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Atropine
Has many different trade names
Type of anticholinergic
Used for cats, dogs, horses, sheep, and cattle
Adrenergic drug
Causes digestion to stop
Dilates pupils, causes BPM to increase, and more blood flow to skeletal muscles
Fast active
Can be given SQ, IV, IM
Reversal drug includes physostigmine
Used in cases of intestinal obstruction, tachycardia, hypersensitivity
Glycopyrrolate
Generic name Robinul-V
Type of anticholinergic
cholinergic
Can be used in dogs, cats, horses, ferrets, and reptiles
Longer duration than atropine but has a slower start
Used commonly as a pre-anesthetic
Better for C-sections does not cross placental barrier
Used for hypersensitivity, gastrointestinal diseases
Reversal drug Neostigmine
Less likely to cause tachycardia, arrhythmias, and ileus
Preferred drug for rabbits
Amitraz
Brand name Mitaban
it is an antidepressant drug under the category monoamine oxidase inhibitors (MAOI’s)
It is also commonly used as a parasitic treatment
This drug can be toxic in cats or small animals
Certain side effects include could be CNS depression, respiratory depression, bradycardia, and hypotension
Reversal drug yohimbine
Selegiline
Brand name Anipryl
Used in dogs to treat Cushings and cognitive dysfunction syndrome
It can also be used as an antidepressant
Under the class monoamine oxidase inhibitors (MAOIs)
Common side effects include hyperactivity, confusion, and gastrointestinal upset
It increases levels of dopamine to the brain
Fluoxetine
Brand names include Prozac and reconcile
It is a type of antidepressant drug under the class selective serotonin reuptake inhibitors (SSRI’s)
These drugs block the removal of serotonin allowing for more serotonin to remain for longer periods
It is used for the treatment of canine separation anxiety in conjunction with behavior modification plan
it is commonly given in chewable tablets
Common adverse reactions include lethargy, reduced appetite, vomiting, shaking, diarrhea, aggression and potentially seizures
Contradictions include history of seizures, drugs that lower seizure threshold, and hypersensitivity to other SSRIs
Amitryptaline
Brand name Elavil
Used as an antidepressant drug under the class of tricyclics (TCA’s)
Decreases serotonin repute, allows it to accumulate prolongs activity
Used for separation anxiety/general anxiety in dogs, excessive grooming, spaying, and anxiety for cats
Dosage in dogs is 1-4 mg/kg PO q 12hrs
Dosage in cats is 5-10 mg per cat PO once or twice daily
Common side effects are drowsiness, changes in appetite, GI issues, and lethargy
Clomipramine
Brand name clomicalm
It is an antidepressant drug under the class of tricyclics (TCA’s)
Decreases serotonin repute, allows it to accumulate prolongs activity
Helps treat obsessive-compulsive disorders
Male dominance aggression and noise phobias, and separation anxiety
Common dose is 2-4 mg/kg once daily or divides twice daily given PO
Sertraline
Brand name Zoloft
it is an SSRI’s
Used for canine aggression, OCD, anxiety, and spraying in cats
Dog dosage- 2.5-5.0 mg/kg
Cat dosage- 1.0-4.0 mg/kg
For drugs like these to work behavioral modification must also be done
Not a controlled substance
Can be used in dogs, cats, and horses
Paroxetine
Brand name Paxil
It is an SSRI antidepressant agent
Used to treat canine aggression, OCD, anxiety, and spraying in cats
Used in dogs and cats
This drug is specific for serotonin
Potential side effects are vomiting, diarrhea, drowsiness, and decreased appetite
Contradictions of this drug include animals with history of seizures, blood and kidney disorders
Diazepam
Brand name valium
Class IV controlled substance
Used for emergency treatment of status epileptics
Has a short half-life which means it has to be given often
Can be administered orally, injectable, and rectal gel
It is a type of benzodiazepines
Dosage in dogs- 0.5- 2.2 mg/kg
Dosage in cats depends on what behavior you’re looking to treat
Midazolam
Brand name versed
Is a type of benzodiazepines
Used to treat fear, aggression, separation anxiety, OCD, and spraying in cats
new choice of drug for emergency treatment of status epilepticus
It can be used off label or extra label
it comes in forms of injection, suspension, and nasal spray
Side effects include lethargy, vomiting, reduced appetite, and agitation
Contradictions include geriatric patients, or those suffering from liver or kidney disease
