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Hypertension, Diabetes, Fluid Imbalances, Electrolyte Imbalances, Acid-Base Imbalances, Anemia
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Define Essential (Primary) Hypertension
Most common hypertension, no known cause.
Define Secondary Hypertension
Hypertension caused by disease states (kidney disease) or as an adverse effect of medications;
Treatment = removal of causative factor.
Risk Factors for Essential Hypertension (11)
Positive Genetic History
Excess sodium intake
Inactivity
BMI > 25
High alcohol consumption
African American ethnicity
Smoking
Hyperlipidemia
Diabetes
Stress
Age > 60 or postmenopausal
Expected BP Range
Systolic < 120
Diastolic < 80
Elevated BP Range
Systolic 120 – 129
Diastolic < 80
Stage 1 Hypertension BP Range
Systolic 130 – 139
Diastolic 80 -89
Stage 2 Hypertension Range
Systolic Equal to or > 140
Diastolic Equal to or > 90
Hypertensive Crisis BP Range
Systolic Greater than 180
Diastolic equal to or > 120
What Should Be Assessed Prior to Administrating Antihypertensives? (4)
BP & Pulse (withhold if low)
BUN & Creatinine
Electrolyte levels
Fluid Imbalances (edema, weight gain, I&O)
Hypertension Health Promotion (7)
Maintain a BMI < 25
Diabetic clients should keep blood glucose within recommended range
Limit caffeine & alcohol; Smoking cessation
Use stress management techniques during stress
Aerobic Exercise 3x/week
DASH, Heart Healthy Diet
Limit Sodium & Fat intake
Clinical Manifestations of Hypertension (6)
Few to no manifestations
Headaches
Facial flushing
Dizziness
Fainting
Retinal Changes
Visual Disturbances
What are the 2 Beta Blockers to know?
metoprolol
atenolol
Why are Beta Blockers Contraindicated in Asthma
Bronchoconstriction Risk
Beta Blockers Action
Blocks beta adrenergic receptors (SNS) for lower BP & HR
What Should be Assessed Prior to Beta Blocker Administration?
BP & HR
When is it unsafe to give Beta Blockers?
Low BP & HR - worsens symptoms
2nd or 3rd degree heart block
Severe asthma
What is the Thiazide Diuretic to know?
Hydrochlorothiazide
Labs That Should be Monitored with Diuretics
Electrolyte levels - potassium, sodium, calcium, magnesium
Renal function
Glucose & Uric acid - can increase with thiazides
Lab That IS Monitored with Diuretics
Potassium
Loop & Thiazide = hypokalemia
Potassium-Sparing = hyperkalemia
What can occur if potassium is low? S/S
Hypokalemia
Muscle weakness & cramps
Dysrhythmias (irregular pulse)
Fatigue
Constipation
What can occur if potassium is high? S/S
Hyperkalemia
Cardiac arrhythmias (peaked T wave)
Muscle weakness
Paresthesia
Diuretic Client Education
Monitor for S/S of hypokalemia & report
Keep all appointments to monitor treatment effectiveness & electrolyte levels
Take diuretics prior to 6 PM
Increase consumption of potassium (bananas)
Causes of Hypokalemia with Loop & Thiazide Diuretics
Inhibit water & sodium reabsorption & increase potassium excretion
Causes of Hyperkalemia with Potassium-Sparing Diuretics
Retain potassium
What are the 2 ACE inhibitors to know?
Lisinopril
Enalapril
Adverse Effects of ACE Inhibitors
Hypotension
Heart Failure Evidenced by Edema
Heart & Kidney Complications
Dry Cough - may indicate risk of angioedema
Angioedema
Priority Adverse Effect of ACE Inhibitors & Why
Dry Cough
Risk of angioedema
Define Angioedema
Swelling of tongue/glottis, can lead to life-threathening airway obstruction
What is a hypertensive crisis?
