Overview of Brain Structures and Neuron Function

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134 Terms

1

Cerebrum

The largest part of the brain, responsible for thinking, problem-solving, memory, and voluntary movements.

<p>The largest part of the brain, responsible for thinking, problem-solving, memory, and voluntary movements.</p>
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Cerebellum

The brain structure that controls balance, coordination, and fine motor movements.

<p>The brain structure that controls balance, coordination, and fine motor movements.</p>
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Ventricles

Fluid-filled spaces in the brain that produce and circulate cerebrospinal fluid (CSF) to protect and nourish the brain.

<p>Fluid-filled spaces in the brain that produce and circulate cerebrospinal fluid (CSF) to protect and nourish the brain.</p>
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4

Gray Matter

Contains neuron cell bodies; processes information and controls decision-making.

<p>Contains neuron cell bodies; processes information and controls decision-making.</p>
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White Matter

Contains myelinated axons; transmits signals quickly between different brain regions.

<p>Contains myelinated axons; transmits signals quickly between different brain regions.</p>
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Nerve Fibers

Axons that transmit electrical signals across the nervous system.

<p>Axons that transmit electrical signals across the nervous system.</p>
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7

Neuron

The basic cell of the nervous system that sends and receives electrical and chemical messages.

<p>The basic cell of the nervous system that sends and receives electrical and chemical messages.</p>
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Axon

A long fiber that transmits signals away from the neuron's cell body.

<p>A long fiber that transmits signals away from the neuron's cell body.</p>
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Dendrites

Short branches that receive signals from other neurons.

<p>Short branches that receive signals from other neurons.</p>
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Synapse

The tiny gap between neurons where neurotransmitters are released to pass signals.

<p>The tiny gap between neurons where neurotransmitters are released to pass signals.</p>
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Soma (Cell Body/Perikaryon)

The main part of a neuron that contains the nucleus and controls cell functions.

<p>The main part of a neuron that contains the nucleus and controls cell functions.</p>
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Nucleus

Stores genetic material and controls neuron activity.

<p>Stores genetic material and controls neuron activity.</p>
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Ribosomes & Rough ER

Produce proteins necessary for neuron function.

<p>Produce proteins necessary for neuron function.</p>
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14

Mitochondria

Provides energy for the neuron.

<p>Provides energy for the neuron.</p>
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15

Connectional Specificity

Neurons form precise connections with specific other neurons rather than random ones.

<p>Neurons form precise connections with specific other neurons rather than random ones.</p>
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Dynamic Polarization

Electrical signals flow in one direction within a neuron, from dendrites to the axon.

<p>Electrical signals flow in one direction within a neuron, from dendrites to the axon.</p>
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Axonal Transport

The process of moving materials inside a neuron.

<p>The process of moving materials inside a neuron.</p>
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Anterograde Transport

Moves materials from the cell body to the axon terminal (forward, using kinesin).

<p>Moves materials from the cell body to the axon terminal (forward, using kinesin).</p>
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Retrograde Transport

Moves materials from the axon terminal back to the soma (backward, using dynein).

<p>Moves materials from the axon terminal back to the soma (backward, using dynein).</p>
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Kinesin

A motor protein that carries materials along microtubules in the anterograde direction.

<p>A motor protein that carries materials along microtubules in the anterograde direction.</p>
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Dynein

A motor protein that carries materials in the retrograde direction.

<p>A motor protein that carries materials in the retrograde direction.</p>
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22

Unipolar Neuron

One extension from the soma.

<p>One extension from the soma.</p>
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Pseudounipolar Neuron

One extension that splits into two.

<p>One extension that splits into two.</p>
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Bipolar Neuron

Two processes (one dendrite, one axon).

<p>Two processes (one dendrite, one axon).</p>
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Multipolar Neuron

Multiple dendrites, one axon (most common).

<p>Multiple dendrites, one axon (most common).</p>
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26

Astrocytes

Star-shaped cells that provide nutrients, clean waste, and maintain the blood-brain barrier.

<p>Star-shaped cells that provide nutrients, clean waste, and maintain the blood-brain barrier.</p>
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27

Microglia

Act as the brain's immune cells, removing dead cells and fighting infections.

<p>Act as the brain's immune cells, removing dead cells and fighting infections.</p>
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28

Myelin

A fatty coating around axons that speeds up electrical signals.

