NPN - CREATININE/AMMONIA

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5 Terms

1
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creatinine

  • chief product of muscle metabolism

  • not affected by protein diet

  • end product of creatine metabolism (found in muscle storage of energy as creatine phosphate)

2
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0.6-1.3 mg/dL

  • normal value for men

3
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0.5-1.0 mg/dL

  • normal value for women

4
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ammonia

  • by product of amino acid deamination

  • removed from the circulation and converted to urea in the liver

  • the major source of circulating ammonia is the GI tract

  • it crosses the blood-brain barrier more readily than the ammonium ion

  • it is excreted as ammonium ion by the kidney and acts to buffer urine

5
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reye’s syndrome

  • acute metabolic disorder of the liver

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