Solid organ transplant tolerance
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Last updated 9:14 PM on 4/12/25
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4 Terms
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Why might solid organ transplants between dizygotic twins be better tolerated?
Because of blood chimerism—shared blood circulation during development.
2
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What is blood chimerism?
It’s the presence of cells from one individual in the blood of another, often from shared circulation during development or prior transplants.
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How can prior organ transplantation affect future transplant tolerance?
It may lead to blood chimerism, which can promote tolerance to future transplants.
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How do donor hematopoietic stem cells help prevent solid organ graft rejection?
They can induce immune tolerance in the recipient, reducing the risk of rejection.
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