Acepromazine maleate
Brand name PromAce
It is an antipsychotic, phenothiazines
Considered a major tranquilizer
Side effects include lethargy, weakness, hyperactivity, high heart rate
Can be given IV, Im, SQ, or orally
Can be used in cats, dogs, and horses
Not a controlled substance
Contradictions include boxer/giant breeds, and sometimes terrier and greyhound breeds
Used as a preanesthetic and tranquilizer for traveling, thunderstorms, and fireworks
levetiracetam
Brand name keppra
It is a newer anticonvulsant drug
Minimal sedative effect, decreased hepatic metabolism
Used to manage epilepsy and seizures
Can be used in dogs, cats, and horses
It is not a controlled substance
Side effects include sleepiness, drooling, decreased appetite, and incoordination
Potassium Bromide
Brand name KBr
Has a long half-life which is measures in days and not hours
It is a type of anticonvulsant
It has been used since the 1800’s
it is mainly used in cases when phenobarbital is not effective alone
Avoid using this drug in cats because it could cause bronchitis
requires 3-5 months to reach equilibrium
Can be used in dogs, horses, and cats if used very cautiously
Phenobarbital
Brand name barbiturate or luminal
Used for long term control of seizures
It is a class IV substance
Common side effects include sedation & ataxia, polyphasic, PU/PD
it is easy for an animal to become tolerant so they may require dosage changes
Can be used in dogs, cats, horses, cattle, ferrets, rabbits, and birds
Commonly used with other medications when phenobarbital alone isn’t enough
Alfaxalone
Brand name Alfaxan
Type of induction drug
Newer anesthetic similar to propofol but with less apnea
Approved for both cats and dogs
Is a class IV controlled substance
Has no analgesia, and can be given IM
Contradictions include hypersensitivity to this drug
Must be administered slowly because it could cause apnea
It is a rapid drug so sedation results happen quickly
Lasts about 25 minutes in dog and 45 minutes in cats
Guaifenesin
Brand name GG
Used primarily in equine medicine as a muscle relaxant
Also relaxes the laryngeal and pharyngeal for easier intubation
It has mild analgesic and sedative effect
Is an excitement-free drug
Not a controlled substance
Contradictions include hypersensitivity and porphyria
Propofol
Brand name PropoFlo 28
A type of drug used for induction
Has a rapid onset and excitement-free stage when given slowly through IV
Has no analgesia
If it is administered to fast it could cause respiratory depression (apnea) in patients
It is a drug you give “to effect” (till you see the medication work)
It is the only white drug given IV
Used in dogs, cats, rodents, rabbits, and snakes
Contradictions include any hypersensitivity and slow recovery with hepatic disease
isoflurane
Brand name Isoflo
One of the most common used general anesthetics in veterinary medicine
Low cost and very stable
Causes only a small decrease in cardiac output
Most animals can be maintained at 1.5% to 2.5%
Is an anesthetic inhalant that must be turned from a liquid to a gas for it to work
Side effects could include hypotension, hypothermia, cardiac and respiratory depression, and nausea/vomitting
Can be used in dogs, cats, horses, cattle, rodents, and reptiles
sevoflurane
Brand name servo-flo
Not a controlled substance
Most commonly used on dogs and horses
it has an extremely rapid induction rate
The best choice for mask and chamber inductions
Has a low odor smell and a is a higher cost than Iso
Animals can be maintained at 2.5% to 4%
Side effects include decreased heart rate, hypotension, and respiratory depression
Has no analgesia
Animals on sevoflurane must be monitored carefully as overdose is easy
Can be used in cats, dogs, horses, cattle, rodents, ducks, and reptiles
doxapram
Brand name Dopram, respiram
Stimulates respiration through the CNS
Reverses respiratory depression from inhalant agents and barbiturates
Administered IV, IM, SQ or sublingual drop for neonates
Repeat injections might be required
Lowers seizure threshold
Emergency dose is 1-5 mg/kg in adults and 1-5 drops in neonates
Contradictions include seizures, heart failure, and hypertension
Can be used in dogs, cats, horses, cattle, rodents, and reptiles
Flumazenil
Brand name Roamzicon
A reversal agent for benzodiazepines
Reverses overdoses or therapeutic effects
Given by rapid IV injection
Has a short half-life, after 1 hour it might need to re-dosed
