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What hormones stimulate uterine growth?
High levels of estrogen & progesterone
When may a woman begin “showing”?
After the 14th week
Lightening
When the fetus begins descending into the pelvis
Nullipara - 2 wks b4 labor
Multipara - at the start of labor
Hegar Sign
Softening & compression of lower uterine segment that causes urinary frequency
How may Braxton Hicks contractions be ceased/alleviated?
With walking or excercise
Uterine Souffle
Bruit heard/blowing sound of maternal blood flow thru uterine arteries
Funic Souffle
Synchronous with FHR due to fetal blood running thru umbilical cord
Ballottement
Palpation of a floating fetus by bouncing it gently and feeling for a rebound

Quickening
1st feeling of fetal recogniton via fetal movements/flutters
The week quickening occurs gives a clue to
Gestation duration
Goodell Sign
Softening cervical tip from increased vascularity
Friability
how sensitive the tissue begins
Women may bleed after vaginal examination or deep penetration
Operculum
Mucus plug that fills the endocervical canal
***rich in immunoglobulin & acts as a barrier
Chadwick Sign
Violet/blue color of the vaginal mucosa and cervix from increased vascularity

Leukorrhea
White/gray vaginal discharge
Since pregnant women are more vulnerable to infections…
Vaginal pH drops to prevent ascending bacterial infections
What may be seen due to increased vaginal vascularity?
High sexual interest (2nd trimester)
Edema/varicosities of vulva
What may explain why BP remains the same or even drops slightly in pregnant woman?
Progesterone has vasodilatory effects = decreased SRV
Supine Hypotensions/Vena Cava Syndrome
When a woman lays on her back she has reflex brady → reduced CO
Cardiac Structural Adaptations
Cardiac hypertrophy
PMI shifted upward
Splitting of S1 & S2
S3 may be heard from rapid diastolic filling
Systolic ejection murmur in 96%
Physiologic Anemia of Pregnancy
Plasma increase > RBC production
⬇ hgb & hct levels
Hemodilution!!!
Respiratory Adaptations
Uterus has upward pressure on the diaphragm
Chest > abdominal breathing
Dyspnea
Voice change
Impaired hearing
Why are pregnant women in a state of respiratory alkalosis?
Constant hyperventilation with reduced CO2
Effect on gums from increased estrogen levels?
Swollen
Bleed easily
Epulis
Red, raised nodule on gums (may enlarge)

Ptyalism
Excess salivation
Amplified when nauseated, due to decreased in swallowing
Upper GI Effects
Increased progesterone
Decreases tone (heartburn)
Reduces peristalsis (constipation)
Pica
Nonfood cravings
Gallbladder Adaptations
Increased progesterone
Distended/hypercholest/gallstones
Cholestasis → itching/jaundice
Liver Adaptations
Hemodilution → ⬇ albumin//protein
ALK phos. levels increase
Although the kidneys enlarge during pregnancy
Urinary stasis → slow urine flow rate
⬆ UTI risk
Best position to preserve renal function during pregnancy?
Side-lying position increases
renal perfusion
urine output
⬇ edema
Some women may feel thirsty
Early in the pregnancy
Why may glucosuria be seen?
Impaired tubular reabsorption of glucose
What should we look out for in women on diuretics?
Hypovolemia
Reduced placental perfusion
Melasma
Hyperpigmentation

What has been shown to reduce stretch mark redness?
Pulsed laser therapy
Why may women experience palmar erythema?
From the high estrogen levels
MSK Adaptations
Lordosis
Waddling gait
Leg cramps
RLS
Headaches may indicate
Pre-eclampsia
Why is carpal tunnel seen in pregnant women>
The edema compresses peripheral nerves
Human Chorionic Gonadotropin (hCG)
Maintains production of estrogen/progesterone until placenta can take over
⬆ lvls: DS/multiple gest.
⬇ lvls: miscarriage/ectopic
> 25 = 🤰🏻
Estrogen interferes with _________ metabolism
Folic acid
Cortisol stimulates
production of insulin during pregnancy
Home preggo test should be done with
First voided morning speciment
Anticonvulsants/tranquilizers can cause
False (+) results
Diuretics/promethazine can cause
False (-) results