Severely elevated blood pressure
Occurs when client do not adhere to medications
Life-threatening
Manifestations of a Hypertensive crisis
Severe Headaches
Very High BP
Blurred vision
Dizziness & Disorientation
Epistaxis
Nursing actions during a hypertensive crisis (6)
Recognize manifestations
Administer IV Antihypertensives – nitroprusside, nicardipine, labetalol
Goal – Lower BP by 20-25% in first hour; do not drop less than 140/90
Medication Administration – monitor BP every 5-15 minutes
Assess Neuro Status – Pupils, LOC, Muscle strength; cerebrovascular changes
Monitor ECG to assess cardiac status
Define Type 1 Diabetes
Autoimmune destruction of beta cells that produce insulin cause insufficient insulin
Define Type 2 Diabetes
Progressive condition due to inability of body’s cells to respond to present insulin (insulin resistance)
Who Should be Screened for Diabetes? (9)
BMI > 25
1st degree relative with diabetes
45 years or older
Sedentary Lifestyle
History of vascular disease, PCOS, gestational diabetes, birth to an infant > 9 lbs
African American, Hispanic, Asian, American Indian, or Pacific Islander
BP consistently greater than 140/90
A1C > 5.7%, impaired fasting glucose, impaired glucose tolerance
HDL < 35; Triglycerides > 250
How are diabetic screenings completed?
A1C or fasting blood glucose
Prediabetic Reference Ranges
Glucose above expected range but below diabetic range
A1C - 5.7 - 6.4%
Diagnostic Criteria for Diabetes (4)
Manifestations of diabetes (3 Ps, kussmaul, infections) && random blood glucose > 200
Fasting blood glucose > 126
2 hr postprandial glucose > 200 with oral glucose tolerance test
A1C - > or equal to 6.5
Normal Fasting Blood Glucose Range
No food for > or equal to 8 hrs.
70 - 100
Normal Postprandial Blood Glucose Range
2 hrs after eating
< 140
Normal Random Blood Glucose Test
< 200
Normal A1C
< 5.7
Hypoglycemia Levels
< 70
Hyperglycemia Levels
> 140 fasting
> 200 random
Diabetic A1C Range
6.5 - 8%
A1C Goal for Diabetics
< 7 %
General Hypoglycemia S/S (9)
Mild shakiness
Confusion
Sweating
Palpitations
Headache
Lack of coordination
Blurred vision
Seizures & coma
Slow Glucose Decline Hypoglycemia S/S (4)
Headache
Confusion
Fatigue
Drowsiness
Rapid Glucose Decline Hypoglycemia S/S
Tachycardia
Diaphoresis
Nervousness
Interventions to Treat Hypoglycemia
Fast-acting carbs
Glucagon or IV dextrose
When are Carbohydrates Given in Hypoglycemia
If client is able to swallow & is responsive
Carbohydrate Hypoglycemia Intervention
Administer 15-20 g of readily absorbable carbs
Recheck BG after 15 mins
Retreat if manifestations continue or glucose is < 70
Fast Acting Carbs/Glucose
4-6 oz of fruit/soft drinks
Glucose tablets/gel
6-10 hard candies
1 tbsp of honey
When is Glucagon Given
Unconscious Clients
When are Glucagon & IV Dextrose Given
For clients unable to swallow
Glucagon Intervention Hypoglycemia
Place client in lateral position to prevent aspiration
Administer Glucagon SubQ or IM
Repeat in 10 mins if still unconscious
Once conscious consume oral carbs
Hyperglycemia S/S
3 Ps -Polydipsia, Polyuria, Polyphagia
Hot, dry skin
Fruity Breath
Regular Insulin (Short Acting) - Examples
Humalin R
Novolin R
Regular Insulin - Onset, Peak, & Duration
Onset - 30 mins - 1 hr
Peak 2-5 hrs
Duration - 5 - 8 hrs
When is Regular Insulin Administered
15-30 minutes before meals to control postprandial hyperglycemia
Long-Acting Insulin - Examples
Glargine
Detemir
Long-Acting Insulin - Onset, Peak, Duration
Onset - 1 - 4 hrs
Peak - None
Duration - Dose dependent
Small dose duration = 12 hrs
Large dose duration = 24 hrs
Long-Acting Insulin - Dose Dependent Duration Range
12 - 24 hrs.
What Insulins are Mixed
Regular & NPH
Steps for Mixing Insulin
Inspect Vials for contaminants
Roll NPH between palms
Clean vial tops with alcohol
Inject air into NPH & pull needle out
Inject air into Regular
Withdrawal regular insulin dose
Withdrawl NPH insulin dose
Confirm dose (2 confirmation)
What is the Biguanide Drug to know?