when used with tricyclics it may cause seizures
Side effects include injection site reactions, and vomiting or ataxia
Contradictions include animals using benzodiazepines, and do not use with tricyclic overdose
Species include dogs and cats
Detomidine
Brand name Dormosedan
Is a alpha-2 agonists
Approved for use as a sedative analgesic in horses
Reversal agent includes tolaoline or antisedan
Has a longer sedation and analgesia than others with 30-90 minutes of sedation and 30-45 minutes of analgesia
Can be given IV or IM
Side effects include increased blood pressure, extra sensitive to sound/stimuli, and bradycardia
Contradictions is horses in shock or organ failure, heart block, CRF, and colic
Can be used in horses, cattle, sheep, and ducks
dexmedetomidine
Brand name Dexdomitor
Is an alpha-2 agonist
Approved to be used in dogs over 12 weeks of age\
Should be given IV, IM, or SQ
Has a greater potency than Xylazine
Other dosages must be reduced when combined with this drug
Reversal drug is atipamezole given IV or IM
Side effects include bradycardia, hypertension, and prolonged sedation effects
Contradictions include young or very old animals, and cardiac, renal, or epileptic disease
Can be used in dogs or cats
xylazine
Brand name Rompun
Is an alpha-2 agonists
Used as a sedative and Analgesic agent, and can be used as an acetic in cats
Can be given IV, IM, SQ, or IP
Reversal drugs include yohimybine, tolazoline, or atipamezole
Side effects include muscle tremors, bradycardia/bradypnea, AV block, and response to auditory stimuli
Contradictions include cattle, who are 10X more sensitive, organ dysfunction/seizures, and do not use with epinephrine
Can be used in cats, dogs, horses, cattle, sheep, rodents, duck, but do not use in pigs
Atipamazole
Brand name Antisedan
Type of alpha-2 agonist
reversal agent: at legal volume of dexomitor given IM
Is a type of sedative or antagonist reversal
Can be given IV, IM, or SQ
Side effects include muscle tremors, vomiting, diarrhea, salivation, and aggression in early stages of recovery
Contradictions include Bradycardia due to dexmedetomidine, consider additional analgesia if it was used to cover pain
Can be used in dogs, cats, horses, cattle, rodents, reptiles, and ducks
Yohimbine
Brand name Yobine
type of alpha-2 agonist
dog/cat reversal agent
Reverses the sedation effects of xylazine within 1-3 minutes of IV administration
Can be given IV, IM, or SQ
Side effects include CNS excitement, muscle tremors, and increased respiratory rates
Contradictions include seizure disorders and renal disease, or hypertension
Can be used in dogs, cats, horses, cattle, pigs, sheep, rodents, rabbits, and ducks
ketamine
Brand name Ketaset
Type of dissociative
Is a class III controlled substance
Often used in combination with other drugs like diazepam, xylazine, acepromazine, and guaifenesin for large animals
When mixed with diazepam it is called KetVal
Can be given IV, IM, or SQ
Side effects include cat’s eyes staying open, hypertension, muscle tremors, hypertonicity, lowers seizure threshold, and apneustic respirations
Contradictions include high doses which can cause respiratory depression, not meant for animals intended for food consumption
Species include dogs, cats, horses, cattle, pigs, sheep, rodents, rabbits, reptiles, turtles, and ducks
Morphine
Morphine is a class II controlled substance
It is a pure agonist with actions at the mu and kappa receptors
It can be used in both cats and dogs but should be used with more caution in cats because it can cause mophine mania
Contradiction includes vomiting
Reversal agent includes naloxone
Can cause histamine release if given too fast IV
Used for visceral and somatic pain
provides analgesia for 2-3 hours with severe pain and 4-6 hours in mild to moderate pain
oxymorphone
Also known as Numorphan
It is an mu agonist
this drug has a greater analgesic potency and sedative effect than morphine, with fewer side effects
Is a class II controlled substance
Analgesia for this drug lasts about 4 hours
Can be used in cats and dogs but not for horses
reversal agent is naloxone
Can be administered IV, IM, and SQ
hydromorphone
Brand name dilaudid
A class II controlled substance
It is an mu agonist opioid
Slightly less potent than oxymorphone but with similar duration of effect
Less expensive than oxymorphone
Can be administered IV, IM, SQ, and epidurally
Can be given to cats and dogs