<p>A fatty coating around axons that speeds up electrical signals.</p>
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Oligodendrocytes

Myelinate axons in the central nervous system (CNS) (brain and spinal cord).

<p>Myelinate axons in the central nervous system (CNS) (brain and spinal cord).</p>
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Schwann Cells

Myelinate axons in the peripheral nervous system (PNS) (nerves outside the brain and spinal cord).

<p>Myelinate axons in the peripheral nervous system (PNS) (nerves outside the brain and spinal cord).</p>
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Ependymal Cells

Produce cerebrospinal fluid (CSF) and help circulate it in the brain's ventricles.

<p>Produce cerebrospinal fluid (CSF) and help circulate it in the brain's ventricles.</p>
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32

Neural Signal

The way neurons send messages using electrical and chemical signals.

<p>The way neurons send messages using electrical and chemical signals.</p>
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33

Rate Code

The brain understands information based on how fast neurons fire signals.

<p>The brain understands information based on how fast neurons fire signals.</p>
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34

Population Code

Information is carried by groups of neurons working together.

<p>Information is carried by groups of neurons working together.</p>
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35

Temporal Code

The timing of neuron signals carries information.

<p>The timing of neuron signals carries information.</p>
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Resting Membrane Potential

The natural electrical charge inside a neuron when it's not sending signals. Usually around -70mV.

<p>The natural electrical charge inside a neuron when it's not sending signals. Usually around -70mV.</p>
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Ion

A tiny charged particle.

<p>A tiny charged particle.</p>
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Cation

A positively charged ion (e.g., Na⁺, K⁺).

<p>A positively charged ion (e.g., Na⁺, K⁺).</p>
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Anion

A negatively charged ion (e.g., Cl⁻).

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Lipid Bilayer

The double-layered, fatty covering of a cell that keeps the inside separate from the outside.

<p>The double-layered, fatty covering of a cell that keeps the inside separate from the outside.</p>
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Polypeptide

A chain of amino acids that make up proteins, which help cells function.

<p>A chain of amino acids that make up proteins, which help cells function.</p>
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Ion Channel

A tiny tunnel in the cell membrane that allows specific ions to move in or out.

<p>A tiny tunnel in the cell membrane that allows specific ions to move in or out.</p>
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Selective Permeability of a Membrane

The membrane only lets certain things pass through, like specific ions.

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Ion Pump

A special protein that pushes ions across the membrane, often using energy (ATP).

<p>A special protein that pushes ions across the membrane, often using energy (ATP).</p>
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45

Diffusion

When molecules naturally spread out from an area of high concentration to low concentration.

<p>When molecules naturally spread out from an area of high concentration to low concentration.</p>
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Concentration Gradient

The difference in the amount of a substance between two areas, which causes diffusion.

<p>The difference in the amount of a substance between two areas, which causes diffusion.</p>
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Electrical Current

The flow of electrical charge, like a river of electrons or ions moving through a conductor.

<p>The flow of electrical charge, like a river of electrons or ions moving through a conductor.</p>
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Electrical Potential (Voltage)

The force that pushes electrical charge, like the pressure in a water pipe.

<p>The force that pushes electrical charge, like the pressure in a water pipe.</p>
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Voltage

Another word for electrical potential, measured in volts (V) or millivolts (mV).

<p>Another word for electrical potential, measured in volts (V) or millivolts (mV).</p>
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Electrical Conductance

How easily electricity (or ions) can flow through something. High conductance = easy flow.

<p>How easily electricity (or ions) can flow through something. High conductance = easy flow.</p>
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Electrical Resistance

How much something blocks the flow of electricity. High resistance = hard for electricity to pass.

<p>How much something blocks the flow of electricity. High resistance = hard for electricity to pass.</p>
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Membrane Potential

The difference in electrical charge inside vs. outside a neuron. This is how neurons send signals.

<p>The difference in electrical charge inside vs. outside a neuron. This is how neurons send signals.</p>
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Microelectrode

A tiny needle-like tool that can measure the electrical charge inside a neuron.

<p>A tiny needle-like tool that can measure the electrical charge inside a neuron.</p>
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Ionic Equilibrium Potential

The point where an ion is balanced between inside and outside the cell, so it stops moving.

<p>The point where an ion is balanced between inside and outside the cell, so it stops moving.</p>
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Ionic Driving Force

The push or pull on an ion based on its equilibrium potential and membrane potential.

