Lymphoid

Primary lymph organs

bone marrow and thymus, also sites of lymphatic matriculation

bone marrow

sites of hematopoesis and maturation of b lympocytes

thymus

site of T lymphocytes maturation and positive negative strand selection

secondary lymph organs

Lymph nodes and spleen sight of immune response, diffuse lymph tissue and nodules

Lymph nodes

Filter lymph monitor for pathogen site of antigen representation and immune activation

Spleen

Filters blood reacts to blood home, pathogens removes old red blood cells and recycles iron

Diffuse lymph tissue and nodules

MALT tonsils, Piers patches sites of initial immune response in mucosal tissues

Lymphatic capillaries structure

Bind ended then wall tubes endothelium with no basal laminal, making them highly permeable

Lymphatic capillaries location

Found near blood, capillaries and skin and mucus membranes absent in the central nervous system, eyeballs,and inner ear

lymphatic capillaries primary valves

Overlapping and the cells act as one way flaps

Larger lymph vessel structure

Tinica media, SM, secondary valves

Larger lymph vessels lymphangion

Functional unit lymph vessel located between two secondary valves

Larger, lymph vessels, main trunks

Thoracic ducks (drains most of the body and right lymphatic ducts)

Mechanism of lymph movement

Propelled primarily by the connection of surrounding skeletal muscles, the muscular pump

Roll a valve in the mechanism of lymph movement

Prevents backflow

Larger vessels, and it’s involvement in the mechanism of lymph movement

Have smooth muscle in their walls that contracts rhythmically, lymphangion pump

Node types

Primary and secondary

Primary node type

Dense mostly small lymphocytes

Secondary note type

Lightly staining Geminal centers, size of b restoration, and staining mantle zone

List the pathway of lymphatics

Afferent lymphs to subcapsular sinus to trabecular sinus to cortex to medulla sinuses to effort, lymphatic vessels at the hilum and ascites from the blood can enter directly into the node via the higher endothelial venules

Spleen function

Filters, blood mounts, immune responses, and removes old red blood cells

Spleen capsule

DCT with myofibril blast and trabiculae

Spleen, structure of the white pulp

Lymphoid tissue around central arteries forms, peripheral lymphatic shafts

Spleen, structure, red pulp

Compound of spleen cords (reticular tissue) and spleen, sinuses- site of red blood cell breakdown

Spleen, structure of circulation

Blood enters, closed directly into sinuses or into cords, then into sinuses

Thymus function

Site of T cell, maturation and selection

Thymus structure capsule

Thin with trabiculae, dividing into lobules

Thymus, structure of cortex and medulla

No, typical reticular fibrous framework is made up of epithelialoreticular cells

Thymus structurethymus corpsule

Concentric layers of epithelialoreticular cells and medulla function, not entirely clear

Thymus structure lymphatic

efferent vessels only

Positive selection

Test is done T cells can interact with MHC molecule and the outcome T cells that can interact receive survival signals and proceed. These cells cannot die by a proptosis.

Negative selection

Test for self reactivity T cells that react to strong lead to self antigens are deleted and prevents autoimmunity. Only T cells can regulate MHC and aren’t self reactive and are allowed to mature and leave the thymus