a nerve cell; the basic building block of the nervous system
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dendrite
the bush, branching extensions of a neuron that receive messages and conduct impulses toward the cell body
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glial cells
cells in the nervous system that support, nourish, and protect neurons` - provide structural support - supply nourishment to neurons - insulation to axons and other cells - Help remove neurons’ waste products - Play role in development of nervous system in human embryo - May also send and receive signals
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Glia disorders
- Dysfunction in glia cells may contribute to cognitiv impairment seen in schizo. Disorders + some forms of depressive disorders - Degeneration of glial tissue may lead to alzheimers - Key factor in chronic pain
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axon
the extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons or to muscles or glands
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myelin sheath
a layer of fatty tissue segmentally encasing the fibers of many neurons; enables vastly grater transmission speed of neural impulses as the impulse hops from one node to the next
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action potential
a neural impulse; a brief electrical charge that travels down an axon
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cell body (soma)
contains nucleus, DNA, RNA, info that makes that cell what it is
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terminal branches of axon
form junctions with other cells
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threshold
the level of stimulation required to trigger a neural impulse
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synapse
the junction between the axon tip of the sending neuron and he dendrite or cell body of the receiving neuron
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reuptake
a neurotransmitter's re-absorption by the sending neuron
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endorphins
natural, opiate-like neurotransmitters linked to pain control and to pleasure - Agonist: opiate dugs (morphine + heroin) - runner's high
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acetylcholine (ACh)
neurotransmitter that enables inv. muscle action, learning, arousal, and memory - excitatory - Agonst: nicotine - can produce excitatory + inhibitory
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ACh producing neurons
Alzheimer's disease - associated with a deterioration of . . . ?
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Dopamine (DA)
neurotransmitter that influences voluntary movement - Low levels = Parkinson's Disease - High Levels = Schizophrenia
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dopamine receptor
schizophrenia is associated with an excess of this neurotransmitter's receptors
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dopamine
under-supply associated brain produced tremors and decreased mobility associated with Parkinson's disease
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serotonin
neurotransmitter that affects mood, hunger, sleep, and arousal - Abnormal levels may contribute to OCD + depression - Agonist: LSD - reuptake after serotonin is in synapse
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serotonin
under-supply associated with depression, Prozac raises level
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Norepinephrine
neurotransmitter that helps control alertness and arousal
molecule similar enough to a neurotransmitter to bind to its receptor and mimic its effects
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antagonist
molecule similar enough to a neurotransmitter to bind to its receptor and block the neurotransmitter's functioning
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nervous system
the body's speedy, electrochemical communication network, consisting of all the nerve cells of the peripheral and central nervous systems
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central nervous system
the brain and spinal cord
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peripheral nervous system
the sensory and motor neurons that connect the central nervous system to the rest of the body. Made up of nerves that lie outside brain + spinal cord
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nerves
bundled axons that form neural "cables" connecting the central nervous system with muscles, glands, and sense organs
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somatic nervous system
made up of nerves that controls the voluntary movements of skeletal muscles - carry commands from CNS to muscles
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autonomic nervous system
part of the peripheral nervous system that controls the glands and the muscles of the internal organs: heart, blood vessles, smooth muscles, glands - controlled by CNS - Controls automatic, involuntary, visceral functions - Two branches: sympathetic + parasympathtic - fight or flight
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parasympathetic nervous system
the division of the autonomic nervous system that calms the body, conserving its energy
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endocrine system
the body's "slow" chemical communication system; a set of glands that secrete hormones into the bloodstream
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hormones
chemical messengers that are manufactured by the endocrine, travel through the bloodstream, and affect other tissues
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adrenal glands
a part of endocrine glands that sit just above the kidneys and secrete hormones (epinephrine and norepinephrine) that help arouse the body in times of stress
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pituitary glands
the endocrine system's most influential gland. Under the influence of the hypothalamus, the pituitary regulates growth and controls other endocrine glands
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lesion
tissue destruction; in the brain, a naturally or experimental caused destruction of brain tissue
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EEG
an amplified recording of the waves of electrical activity that sweep across the brain's surface. These waves are measured by electrodes placed on the scalp
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CT scan
a series of x-ray photographs taken from different angles and combined by computer into a composite representation of 3d brain. Portrays only structure Benefits: - reasonable - sees structure and what's phsycially wrong w/ brain
disadvantages - exposed to a lot fo x rays - drink contrast for scan --> some people can't tolerate that
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PET scan
a visual display of brain activity that detects where a radioactive form of glucose goes while the brain performs a given task
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MRI
a technique that uses magnetic fields and radio waves to produce computer generated images of soft tissues. Scans show brain structure
benefits: - more in-depth + clearer than ct
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fMRI
measures mvmt of blood molecules (index of neural acivity). Shows structure + function
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brainstem
the oldest part and central core of the brain, beginning where the spinal cord swells as it enters the skull. Responsible for automatic survival functions
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reticular formation
a nerve network in the brainstem that plays an important role in controlling arousal
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thalamus
relay station for sensory info - All of sensory info except smell → goes from sense organ → through thalamus
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cerebellum
the "little brain" at the rear of the brainstem; functions include processing sensory input and coordinating movement output and balance
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limbic system
the overall system of the brain that regulates emotions and controls behavior. Includes the Hippocampus, amygdala, hypothalamus, and other structures. Donut-shaped neural system located below the cerebral hemisphere; associated with emotions and drives
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amygdala
two lima bean-sized neural clusters in the limbic system; linked to emotion --> specifically fear and anger but others as well
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hypothalamus
a neural structure lying below the thalamus; it directs several body maintenance activities (eating, drinking, body temperature), helps govern the endocrine system via the pituitary gland, and is linked to emotion and reward (4 Fs)
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cerebral cortex
the intricate fabric of interconnected neural cells covering the cerebral hemispheres; the body's ultimate control and information processing center
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frontal lobes
portion of the cerebral cortex lying just behind the forehead; involved in speaking and muscle movements and in making plans and judgments - Prefrontal Cortex + Motor Cortex + Broca's Area
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parietal lobes
portion of the cerebral cortex lying at the top of the head and toward the rear; responsible for spacial orientation + touch
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occipital lobes
portion of the cerebral cortex lying at the back of the head; responsible for visual perception, including colour, form and motion.