Potential side effects include vomiting, sedation, lethargy, bradycardia, and dizziness
fentanyl
Brand name Duragesic
Class II controlled substance
It is very potent and has a rapid onset and short duration of effect
Most commonly given as an IV drip or as a skin patch, but also IM and SQ
It can induce sedation, bradycardia, panting, and hypersensitivity
Can be given to cats and dogs
When given in patch form make sure to wear gloves because it is absorb through skin
Used primarily for post-op pain control after major surgeries and chronic severe pain
When wearing patch avoid contact with heating pads it could cause an overdose
butorphanol
Brand name torbugesic or torbutrol
It is a class IV controlled substance
It is an agonist at the mu receptors while an antagonist at the kappa receptors
Can be given IV, IM, SQ, or by mouth
Used for mild to moderate visceral pain, especially cranial abdominal pain in dogs, cats, and horses
Has a short duration of analgesia only around 1 to 2 hours
Produce less sedation than other opioids and less cardiac depression than morphine
Can also partially reverse the effects of other opioids like morphine
buprenorphine
Brand name buprenex
It is a type of analgesic (used for pain control)
a partial agonist, stimulates mu receptors but to less effect than morphine
Can be given IV, IM, by mouth, and topically
Does not provide analgesia for moderate to severe pain inducing procedures
It is a class III controlled substance
Used in cats and dogs
It takes longer to be effective
tramadol
Class IV controlled substance
opioid and serotonin affecting agent
Reversal drug is yohimbine
less addictive, street drug
Not the best pain control, used with another drug usually
Typically given orally with or without food
Mainly used in cats and dogs and has both label and off-label use
Potential side effects include vomiting, diarrhea, lethargy, and bradycardia
naloxone
Brand name Narcan
It is a reversal agent for opioids, the depressant and sedation effect
Dosage for dogs is 0.04 mg/kg IV, IM, or SQ
Dosage for cats 0.05-0.1 mg/kg IV
it is part of the four emergency drugs L.E.A.N
The reversal effects happen within minutes depending on how its given
acetylsalicylic acid
Also known as aspirin
It is a type of NSAID’s
Used in dogs but carefully in cats
Cats do not metabolize aspirin well which could lead to toxicity
Used for analgesic, anti-inflammatory, antipyretic, and anti-platelet effects
Buffered aspirin is preferred to lessen GI effects
Dosage for dogs include 10-25 mg/kg PO every 8-12 hours with food
Dosage for cats 5 mg per cat by mouth every 3 days
phenylbutazone
Brand name Bute
It is a type of NSAID’s
Used mainly in horses but is also approved in dogs
Provides analgesia to mild to moderate pain associated with lameness
Fever reducer
Anti-inflammatory
Used for analgesic, anti-pyretic, and anti-inflammatory properties
Has become less common due to safer and less expensive drugs
Can be administered IV or orally but should never be given IM
flunixin meglumine
Brand name banamine
Used mainly in horses but is approved in cattle and has been used off-label on dogs for parvo
Can only be given IV
If given IM it can be very irritating for the animal
Should be used with caution in dogs as it tends to drop temperature rapidly which could be deadly
Dosage is 1.1 mg/kg IV, PO once daily for up to 5 days
carprofen
Brand name Rimadyl
It is not a controlled substance
Used as an anti-inflammatory and analgesic but it does exhibit some effects on fever
Approved for only in dogs
Safer on the GI system than aspirin
Animals must be monitored for vomiting and diarrhea
Dosage 1 mg/lb by mouth twice a day
Dosage 1-2 mg/lb when given SQ, as appropriate for pain
meloxicam
Brand names include Metacam, Mobic, or laxicam
It is an NSAID
It has fewer side effects than other NSAID’s, GI effects are still possible but only occur occasionally
It is no longer recommended as the main NASID post-op for cats due to the potential for renal toxicity
Dosage for dogs is 0.2 mg/kg PO or SQ as the loading dose
Dosage for cats 0.2 mg/kg PO as an initial dose
Maintenance dose is given at regular intervals to maintain a steady state
acetaminophen
Brand name tylenol
It can be used in dogs at the proper dose but NEVER in cats
In cats it can cause muddy gums
Dogs to not metabolize this drug as well as humans so there are better drugs out there to use
It is only rarely used in vet med
