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plasma
clear, straw-colored liquid appearing after blood has been centrifuged
formed elements
dark-red and buff-colored portion appearing after blood has been centrifuged. includes red blood cells, white blood cells, and platelets
erythrocytes
red blood cells. small, anucleate biconcave cells containing hemoglobin, used to transport oxygen and carbon dioxide in blood
leukocytes
white blood cells. nucleated cells typically larger than RBCs, attack pathogens and other foreign substances in body. five kinds divided into two categories: granular and agranular.
thrombocytes
platelets. formed in red bone marrow from megakaryocytes. protect the body by forming a platelet plug to stop bleeding when blood vessels rupture and by secreting chemicals that aid in blood clotting.
polycythemia
an abnormally high number of RBCs
anemia
unusually low number of RBCs
granular leukocytes
have discernible vesicles (granules) in cytoplasm that can be seen after staining. include neutrophils, eosinophils, and basophils.
agranular leukocytes
have granules but cannot be observed with light microscope. include lymphocytes and monocytes.
neutrophils
phagocytes that engulf and kill bacteria and other pathogens, aid in resolution of infections, and are first WBCs to arrive at infection site.
eosinophils
neutralize the effect of histamine in allergic reactions, phagocytize antigen-antibody complexes, and destroy certain parasitic worms.
basophils
release histamine, heparin, and seratonin. these chemicals intensify the inflammatory response and are involved in allergic reactions.
lymphocytes
involved in immune responses and include B cells, T cells, and natural killer cells.
monocytes
in tissues, differentiate into macrophages, phagocytes that engulf most of the invading bacteria, viruses, and fungi, as well as dead cellular debris.
thrombocytopenia
is a deficiency in number of circulating platelets.
hematocrit
percentage of blood volume occupied by RBCs. formula is length of RBC’s in mm divided length of the whole column in mm multiplied by 100.
coagulation
process of blood clotting
agglutination
blood clots formation
type A blood
plasma membranes of RBCs have only A antigen present
type b blood
have only B antigens present
type AB blood
have both antigens A and B present
type o blood
do not have either A or B antigen present
Rh positive
have the RH antigen on surface of RBC plasma membrane
Rh negative
do not have Rh antigen
hemolytic disease of the newborn
during delivery baby’s blood can leak from placenta into mother’s bloodstream, causing mother’s body to make anti-Rh antibodies. first baby would not be affected, but following pregnancies with Rh positive fetuses can result in small anti-Rh antibodies crossing placenta and causing hemolysis in fetuses’ blood.
RhoGAM
Rh negative mothers are typically given this so they will not make anti-Rh antibodies.
sickle cell anemia
characterized as a group of inherited red blood cell disorders. have abnormal hemoglobin in red blood cells. abnormal hemoglobin forms stiff rods within red blood cell, changing it into a crescent, or sickle shape. sickle-shaped cells are not flexible and can stick to vessel walls, causing a blockage that slows or stops blood flow, preventing oxygen from reaching nearby tissues.
polycythemia
disease state in which hematocrit is greater than 55%. blood becomes too thick which can impede blood flow.
lymphocytic leukemia
increased lymphocytes
infectious mononucleosis
lymphocytes are reactive and atypical because they are larger. cytoplasm tends to be indented by surrounding RBCs.
eosinophilia
increased number of eosinophils. several causes are known, with most common being some form of allergic reaction or parasitic infection.
acute granulocytic leukemia
increase in granulocytes and band cells
monocytic leukemia
a type of myeloid leukemia characterized by a dominance of monocytes. monocytic cells are predominantly monoblasts.