NPN - CREATININE/AMMONIA
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5 Terms
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creatinine
chief product of muscle metabolism
not affected by protein diet
end product of creatine metabolism (found in muscle storage of energy as creatine phosphate)
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0.6-1.3 mg/dL
normal value for men
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0.5-1.0 mg/dL
normal value for women
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ammonia
by product of amino acid deamination
removed from the circulation and converted to urea in the liver
the major source of circulating ammonia is the GI tract
it crosses the blood-brain barrier more readily than the ammonium ion
it is excreted as ammonium ion by the kidney and acts to buffer urine
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reye’s syndrome
acute metabolic disorder of the liver
Note 
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