Ketone bodies

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Last updated 1:51 AM on 4/6/26
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8 Terms

1
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Some acetyl-coa is converted to ketone bodies like

Acetone, acetoacetate, beta hydroxybutyrate

2
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When are ketone bodies made and used

When starving and no carbs available for glycolysis and TCA.

3
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<p>Acetyl-coa and thiolase →</p>

Acetyl-coa and thiolase →

Acetoacetyl-CoA

4
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<p>HMG-CoA synthase</p>

HMG-CoA synthase

3-Hydroxy-3-methylglutaryl-CoA (HMG COA)

5
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6
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<p>HMG-CoA lyase</p>

HMG-CoA lyase

Acetoacetate + acetyl-coa

7
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<p>Beta-hydroxybutyrate dehydrogenase </p>

Beta-hydroxybutyrate dehydrogenase

Reduces acetoacetate to acetone and beta hydroxybutyrate

8
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What enzymes reconvert ketone bodies to acetyl-coa

Beta-ketoacyl-coa transferase and thiolase

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