G-Protein Coupled Receptors (GPCRs)

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Last updated 11:06 AM on 1/9/26
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6 Terms

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Why are GPCRs important?

They mediate smell

2
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How many GPCR isoforms exist?

Over 800 in humans

3
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What is the structure of GPCRs?

Seven transmembrane alpha helices

4
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How do GPCRs activate G proteins?

Ligand binding induces conformational change

5
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What makes G proteins molecular switches?

GTP binding activates them

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How is the signal amplified?

One GPCR activates multiple G proteins