<p>The push or pull on an ion based on its equilibrium potential and membrane potential.</p>
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Nernst Equation

A formula that calculates an ion's equilibrium potential based on its concentration inside vs. outside the cell.

<p>A formula that calculates an ion's equilibrium potential based on its concentration inside vs. outside the cell.</p>
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Sodium-Potassium Pump

A special pump that moves sodium (Na⁺) out and potassium (K⁺) in, helping the neuron stay at rest.

<p>A special pump that moves sodium (Na⁺) out and potassium (K⁺) in, helping the neuron stay at rest.</p>
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Goldman Equation

A formula that calculates the membrane potential by considering multiple ions (not just one like Nernst does).

<p>A formula that calculates the membrane potential by considering multiple ions (not just one like Nernst does).</p>
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59

Depolarization

When the inside of a neuron becomes more positive, making it more likely to fire a signal.

<p>When the inside of a neuron becomes more positive, making it more likely to fire a signal.</p>
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Gating (of Ion Channels)

When ion channels open or close, controlling which ions can enter or leave the neuron.

<p>When ion channels open or close, controlling which ions can enter or leave the neuron.</p>
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Axon

The long, thin part of a neuron that sends electrical signals away from the cell body to communicate with other neurons.

<p>The long, thin part of a neuron that sends electrical signals away from the cell body to communicate with other neurons.</p>
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Voltage-Gated Sodium Channels

Special gates in the axon that open when the neuron needs to send a signal, letting sodium (Na⁺) rush in.

<p>Special gates in the axon that open when the neuron needs to send a signal, letting sodium (Na⁺) rush in.</p>
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Voltage-Gated Potassium Channels

Gates that open after sodium, letting potassium (K⁺) flow out to reset the neuron.

<p>Gates that open after sodium, letting potassium (K⁺) flow out to reset the neuron.</p>
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Threshold

The point where a neuron must reach to send a signal (~ -55mV). If it doesn't reach this, no signal happens.

<p>The point where a neuron must reach to send a signal (~ -55mV). If it doesn't reach this, no signal happens.</p>
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Rising Phase

Sodium (Na⁺) rushes into the axon, making it more positive inside.

<p>Sodium (Na⁺) rushes into the axon, making it more positive inside.</p>
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Overshoot

The inside of the neuron becomes more positive than the outside.

<p>The inside of the neuron becomes more positive than the outside.</p>
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Falling Phase

Potassium (K⁺) flows out of the neuron, making the inside negative again.

<p>Potassium (K⁺) flows out of the neuron, making the inside negative again.</p>
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Undershoot (Hyperpolarization/After-Hyperpolarization)

The neuron becomes even more negative than its resting state before returning to normal.

<p>The neuron becomes even more negative than its resting state before returning to normal.</p>
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Absolute Refractory Period

The neuron cannot fire another signal because sodium channels are completely inactive.

<p>The neuron cannot fire another signal because sodium channels are completely inactive.</p>
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Relative Refractory Period

The neuron can fire another signal, but only if it gets a very strong stimulus because it's still recovering.

<p>The neuron can fire another signal, but only if it gets a very strong stimulus because it's still recovering.</p>
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Channelopathy

A disease caused by defective ion channels, which can affect neuron signaling (e.g., epilepsy).

<p>A disease caused by defective ion channels, which can affect neuron signaling (e.g., epilepsy).</p>
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Tetrodotoxin (TTX)

A deadly toxin found in pufferfish that blocks sodium channels, preventing neurons from sending signals.

<p>A deadly toxin found in pufferfish that blocks sodium channels, preventing neurons from sending signals.</p>
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Myelination

A fatty covering (myelin) around the axon that makes signals travel much faster.

<p>A fatty covering (myelin) around the axon that makes signals travel much faster.</p>
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Axon Width

Thicker axons send signals faster because there is less resistance to ion flow.

<p>Thicker axons send signals faster because there is less resistance to ion flow.</p>
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Myelinated Axon

An axon covered with myelin, making signals travel quickly.

<p>An axon covered with myelin, making signals travel quickly.</p>
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Nodes of Ranvier

Gaps between myelin where ion channels are located, helping speed up signals.

<p>Gaps between myelin where ion channels are located, helping speed up signals.</p>
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Saltatory Conduction

How signals jump from one Node of Ranvier to another instead of moving slowly down the axon.

