M3: Clinical Pharmacy - Laboratory Parameters - Part 1 - Urinalysis, Fecalysis, Hematology

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111 Terms

1

Normal urine except:

a. Should be sterile

b. Color: pale yellow

c. pH is 4.5-8 thus generally acidic

d. Specific gravity is 1.002 - 1.030

e. No protein

f. None

f. None

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2

Specific gravity of urine in diabetes mellitus and dehydration.

a. Increased

b. Decreased

a. Increased

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3

Specific gravity of urine in diabetes insipidus.

a. Increased

b. Decreased

b. Decreased

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4

May indicate renal diseases and pre-eclampsia.

a. Protenuria

b. Glucosuria

c. Hematuria

d. Renal Casts

e. Pyuria

a. Protenuria

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5

May indicate diabetes mellitus.

a. Protenuria

b. Glucosuria

c. Hematuria

d. Renal Casts

e. Pyuria

b. Glucosuria

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6

Cardinal signs of DM.

a. Polyuria

b. Polydipsia

c. Weight Loss

d. a and b

e. b and c

f. All

f. All

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7

May indicate renal disease caused by bleeding disorders.

a. Protenuria

b. Glucosuria

c. Hematuria

d. Renal Casts

e. Pyuria

c. Hematuria

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8

May indicate glomerular injury.

a. RBC cast

b. WBC cast

c. Lipid cast

d. Hyalin cast

a. RBC cast

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9

May indicate interstitial or tubular Injury.

a. RBC cast

b. WBC cast

c. Lipid cast

d. Hyalin cast

b. WBC cast

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10

May be caused by proteinuria due to nephrotic syndrome.

a. RBC cast

b. WBC cast

c. Lipid cast

d. Hyalin cast

c. Lipid cast

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11

May be due to dehydration or excessive diuresis.

a. RBC cast

b. WBC cast

c. Lipid cast

d. Hyalin cast

d. Hyalin cast

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12

WBC in urine which indicate infection.

a. Protenuria

b. Glucosuria

c. Hematuria

d. Renal Casts

e. Pyuria

e. Pyuria

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13

Black appearance of stool which indicates upper GI bleeding.

a. Melena

b. Hematochezia

c. Steatorrhea

a. Melena

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14

Red streaks in stool which indicates lower GI Bleed.

a. Melena

b. Hematochezia

c. Steatorrhea

b. Hematochezia

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15

Gray appearance of stool indicating fat malabsorption.

a. Melena

b. Hematochezia

c. Steatorrhea

c. Steatorrhea

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16

Normal RBC in males.

a. 4.3-5.9 million /microliter

b. 3.5-5 million /microliter

a. 4.3-5.9 million /microliter

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17

Normal RBC in females.

a. 4.3-5.9 million /microliter

b. 3.5-5 million /microliter

b. 3.5-5 million /microliter

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18

%RBC in the blood.

a. RBC

b. Hematocrit

c. Hemoglobin

d. Reticulocyte

e. RBC indices

b. Hematocrit

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19

Normal hematocrit in males.

a. 42-52%

b. 37-47%

a. 42-52%

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20

Normal hematocrit in females.

a. 42-52%

b. 37-47%

b. 37-47%

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21

Hematocrit during dehydration.

a. Increased

b. Decreased

a. Increased

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22

Hematocrit during polycythemia.

a. Increased

b. Decreased

a. Increased

Polycythemia - high number of red blood cells

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23

Hematocrit during overhydration.

a. Increased

b. Decreased

b. Decreased

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24

Hematocrit during anemia.

a. Increased

b. Decreased

b. Decreased

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25

Hemoglobin of patient with sickle cell anemia.

a. HbA

b. HbF

c. HbS

d. HbC

c. HbS

HbA - adult hemoglobin

HbF - fetal hemoglobin

HbC - another abnormal hemoglobin (disease)

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26

Normal hemoglobin in males:

a. 13-18%

b. 12-16%

a. 13-18%

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27

Normal hemoglobin in females:

a. 13-18%

b. 12-16%

b. 12-16%

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28

Wintrobe's.

a. RBC

b. Hematocrit

c. Hemoglobin

d. Reticulocyte

e. RBC indices

e. RBC indices

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29

RBC indices include:

a. Mean Corpuscular Volume

b. Mean Cell Hemoglobin oncentration

c. Mean Cell Hemoglobin

d. a and b

e. b and c

f. All

f. All

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30

Normal Mean Corpuscular Volume:

a. 80-100

b. <80

c. >100

a. 80-100

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31

Mean Corpuscular Volume indicating microcytic cell:

a. 80-100

b. <80

c. >100

b. <80

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32

Mean Corpuscular Volume indicating macrocytic cell:

a. 80-100

b. <80

c. >100

c. >100

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33

Normal Mean Cell Hemoglobin.

