked disorders
Color blindness
Duchenne muscular dystrophy
Fragile X syndrome
Hemophilia