<p>How signals jump from one Node of Ranvier to another instead of moving slowly down the axon.</p>
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Spike-Initiation Zone

The part of a neuron (usually the axon hillock) where action potentials (signals) begin.

<p>The part of a neuron (usually the axon hillock) where action potentials (signals) begin.</p>
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Oscilloscope/Voltammeter

A tool that measures electrical signals inside neurons.

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Voltage Clamp

A technique that holds the voltage of a neuron steady to study ion channel activity.

<p>A technique that holds the voltage of a neuron steady to study ion channel activity.</p>
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Patch Clamp

A method used to study the activity of one single ion channel in a neuron.

<p>A method used to study the activity of one single ion channel in a neuron.</p>
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Synaptic Transmission

The process where one neuron sends a signal to another neuron or muscle using chemicals or electricity.

<p>The process where one neuron sends a signal to another neuron or muscle using chemicals or electricity.</p>
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Loewi Experiment

Otto Loewi discovered that nerves release chemicals to control the heart.

<p>Otto Loewi discovered that nerves release chemicals to control the heart.</p>
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Electrical Synapse

A direct, fast connection between neurons where signals pass through gap junctions (tiny tunnels between cells).

<p>A direct, fast connection between neurons where signals pass through gap junctions (tiny tunnels between cells).</p>
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Chemical Synapse

A slower but more flexible way of communication where a neuron releases neurotransmitters to send messages.

<p>A slower but more flexible way of communication where a neuron releases neurotransmitters to send messages.</p>
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Postsynaptic Potential

The change in electrical charge inside the receiving neuron after getting a signal.

<p>The change in electrical charge inside the receiving neuron after getting a signal.</p>
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Active Zone

The area in a neuron's axon terminal where neurotransmitters are released.

<p>The area in a neuron's axon terminal where neurotransmitters are released.</p>
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Neuromuscular Junction

The synapse between a motor neuron and a muscle, where signals tell muscles to contract.

<p>The synapse between a motor neuron and a muscle, where signals tell muscles to contract.</p>
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Glutamate

The main excitatory neurotransmitter, helping neurons send signals.

<p>The main excitatory neurotransmitter, helping neurons send signals.</p>
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GABA (Gamma-Aminobutyric Acid) & Glycine

The main inhibitory neurotransmitters, helping neurons slow down or stop firing.

<p>The main inhibitory neurotransmitters, helping neurons slow down or stop firing.</p>
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Acetylcholine (ACh)

A neurotransmitter that helps with muscle movement, learning, and memory.

<p>A neurotransmitter that helps with muscle movement, learning, and memory.</p>
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Transporters

Proteins that move neurotransmitters back into the neuron after they are used.

<p>Proteins that move neurotransmitters back into the neuron after they are used.</p>
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Voltage-Gated Calcium Channel

A special gate that opens when a neuron is ready to release neurotransmitters, allowing calcium (Ca²⁺) inside.

<p>A special gate that opens when a neuron is ready to release neurotransmitters, allowing calcium (Ca²⁺) inside.</p>
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Exocytosis

The process of releasing neurotransmitters from the neuron.

<p>The process of releasing neurotransmitters from the neuron.</p>
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Endocytosis

The process of recycling neurotransmitter vesicles after release.

<p>The process of recycling neurotransmitter vesicles after release.</p>
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Transmitter-Gated Ion Channels

Special channels that open when a neurotransmitter binds, letting ions in or out.

<p>Special channels that open when a neurotransmitter binds, letting ions in or out.</p>
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Excitatory Postsynaptic Potential (EPSP)

A signal that makes the next neuron more likely to fire (caused by positive ions entering).

<p>A signal that makes the next neuron more likely to fire (caused by positive ions entering).</p>
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Inhibitory Postsynaptic Potential (IPSP)

A signal that makes the next neuron less likely to fire (caused by negative ions entering).

<p>A signal that makes the next neuron less likely to fire (caused by negative ions entering).</p>
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G-Protein-Coupled Receptors (GPCRs)

A type of receptor that starts a slow but long-lasting signal inside the neuron.

<p>A type of receptor that starts a slow but long-lasting signal inside the neuron.</p>
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Second Messengers & Metabotropic Receptors

These help relay signals inside the cell when GPCRs are activated.

<p>These help relay signals inside the cell when GPCRs are activated.</p>
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