a. 26-34

b. 31-37

a. 26-34

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34

Normal Mean Cell Hemoglobin Concentration.

a. 26-34

b. 31-37

c. <31

d. >37

b. 31-37

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35

Hypochromic:

a. 26-34

b. 31-37

c. <31

d. >37

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36

Hyperchromic:

a. 26-34

b. 31-37

c. <31

d. >37

d. >37

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37

Immature RBCs.

a. RBC

b. Hematocrit

c. Hemoglobin

d. Reticulocyte

e. RBC indices

d. Reticulocyte

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38

Reticulocyte count in hemolysis or blood loss.

a. Increased

b. Decreased

a. Increased

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39

Normal WBC:

a. 4000-11000 cell/mcL

b. 5000-1100 cell/mcL

a. 4000-11000 cell/mcL

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40

WBC include the following except:

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

f. None

f. None

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41

Increased in bacterial infection and necrosis.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

a. Neutrophils

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42

Increased in viral infection.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

b. Lymphocytes

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43

Increased in TB and endocarditis.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

c. Monocytes

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44

Increased in parasitic infection and acute allergic reactions.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

d. Eosinophils

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45

Increased in leukemia and hypersensitivity reactions.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

e. Basophils

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46

Decreased in fungal infection and inflammation.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

a. Neutrophils

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47

Decrease in debilitating infection, AIDs.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

b. Lymphocytes

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48

50-70% of WBC.

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

a. Neutrophils

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49

20-40% of WBC

a. Neutrophils

b. Lymphocytes

c. Monocytes

d. Eosinophils

e. Basophils

b. Lymphocytes

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50

Normal platelets:

a. 4000-11000 cell/mcL

b. 5000-1100 cell/mcL

c. 150,000-300,000 cell/mcL

d. 200,000-400,000 cell/mcL

c. 150,000-300,000 cell/mcL

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51

Platelets in anemia.

a. Increased

b. Decreased

a. Increased

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52

Platelets in viral infection especially of the flaviviruses.

a. Increased

b. Decreased

b. Decreased

Flaviruses include Dengue Virus, Chikungunya Virus

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53

Erythrocyte Sedimentation Rate during inflammation and infection.

a. Increased

b. Decreased

a. Increased

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54

Erythrocyte Sedimentation Rate during necrosis and malignancy.

a. Increased

b. Decreased

b. Decreased

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55

Monitoring for heparin use and reflects the intrinsic pathway of clotting.

a. Activated Partial Thromboplastin Time (APTT)

b. Prothrombin Time (PT)

a. Activated Partial Thromboplastin Time (APTT)

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56

Normal Activated Partial Thromboplastin Time (APTT):

a. 20-30 seconds

b. 30-40 seconds

b. 30-40 seconds

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57

Decrease in APTT cause:

a. Clotting

b. Bleeding

a. Clotting

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58

Monitoring of warfarin and reflects the extrinsic pathway of clotting.

a. Activated Partial Thromboplastin Time (APTT)

b. Prothrombin Time (PT)

b. Prothrombin Time (PT)

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59

Normal Prothrombin Time (PT).

a. 11-13.5

b. 2-3

a. 11-13.5

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60

Normal Prothrombin International Normalized Ratio (INR) during warfarin therapy.

a. 11-13.5

b. 2-3

c. 2.5-3.5

b. 2-3

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61

Normal Prothrombin International Normalized Ratio (INR) in patient with prosthetic heart valves.

a. 11-13.5

b. 2-3

c. 2.5-3.5

c. 2.5-3.5

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62

High PT International Normalized Ratio (INR) will lead to:

a. Clotting

b. Bleeding

b. Bleeding

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63

Hematopoiesis is the synthesis of all cellular blood components which involve which organs?

a. Bone marrow

b. Spleen

c. Both

d. None of these

c. Both

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64

Essential hormones and vitamins for hematopoiesis.