Metformin
What should clients monitor for when taking metformin? S/S
Lactic acidosis
Myalgia (muscle pain & cramps)
Sluggishness
Somnolence
Hyperventilation
What should clients take metformin with & why?
Take with food to decrease adverse GI effects
What should client’s avoid when taking metformin?
Avoid alcohol
Increases lactic acidosis risk
What are the 2 Sulfonylureas to know?
Glipizide
Glimepiride
What should the client avoid when taking sulfonylureas?
Alcohol
Disulfiram reaction
All Antidiabetics have a risk of what?
Risk for hypoglycemia
Define Dehydration
Lack of fluid in body from insufficient intake or excess loss.
Define Hypovolemia (fluid volume deficit)
Isotonic dehydration
Lack of water & electrolytes decreasing blood volume
Dehydration S/S (10)
Dizziness
Dry mouth & mucous membranes
Tongue – Dry, furrowed (grooves), shrunken
Decreased Urine Output & dark & concentrated urine
Dry Skin
Thirst
Headache
Vitals - Low BP, fever, tachycardia,
Hypothermia - as fever goes down
Chest pain
Body Temperature in Dehydration (2)
Fever - can result in skin loss (sweating) resulting in dehydration
Prolonged fever - body will try to maintain homeostasis by causing hypothermia & cold skin
Why are the elderly higher at risk of dehydration? (4)
Loss of skin elasticity
Kidney - decreased glomerular filtration & concentrating ability
Loss of muscle mass - Muscles hold onto more water
Diminshed thirst sensastion
What are the interventions for hypotension? (5)
Assess gait stability & encourage client to ask for assistance when ambulating (fall risk)
Encourage client to change positions slowly
Rehydrate & Administer IV fluids/blood transfusions if needed
Vasoconstrictors – increase BP & improve myocardial perfusion
Frequently monitor BP & HR & LOC
What is Urine Specific Gravity?
A measure of the kidney’s ability to concentrate or dilute urine
Measure hydration & renal function
What is Normal Range of Urine Specific Gravity
1.005 - 1.030
Urine Specific Gravity for Dehydration
> than 1.030
High Urine Specific Gravity - Urine Appearance
Urine will be more concentrated.
Dark yellow to amber, strong odor, possibly cloudy
Define Overhydration
Too much fluid in body from excess intake or ineffective removal.
Define Fluid Overload
Excess of water/fluid (hemodilution); Risk of pulmonary edema & CHF
Define Hypervolemia
Fluid volume excess (excess water & electrolytes)
S/S of Overhydration
Vitals – Tachycardia, bounding pulse, hypertension, tachypnea, increased central venous pressure
Tongue Appearance – swollen, enlarged & moist; impressions of teeth may be present
Neuro – Changes in mental status, confusion, seizures, increased ICP
Respiratory – SOB, dyspnea, crackles, increased RR, dry cough that can become productive with foamy, frothy, bloody sputum (flash pulmonary edema)
Others – Pitting edema of extremities, cool skin, ascites, nausea, weight gain
What Does the Tongue look like in Over hydration?
Swollen, enlarged & moist; impressions of teeth may be present
1+ Pitting Edema
< 2 mm depression barely detectable
Immediate rebound
2+ Pitting Edema
2-4 mm deep pit
Few seconds to rebound
3+ Pitting Edema
5-7 mm deep pit
10 to 12 seconds to rebound
4+ Pitting Edema
> 7 mm very deep pit
20 seconds to rebound
S/S of Fluid Overload (Vitals)
Hypertension, tachycardia, tachypnea, increased RR, decreased O2 sat
Interventions for Fluid Overload
D – diuretics
R- restrict fluids & sodium
A – assess daily weight
I – I & O
N – Na+ levels monitored & other electrolytes
How much Weight Gain is Stable in Heart Failure?
2 lbs a day = stable
How Much Weigh Gain is Bad?
> 2 lbs a day or 5 lbs in a week = fluid overload
1 kg (2.2 lbs) =
1 L of fluid
Excess weight gain may indicate?
Worsening heart failure or pulmonary edema
Sodium Range
136 - 145
Hyponatremia Levels
Below 136
S/S of Hyponatremia
Muscle cramps, confusion, weakness
Hypervolemic
What Type of IV solutions treat Hyponatremia?
Hypertonic (high salt)