* Examines children whose early like was spent in horribly inadequate orphanages in Romania in the late 1980s and early 1990s
* Children had almost no contact with caregivers
* Shortly after the collapse of the communist rule in Romania, a number of these children were adopted by families in Great Britain
* To evaluate the long term effects of their early deprivation, the physical, intellectual, and social development of about 150 of the Romanian children were examined at age 6, and to compare examined a group of British born children who had been adopted into British homes before they were six months.
* The question was whether human nature is sufficiently flexible that the Romanian born children could overcome the extreme deprivation of their early experience.
* By age 6, while their physical development had improved, their early experience of deprivation influenced their physical development, with the extent of negative effects depending on how long their children were in the orphanages, their intellectual development followed
* More prolonged damaging effects on the children's social development, the atypical social development was accompanied by abnormal brain activity
* Basic Principle of Childhood Development: the timing of experiences influences their effects