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cerebellum function
receives information
feedforward control of muscles contractions
augment performance
motor control (no direct connection to LMN)
motor learning
cognition and social interaction
folia
ridges of the cerebellum
folliculi connected to the midline structure are called
nodulus
tonsils
chiari malformation
can herniate out
cerebellar peduncles
white matter pathway connecting the cerebellum to the brainstem
how info enters/exits brainstem
vermis
midline of cerebellum
what are the 3 lobes of the cerebellar cortex?
anterior, posterior, flocculonodular
what are the 3 zones to the cerebellum?
vermal, immediate, lateral
vermal zone
mostly flocculonodular lobe
eye movements
axial muscles for balance and posture
intermediate zone
vermis, anterior, posterior lobe
neck, trunk, and limb control
adjustments during movements
lateral zone
mostly posterior zone (some anterior)
modulation of fine control and movement
force, direction, speed, amplitude
motor learning
cognition
superior cerebellar peduncle
mostly efferent
middle cerebellar peduncle
only afferent
inferior cerebellar peduncle
efferent and afferent
the PICA supplies
inferior posterior cerebellum
lateral medulla
inferior cerebellar peduncle
the AICA supplies
anterior and inferior portion of cerebellum
the SCA supplies
superior cerebellum (upper half)
arbor vitae
white matter of the cerebellum branching
what are the cerebellar cortex layers?
molecular, purkinje, granule
granule layer
granular cells: only excitatory cells in cerebellum
golgi cells: inhibitory feedback
purkinje cell layer
cell bodies of purkinje cells
only output cells of cerebellum
inhibitory GABA
molecular layer
parallel fibers from granule cells
stellate cells
basket cells
what are the 4 deep nuclei of the cerebellum?
fastigal
interposed
globose and emboliform
dentate
only OUTPUTs from the cerebellum
all input into the cerebellum is
EXCITATORY
via peduncles
mainly GLUTAMATE as NT
act on deep nuclei
all output from the cerebellum is
INHIBITORY
only through the purkinje cells
GABA as the NT
spinocerebellar tract
sensory feedback to inform motor control
unconscious proprioception
enters through the cerebellum, NOT THE THALAMUS
does the cerebellum have direct connections to the skeletal muscles?
nope
but exerts significant influence over motor output
vestibulo-cerebellar circuits
cerebellum is receiving info about the vestibular system and has influence over postural control
only input that bypasses deep cerebellar nuclei
spinal-cerebellar circuit
cerebellum is receiving information in real-time on motor actions and able to update those motor actions
cortical input into the cerebellum
cerebellum is receiving info on proprioception and motor command to provide updates motor plans
cerebellar motor dysfunction is
IPSILATERAL
motor information has a DOUBLE CROSS
cerebellar motor signs
ataxia
dysmetria
dysarthria
nystagmus
incoordination of the muscles of the eyes
dysdiadochokinesia
hypotonia
intention tremor/cerebellar tremor
ataxia
impaired coordination of voluntary movement
inaccuracy with speed, force, or distance of movements
dysmetria
overshooting targets
finger to nose exam
dysarthria
inability to articulate words clearly
slurred speech
nystagmus
rhythmic involuntary movements of eyes
can't maintain fixation on target
drift from target and then jump back with a corrective saccade
dysdiadochokinesia
inability to perform fast alternating movements
coordination of agonist/antagonist muscles
intention tremor/cerebellar tremor
low frequency with voluntary movements
worsens as limb approaches end point
NOT PRESENT AT REST
damage to flocculonodular lobe/vestibulocerebellum/vermal
gait ataxia
titubation
nystagmus
gait ataxia
wide unsteady gait (staggering)
truncal ataxia (unable to walk toe to heel)
titubation
tremor of the head or axial body