Tertiary structure shapes and domains

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11 Terms

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Types of Shapes

  1. Helix loop helix

  2. Beta alpha beta unit

  3. Hairpin

  4. Greek key

  5. Beta meander

  6. Alpha Beta barrel

<ol><li><p>Helix loop helix</p></li><li><p>Beta alpha beta unit</p></li><li><p>Hairpin</p></li><li><p>Greek key</p></li><li><p>Beta meander</p></li><li><p>Alpha Beta barrel </p></li></ol><p></p>
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Domains (3)

  1. Independently folded units in tertiary structure

  2. Assemblage of structural motifs

  3. Stable and function

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Domain definition

Associated with specific function. Low binding of structure into enzyme

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Independently folded units in tertiary structure

independant structures

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Assemblage of structural motifs

Parts of secondary come together

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Examples of domains

  • Nucleotide Binding domain

  • Sushi domain

  • Kringle domain

  • Epidermal Growth Factor Domain

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Nucleotide Binding domain

3D section/ shape that allows binding of nucleotide

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Sushi domain

Protein Protein binding

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Kringle domain

Protein Protein binding

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Epidermal Growth Factor Domain

Protein shape and form for proteins on surface of cell allowing cell to interact with enviorment

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Domains that do the same thing

  • Domains that do the same thing (EX: neurotransmitters), like binding ligands, functionally of domains is similar, and aa has a similar shape and pattern. 3D shape close to same.

  • It allows us to assign functions if we find a new protein. Can help determine function manually