motrin
Brand name Ibuprofen
Should never be used in cats and dogs
It can cause major toxicity including acute renal failure
gabapentin
Brand name is Neurontin
It is not a controlled substance
Used as an analgesic and anticonvulsant
Experimentally used for neuropathic and chronic pain
Can be given in a tablet or capsule form or as a liquid
It is important not to stop this drug abruptly as it could cause withdrawal seizures
Potential side effects include sedation effects and drowsiness
lactated ringer’s (LRS)
This is a type of lsotonic solutions
Type of crystalloid
Contains electrolytes and glucose
Can be used for acute blood volume restoration
Contains lactate and calcium
Don’t use this fluid in the same line as blood or sodium bicarbonate as it could cause a reaction
0.9% NaCl (Sodium Chloride)
Type of isotonic solutions
It is a type of crystalloid
Contains electrolytes and glucose
It is used in shock to increase plasma volume
Also in patients with conditions such as hyponatremia or hypochloremia
Normosol-R
Type of isotonic solutions
As a crystalloid
Balanced electrolyte solution and can also be used for acute blood volume replacement
Contains magnesium byt no calcium
Also contains acetate and gluconate as buffers
50% Dextrose
It is a type of hypotonic solution
Used in cases of hypernatremia, hyperkalcemia, congestive heart failure, and liver disease
It is considered a maintenance fluid as they have less sodium than plasma
Primarily used to supplement existing fluids to a desired glucose concentration
Hetastarch
Also can be known as vet starch
It is a type of colloid
Helps rapidly improves blood pressure
Remains in intravascular space, expands blood volume
30-60% remains in plasma after 24 hours
More expensive
potassium chloride (KCl)
Type of additive
used as a supplement for long-term maintenance fluid therapy
Helps prevent hypokalemia
Fluids containing high dosages of potassium chloride must be given slowly
Given rapidly can kill the patient
sodium bicarbonate (NaHCO3)
Helps regulate hydrogen ion concentration in body fluids
Adverse effects include metabolic alkalosis, hypokalemia, hypocalcemia, and hypernatremia
calcium gluconate (Ca++)
Used as an injection for emergency conditions such as eclampsia, milk fever, and hypocalcemia
Can be diluted with saline but most often isn’t
Must to given slowly to avoid arrhythmia and cardiac arrest
heparin
Type of fluid additive used at high dosages to treat systemic thrombosis and at lower doses for thrombooprophylaxis
L-thyroxine
Also known as Thyrosin
It is a type of systemic endocrine drug
Drug used to treat hypothyroidism
Commonly used in dogs, cats, and horses
Given orally in a form of tablets or capsules
Side effects include increased urination and thirst, vomiting/diarrhea, and hyper activity
methimazole
Also known as Tapazole
It is a systemic endocrine system drug
Used to treat hyperthyroidism
helps increase circulating thyroid hormone
Most commonly used in cats suffering from this disease
regular insulin
Also known as Humulin R
It is a systemic endocrine drug
Used to treat pancreatic disease such as diabetes mellitus
Can be used in other species but most commonly in cats and dogs
Regular insulin is the only type of insulin to be given IV
pimobendan
It is a type of systemic cardiac drug
a positive inotrope and a balanced vasodilator
used to help improve contractility of cardiac muscle fibers
used to treat congestive heart failure in dogs
Side effects include low blood pressure, gastrointestinal upset, nervousness, and kidney failure
epinephrine
Also known as adrenaline
A cardiac systemic drug
it is a type of catecholamines, which is a short term contractility
Used in emergencies of cardia arrest
IT- double the dose
it is usually kept refrigerated
Lidocaine
Type of antiarrhythmic
Drug used to treat Class 1 arrhythmias
Blocks fast sodium channels providing membrane stabilization
Used in cats and dogs
propanolol
Type of antiarrhythmic, systemic rug
Used to treat Class II arrhythmias
Decreases sympathetic input to heart
Beta-adrenergic blocking agent
mannitol
A type of systemic cardiac drug such as a diuretic
It is a drug used to help with fluid build up in the body
Must be kept warm otherwise it crystalizes at room temperature
Used to treat acute conditions such as intracranial and intraocular pressure
furosemide (Lasix/Salix)
Also known as lasix/salix
A type of cardiac systemic drug such as a diuretic
