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after the exposure to a protein antigen, antibodies will be immediately detectable in an individuals serum
T/F
false
name the T helper cell subset involved in antibody production
1) TH 1
2)TH 2
3) TH 17
4) CTL
2) TH2
B cells mature in which location?
1) bone marrow
2) bulbourethral gland
3) thymus
4) thyroid
1) Bone marrow
a molecule that is too small to be antigen is known as a(n) ——-. These molecules are typically associated with ——.
1) adjuvant; allergies
2) adjuvant; viruses
3) hapten; allergies
4) hapten; viruses
3) hapten; allergies
After antigen presentation and activation, antibodies are produced and secreted by which cells?
1) CD4 T cells
2) memory T cells
3) naïve B cells
4) plasma cells
4) plasma cells
Which antibodies are present in an individual with Type O blood?
1) anti-B antibodies
2) none
3) anti-A antibodies
4) anti-A and anti-B antibodies
4) anti-A and anti-B antibodies
which physical defense mechanism removes pathogens from potential sites of infection?
1)endothelial cells
2) resident bacteria of the GI tract
3)peristalsis
4) mucous membranes
??????? not 4…look it up
Identify the complement activation pathway that is triggered by the binding of an acute-phase protein to a pathogen
1) classical
2) alternate
3) lectin
4) cathelicidin
3) lectin
Helper T cells are activated by which of the following
1)MHC class I
2) MHC class II
3) either MHC class I or class II
4) both MHC class I or class II presenting the same antigen
2) MHC class II
IgM can cross the blood-placental barrier and it is important for natural passive immunity
T/F
False
Type one diabetes mellitus is an example of a ______ hypersensitivity reaction.
1) Type I
2) Type II
3) Type III
4) Type IV
4) Type IV
Which of the following leukocytes initiates inflammation?
2) eosinophil
2) mast cell
3) monocyte
4) neutrophil
2) mast cell
A patient is bitten by a dog with confirmed rabies infection. After treating the bite wound, the physician injects the patient with antibodies that are specific for the rabies virus to prevent the development of an inactive infection. This is an example of:
1) natural active immunity
2) artificial active immunity
3) natural passive immunity
4) artificial passive immunity
4) artificial passive immunity
Transferrin is an acute phase protein that works by sequestering iron
T/F
True
Where are acute phase proteins produced?
1) bone marrow
2) liver
3) pancreas
4) spleen
2) liver
Which chemical mediator is produced by lactobacilli in the female reproductive system and limits the growth of candida?
1)glucagon
2) glycogen
3) lactate
4) lactoferrin
3) lactate
Defensins target which process or structure of a microbial cell?
1) cell membrane
2) cell wall
3) DNA synthesis
4) protein synthesis
1) cell membrane
Which of the following describes the differentiation of stem cells into various blood cells
1) autopoiesis
2) biopoiesis
3) galactopoiesis
4) hematopoiesis
4) hematopoiesis
Toll-like receptors are example of which of the following?
1) NAMs
2) NKCs
3) PAMPs
4) PRRs
4) PRRs
Antibodies are made up of which of the following?
1) carbohydrates
2) glycoproteins
3) lipids
4) nucleic acids
2) glycoproteins
which molecular fragment on an antigen molecule do antibodies recognize and respond to?
1) epitope
2) Fab region
3) Fc region
4) variable region
1) epitope
which class of antibody provides protection against parasitic pathogens?
1) IgA
2) IgE
3) IgG
4) IgM
2) IgE
On an antibody, where do phagocytic cells bind during antibody- mediated opsonization?
1) disulfide bond
2) Fab region
3) Fc region
4) variable region
3) Fc region
Which MHC class is most likely found on macrophages?
1) class I
2) class II
3) both class I and class II
4) neither class I no class II
NOT # 3??????
The secondary immune response to the same antigen will result in less antibody production
T/F
False
Match each subgroup to its distinguishing feature
(look at pic)
3. helper T cell
1. CD4+ T cell
4. plasma cell
2. CD8+ T cell
match the example to the type of immunity being acquired
Match the class of vaccine to its proper description
Which type of hypersensitivity reaction involves IgG and IgM directed against cellular antigens?
1) Type I
2) Type II
3) Type III
4) Type IV
2) Type II
In a type I hypersensitivity, antibody/antigen interaction leads to:
1) basophil breakdown
2) mast cell degranulation
3) cytolysis of neutrophils
4) monocyte degranulation
2) mast cell degranulation
Type I hypersensitivity reactions can be either localized or systemic
True
Hemolytic transfusion reactions are an example of a type II hypersensitivity reaction
T/F
true
an immune complex is an aggregate of which of the following"?
1) antibody molecules
2) antigen molecules
3) antibody and antigen molecules
4) histamine molecules
3) antibody and antigen molecules
Type III hypersensitivity reactions involve cell bound antigens
T/F
False
Which of the following is NOT an effect of complement activation ? 1)opsonization
2) bacterial cell lysis
3) interference with viral replication
4)increased phagocytic activity
3) interference with viral replication
The antibodies that can bind to large parasites are
1) IgM
2) IgE
3) IgG
4) IgD
5) IgAthe best definition of an
2) IgE
The best definition antibody is
1) an immunoglobin
2) a serum protein
3) a protein made in response to an antigen that can combine with that antigen
4) a protein that inactivates or kills an antigen
NOT #2
thymic selection
1) destroys MHC molecules
2) destroys B cells that don't make antibodies against cell
3)activates B cells
4) destroys T cells that don't recognize self molecules of MHC
4) destroys T cells that don't recognize self molecules of MHC
the chemical mediators of anaphylaxis are
1) antigens
2) antibodies
3) found in basophils and mast cells
4) antigen-antibody complexes
3) found in basophils and mast cells
Which antibodies will bein the serum of a person with blood type B, Rh-?
1) Anti-B
2) anti-A, anti-B, anti-Rh
3) Anti-A
4) Anti-A, anti Rh
3) Anti-A