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temporal lobes
portion of the cerebral cortex lying roughly above the ears; auditory processing + hearing Primary Auditory Cortex + Wernicke's Area
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motor cortex
mvmt of muscles frontal lobe
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sensory cortex
an area at the front of the parietal lobes that registers and processes body touch and movement sensations
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Wernicke's area
controls language comprehension Temporal lobe
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Broca's area
left frontal lobe production of speech
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visual cortex
interpreting incoming visual information
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brain plasticity
the brain's ability to change, especially during childhood, by reorganizing after damage or by building new pathways based on experience --> neural reorgininzation
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neurogenesis
the formation of new neurons
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corpus callosum
large bind of neural fibers connecting the two brain hemispheres and carrying messages between them
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split brain
a condition resulting from surgery that isolates the brain's two hemispheres by cutting the fibers (mainly those of the corpus callosum) connecting them
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chromosomes
threadlike strands of DNA (deoxyribonucleic acid) molecules that carry genetic information
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DNA
a complex molecular containing the genetic information that makes up the chromosomes
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genes
the biochemical units of heredity that make up the chromosomes and serve as the key functional units in hereditary transmission; segments of DNA capable of synthesizing a protein
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Terminal Buttons
small knobs that secrete neurotransmitters
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Synaptic vesicles
store various neurotransmitters
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absolute refractory period
min length of time after an action potential, during which another action potential/ impulse can not occur. After firing Action potential --> channels close up + time is needed before they are ready to open up again
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all or none law
a neuron either fires or it doesnt
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Presynaptic neuron
neuron that sends a signal across the gap
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postsynaptic neuron
neuron that recieves a signal
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postsynaptic potential
Graded (vary in size) and inc/dec the prob of a neural impulse being fired in the receiving cell in prop. to amnt of voltage change. Do not follow all-or-none law
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Inhibitory PSP
- stop action potentials - negative voltage shift - Dec likelihood that postsynaptic neuron will fire AP
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Excitatory PSP
- if it locks on → going to excite future cells + lots of more action potentials will happen → keep sending messages - positive voltage shift - Inc likelihood that postsynaptic neuron will fire AP
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synaptic pruning
brain eliminates extra synapses. cause neural restructuring that very likely has important consequences for normal and abnormal brain function
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Norepinephrine (NE)
- excitatory - Contributes to mood + arousal - Cocaine elevates activity in NE synapse - People who suffer from depression appear to have lower levels of NE - Can produce excitatory or inhibitory effects at virtually all synapses
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Sympathetic Division
mobilizes body’s resources for emergencies - creates fight or flight - release of hormones that ready body for exertion
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parasympathetic Division
conserves bodily resources - Activates processes that allow body to save + store energy
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Fight or flight
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afferent nerves
axons that carry fiber info outward from body to CNS
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efferent nerves
axons that carry info outward from CNS to periphery of body
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spinal cord
- Connects brain to rest of body through PNS - Houses bundles of axons that carry brain’s commands to - Most forms of paralysis result from spinal cord damage - Transmit signals from brain to neurons that signal body’s muscles to move
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cerebrospinal fluid
nourishes the brain + provides protective cushion for it - To enter: substances in blood have to cross blood-brain barrier - semipermeable membrane taht stops some chemicals from leaving bloodstream to enter brain
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electrical stimulation of the brain (ESB)
sending weak electrical current into brain to stimulate/activate it
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James Olds' research on pleasure centers
- investigating whether rats might be made uncomfortable by electrical stimulation of certain areas of their brain - electrical current given when rats enter certain part of cage to deter them - rats kept coming back + wanted to get shocked
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hindbrain
cerebellum, medulla, pons
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midbrain
reticular formation
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forebrain
cerebrum, cerebral cortex
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medulla
responsible for automatic functions
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pons
responsible for controlling sleep, dreams, sleep cycle, wakefulness
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cerebellum
responsible for balance, fine motor coordination
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Cerebrum
largest part of the brain. It is divided into two hemispheres, or halves, called the cerebral hemispheres. Areas within the cerebrum control muscle functions and also control speech, thought, emotions, reading, writing, and learning
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cerebral cortex
outermost layer of the brain that is associated with our highest mental capabilities
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somatosensory cortex
controls sensory info → only touch
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auditory cortex
Involves hearing, speaking, understanding written + verbal words
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Prefrontal Cortex
Reasoning, planning, paying attention, getting organises, decision making, impulse control
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homunculus brain map
- organized map of the proportional representation of the contralateral somatosensory or motor neurons on the cortex or passing though a part of the brain - as information comes to the brain from different parts of the body, information from the hand will all synapse in this region of the cortex
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mirror neurons
use to incorporate info about body language, social cues, etc.
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left hemisphere
- controls the right half of the body - Language - written and spoken - Simple math - Logical + analytical