a. Fe2+

b. B6, B9, B12

c. Erythropoietin

d. a and c

e. All

e. All

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65

Vitamin B essential for hematopoiesis except:

a. B5

b. B6

c. B9

d. B12

e. None

a. B5

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66

Erythropoietin is produced in the:

a. Spleen

b. Liver

c. Kidney

d. Hypothalamus

c. Kidney

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67

Thrombopoietin is produced in the:

a. Spleen

b. Liver

c. Kidney

d. Hypothalamus

b. Liver

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68

Important in decarboxylation.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

a. Vitamin B1: Thiamine

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69

Important for redox reactions.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

f. Two of these

f. Two of these

Vitamin B2: Riboflavin

Vitamin B3: Niacin

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70

Important for CoA.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

d. Vitamin B5: Pantothenic acid

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71

Important for transamination.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

e. Vitamin B6: Pyridoxine

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72

Important in carboxylation.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

b. Vitamin B7: Biotin

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73

Vitamin H.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

b. Vitamin B7: Biotin

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74

Important in 1C transfer.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

c. Vitamin B9: Folate

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75

Important in metabolism of odd numbered C fatty acids.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

d. Vitamin B12: Cobalamin

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76

Important in heme synthesis.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

d. Vitamin B12: Cobalamin

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77

Deficiency in this vitamin lead to cheilosis.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

b. Vitamin B2: Riboflavin

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78

Deficiency in this vitamin lead to Beri-beri.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

a. Vitamin B1: Thiamine

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79

Deficiency in this vitamin lead to Pellagra (Diarrhea, Dermatitis, Dementia).

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

c. Vitamin B3: Niacin

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80

Deficiency in this vitamin lead to Burning Foot Syndrome.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

d. Vitamin B5: Pantothenic acid

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81

Deficiency in this vitamin lead to peripheral neuropathy.

a. Vitamin B1: Thiamine

b. Vitamin B2: Riboflavin

c. Vitamin B3: Niacin

d. Vitamin B5: Pantothenic acid

e. Vitamin B6: Pyridoxine

e. Vitamin B6: Pyridoxine

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82

Deficiency in this vitamin lead to alopecia.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

b. Vitamin B7: Biotin

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83

Deficiency in this vitamin lead to anemia in adults and spina bifida in fetus.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

c. Vitamin B9: Folate

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84

Deficiency in this vitamin lead to megaloblastic anemia.

a. Vitamin B6: Pyridoxine

b. Vitamin B7: Biotin

c. Vitamin B9: Folate

d. Vitamin B12: Cobalamin

d. Vitamin B12: Cobalamin

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85

Anemia caused by deficiency in vitamin B9 and B12.

a. Macrocytic

b. Microcytic

c. Normocytic

a. Macrocytic

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86

Sickle cell anemia and thalassemia.

a. Macrocytic

b. Microcytic

c. Normocytic

b. Microcytic

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87

Anemia caused by iron deficiency.

a. Macrocytic

b. Microcytic

c. Normocytic

b. Microcytic

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88

Anemia caused by CKD, hemolysis, or blood loss.

a. Macrocytic

b. Microcytic

c. Normocytic

c. Normocytic

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89

Aplastic anemia.

a. Macrocytic

b. Microcytic

c. Normocytic

c. Normocytic

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90

Anemia can be due to the following except:

a. Hypoproliferation of RBC

b. Defective nuclear maturation of RBC

c. Increased destruction of RBC

d. Abnormal production of RBC

e. None

e. None

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91

RBC hypoproliferation may be due to tue following except:

a. Bone marrow failure

b. Renal failure

c. Iron deficiency

d. Inflammatory block in chronic diseases

e. None

e. None

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92

Chloramphenicol and phenylbutazone may lead to:

a. Bone marrow failure

b. Renal failure

c. Iron deficiency

d. Inflammatory block in chronic diseases

a. Bone marrow failure

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93

Causes aplastic anemia due to nitroreduction.

a. Chloramphenicol

b. Phenylbutazone

a. Chloramphenicol

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94

Causes pancytopenia or loss of all components of blood.

a. Chloramphenicol

b. Phenylbutazone

b. Phenylbutazone

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95

Most sensitive marker of Fe deficiecy

a. Hemoglobin

b. Ferritin

c. Transferrin

d. Erythropoietin

b. Ferritin

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96

Defective nuclear maturation may be due to:

a. Folate deficiency

b. B12 deficiency

c. Fe deficiency

d. a and b

e. b and c

f. All

d. a and b

Folate deficiency

B12 deficiency

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97

Decrease intrinsic factor.

a. Megaloblastic anemia

b. Pernicious anemia

b. Pernicious anemia

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98

B12 deficiency.

a. Megaloblastic anemia

b. Pernicious anemia

a. Megaloblastic anemia

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99

Autoimmune disease attacking parietal cells.

a. Megaloblastic anemia

b. Pernicious anemia

b. Pernicious anemia

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100

Increased destruction of RBC may be due to:

a. G6PD Deficiency

b. Autoimmune disease

c. Both of these

d. None of these

c. Both of these

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