It is a drug used to help with fluid build up in the body
it is the most potent and commonly prescribed diuretic
Commonly used to treat congestive heart failure, lung fluid retention, and certain kidney diseases
enalapril
A type of vasodilator, systemic cardiac drug
This causes blood to flow more easily, reducing the workload of the heart
causes expansion in the diameter of the blood vessels
Used to treat congestive heart failure and kidney disease in cats and dogs
diphenhydramine (Benadryl)
Also known as benadryl
it is a type of antihistamine, respiratory systemic drug
A type of treatment for allergies and respiratory conditions
Adverse side effects include sedation and occasional GI effect
aminophylline
A type of methylxanthines, respiratory systemic drug
This drug is helps to treat against certain toxins an animal could have consumed ex. Chocolates
Used especially in dogs and cats
Relaxes smooth muscles in the airway, making it easier for animals to breathe
apomorphine
It is a type of emetic, induces vomiting
It is the most common choice in dogs
a topical drug placed in the conjunctival sac or parenteral, works rapidly
Class II controlled substance
Flush out eye after vomiting has started
maropitant
Also known as cerenia
Apart of the gastrointestinal systemic drugs
It is an antiemetic, prevents vomiting
it is safer to use with GI obstructions
Commonly used in cats and dogs
Can be given trough injection or tablet form
Famotidine
Also known as Pepcid
Gastrointestinal systemic drug
It is a type of antiulcer medication, reduces the production of stomach acid
Much more potent and has fewer drug reactions than other medications
It is an H2 receptor antagonist
sucralfate
Also known as carafate
It is a type of antiulcer medication, reduces production of stomach acid
used to treat oral, esophageal, gastric and duodenal ulcers
Forms a paste like substance in the stomach which binds to the surface of ulcers
Works best in an acid environment
loperamide
Also known as immodium
A type of antidiarrheal medication
Commonly used in dogs but is okay to use in cats
If this medication isn’t controlled it can cause dehydration, acidosis, weakness and anorexia
metronidazole
Also known as Flagyl
Type of antimicrobial, miscellaneous GI drug
It has some anti-inflammatory properties
Helps treat against infections that can cause diarrhea
Commonly prescribed in dogs
Atropine sulfate (drops)
It is a type of mydriatic/cycloplegic
It is a drug that causes dilation of the pupil, or temporarily paralyzes certain muscles in the eye
Adverse side effects include salivation and contradiction in glaucoma and dry eye
Commonly used in cats, dogs, and horses
This drug helps when examining the eye and during surgery of the lens
pilocarpine
Type of miotics, which is the contraction of the pupil
it is a ophthalmic systemic drug
Can also help stimulate tear production which is helpful in cases of dry eye
It is a treatment for glaucoma
Commonly used in dogs
Proparacaine HCl
Type of Misc Ophthalmic agent
Topical anesthetic
It is an eye numbing agent used in cats, dogs, and horses
Starts working in about 5-10 minutes
Open bottles should be kept refrigerated after
Used for corneal ulcer treatment, foreign object removal, or suture removal
Bacitracin neomycin polymyxin B (BNP)
Type of Anti-microbial
Should not be used in animals intended for food
Used to treat bacterial infections of the eyelid and conjunctiva
Commonly used in dogs and cats
Side effects could include swelling, itching, and potentially burning
Could potentially help with pain
gentamicin sulfate (Otomax)
Type of optic drug
Is a type of antibiotic used to treat ear infections
It is often combined with other drugs
Commonly used in dogs, cats, and horses
Can be given through injection, topical , or orally
It could potentially cause hearing loos so it is not recommended in working dogs ex. police dogs
nystatin neomycin (Panalog)
Type of optic drug
Panalog is a cream or ointment
Helps treat ear infections or inflammation
Commonly used in cats and dogs
Often combined with other drugs
Side effects include a sensitivity to neomycin along with ototoxicity
ivermectin
Also known as ivomec
Type of optic systemic drug
Used to treat ear mites in dogs, cats, and rabbits
Can be used in bovine on extralabel use
Usually given SQ but may be used topically into the ear canal
This is a common drug in heart worm prevention