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neuron
cell of the nervous system specialized for sending and receiving neural messages
sensory neurons
carry messages from the sensory organs (i.e. eyes, tongue, skin) to spinal cord and brain
motor neurons
carry messages from the brain and spinal cord to muscles and glands
interneurons
located within the brain and spinal cord collect, integrate & retrieve messages from various sources
dendrites
receive chemical messages from other neurons
cell body/soma
collects neural impulses, contains the nucleus, sustains cell functions
axon
transports electrical impulses to other neurons via the terminal branches
axon terminals/terminal branches
convert electrical signals into chemical messages for other neurons
myelin sheath
fatty layer that insulates the axons & speeds up transmission of electrical signals
glia
nervous system cells that perform variety of critical support functions
Action potential
neurons “talk” to each other by firing off electrical impulses
cell membrane
thin fatty “skin” enclosing the neuron
Resting potential
more negatively charged particles inside cell relative to outside
neuron cannot fire action potential in this state
ion channels
allow positively charged sodium ions to enter
Depolarization
Electrical charge across membrane begins to reverse
voltage threshold
critical level to which a neuron’s membrane potential must be depolarized to initiate action potential
Repolarization
potassium channels remain open → flow out of the cell
Refractory period
ensures that action potential is propagated forward during resting potential
synaptic cleft
gap separating neurons
neurotransmitters
chemical messengers that presynaptic neuron sends
receptor
channel in membrane of a neuron that binds neurotransmitters
diffusion
neurotransmitters drift out of synapse
degradation
neurotransmitters are broken down in the synapse
reuptake
neurotransmitters are reabosrbed into the presynaptic terminal brances
excitation
receiving neuron slightly deplorized
inhibition
receiving neuron slightly hyperpolarized
GABA
neurotransmitter that is responsible for downregulation of stress, anxiety, fear
Acetylcholine
Plays key role in autonomic nervous system, which carries commands from brain to glands & organs, regulates cardiac activity
Norepinephrine
Important for “fight or flight response”
regulation of arousal & vigilance
Serotonin
Contributes to regulation of sleep, appetite, mood, and aggression
Dopamine
Involved in movement, planning, and aspects of reward
Endorphins
Promote feelings of pleasure and reduce pain
psychoactive drugs
chemical substances that alter a person’s thoughts, feelings, or behaviors by influencing the activity or neurotransmitters in the nervous system
agonist
enhances action of a neurotransmitter
antagonist
inhibits actions of a neurotransmitter
Nervous system
complex network of nerves (bundles of neurons) that controls & regulates all bodily functions
Central nervous system (CNS)
brain & spinal cord
Peripheral nervous system (PNS)
nerves connecting brain to the rest of your body
Somatic nervous system
carries commands for voluntary movement from CNS to muscles
Autonomic nervous system
carries involuntary commands to organs, blood vessels, & gland
fight-or-flight response
expenditure of energy
Sympathetic nervous system (SNS)
Pupil dilation, increased breathing, heart rate & blood flow to muscles
rest-and-digest
returns body to resting state
Parasympathetic nervous system (PNS)
Controls gland & organs during calm periods, nutrient storage, repair, growth
endocrine system
network of glands (hormone-secreting organs) that work together with CNS and PNS
hormone
blood-borne chemical messengers
adrenal glands
located on top of kidneys, release of adrenaline and cortisol
pituitary gland
The ‘master gland’ that directs other glands and regulates hunger, sexual arousal, growth, sleep (via pineal gland), navigation of social world
oxytocin
Hormone released into bloodstream by pituitary gland which has a key aspect of reproductive systems
spinal cord
Major bundle of nerves connecting brain to rest of the body
spinal reflexes
initiated by spinal cord without involvement of the brain
brainstem
Lowest region of the brain, sits on top of spinal cord
Where spinal nerves & most cranial nerves connect
Regulates vital functions; damage to this area is often lethal
midbrain
transmit info for vision & hearing, orientation towards salient stimuli (tegmentum), movement, motivation & reward, downregulation of pain
medulla
control vital processes like heart rate, blood pressure, reflexes like coughing and swallowing
pons
transmit messages, giving sensory (hearing & taste) and motor cues (balance & coordination) to the body
reticular formation
involved in various physiological functions (arousal, attention, wakefulness)
cerebellum
coordination, balance, precise movements & accurate timing
limbic system
Known as the ‘emotional brain’
hypothalamus
‘interface’ between brain & body, homeostatic regulation: temperature, thirst, hunger, biological rhythms, motivation, reward seeking, fight-or-flight response, directs the autonomic nervous system & endocrine system
thalamus
‘relay station’ for all sensory signals (except smell), alertness & consciousness
amygdala
processing emotional significance of sensory information
psychic blindness
normal vision, but visual stimuli lose their emotional significance
hippocampus
memory, spatial navigation, mental time-travel
basal ganglia
controlling voluntary movement, suppression of unwanted movement, reward & pleasure
cerebral cortex
Outermost and largest part of the human brain
corpus callosum
large bundle of nerve fibers
Frontal lobe
Movement and planning, judgement, decision-making
primary motor cortex
a “map” of the body’s muscles
prefrontal cortex
“personality center”
executive function
self-regulation & control of behaviour
Parietal lobe
Process touch and helps pay attention to and locate objects, navigate our surroundings
primary somatosensory cortex
a ”map” of the body’s skin surface
Occipital lobe
Vision & contains the primary visual cortex which is necessary for sight
Temporal Lobe
Allows you to hear and understand language and to recognize objects and people
primary auditory cortex
processes auditory information
primary olfactory cortex
learning & memory of odors
Insular lobe
Allows us to perceive our inner world & perceives state of internal organs
primary taste cortex
responsible for the perception of taste & flavour
association cortex
integrates incoming information from sensory areas with existing knowledge to produce meaningful experience of the world
interhemispheric transfer
Helps the two hemispheres “talk” to each other
Broca’s area
Left frontal lobe
Damage → telegraphic speech
ex) “I hungry”
Can understand speech
Wernicke’s area
Temporal lobe
interpret sound & recognize language
phrenology
19th century belief that all mental faculties and characteristics are localized in specific brain regions and can be inferred from pattern of indentations on the skull
lesion
abnormal tissue resulting from disease, trauma, or surgical intervention
single dissociation
lesion to brain structure A disrupts function X but not function Y
double dissociation
lesion to brain structure A disrupts function X but not function Y, and lesion to brain structure B disrupts function Y but not function X
Deep brain stimulation
Stimulating specific parts of the brain with implanted electrodes
Transcranial Magnetic Stimulation (TMS)
Exposure to magnetic field to create temporary disruption or enhancement of cortical brain function
Transcranial Direct Current Stimulation (TDCS)
Low levels of direct current delivered via electrodes on the head to stimulate brain function
Functional Magnetic Resonance Imaging (FMRI)
Used to measure brain activity by detecting changes in blood oxygenation
PET
reveal changes in neurochemical activities (i.e., which neurotransmitters may be actively involved in a process)
single-cell recording
measurement of the electrical activity of a single neuron
Electroencephalography (EEG)
Recording of electrical waves from many thousands of neurons in the brain, gathered using electrodes placed on the scalp
Magnetoencephalography
The recording of the magnetic fields produced by the brain’s electrical currents
neural plasticity
brain’s ability to change and adapt throughout individual’s life
neurogenesis
process by which new neurons are formed in the brain
critical periods
specific timeframe during development when brain is particularly receptive to environmental stimuli, allowing for larger changes in neural connections
damage plasticity
neural modification/reorganization following injury
phantom limb syndrome
continuing sensation in limb that has been amputated