Top Hospital Drugs

Glucagon

Glucagon

Hypoglycemia

Hypoglycemia Antidote

1 mg IM/IV/SubQ for one dose; may repeat in 15 minutes as needed

Narcan

Naloxone

Opioid reversal

Opioid Antagonist

0.4 to 2 mg every 2 to 3 minutes up to 10 mg (IV preferred) *IV/IM/Intranasal

Sublimaze

Fentanyl

Pain

Opioid agonist

1-10 mcg/kg IV bolus, with/without 1-2 mcg/kg/hr IV infusion following bolus

Dilaudid

Hydromorphone

Pain

Opioid agonist

IR (PO): 2 to 8 mg every 4 to 6 hours as needed. IV: 0.5 to 3 mg/hour

Cerebyx

Fosphenytoin

Epilepsy

Anticonvulsant

LD: 15 to 20 mg PE/kg, then 4 to 6 mg PE/kg/day *Therapeutic Drug Monitoring

Zofran

Ondansetron

Nausea/Vomiting

Selective 5-HT3 Receptor Antagonist

PO/IV: 4 mg to 8 mg every 8 hours

Decadron

Dexamethasone

Inflammation

Corticosteroid

IV/IM/intrasynovial; dose varies dependent on indication

Medrol, Solu-Medrol

Methylprednisolone

Inflammation

Corticosteroid

PO/IV/IM dosing

Mycamine

Micafungin

Fungal infection

Antifungal

IV

Vancocin

Vancomycin

Infection

Antibiotic-Glycopeptide

15 - 20 mg/kg/dose IV every 8 - 12 hours

Gentamicin

Gentamicin

Infection

Antibiotic - Aminoglycoside

Weight-based dosing; use therapeutic drug levels to adjust dose

Levaquin

Levofloxacin

Infection

Antibiotic - Fluoroquinolone

750 mg IV every 24 hours *Renal dose adjustment

Cleocin

Clindamycin

Infection

Antibiotic - Lincosamide

600 mg - 900 mg IV every 6-8 hours (depends on indication)

Zosyn

Piperacillin/Tazobactam

Infection

Antibiotic -

Beta-lactam/Beta-lactamase inhibitor

3.375 grams to 4.5 grams IV every 6 to 8 hours

Teflaro

Ceftaroline

Infection

Antibiotic - Cephalosporin (5th generation)

Maxipime

Cefepime

Infection

Antibiotic - Cephalosporin (4th generation)

1 gram to 2 grams IV every 8 to 12 hours over 30 minutes *Renal dose adjustment

Cefotaxime

Cefotaxime

Infection

Antibiotic - Cephalosporin (3rd Generation)

1 to 2 grams IV every 4-6 hours or every 6-8 hours (depends on indication)

Rocephin

Ceftriaxone

Infection

Antibiotic - Cephalosporin (3rd Generation)

1 to 2 grams IV/IM every 12 to 24 hours

Mefoxin

Cefoxitin

Infection

Antibiotic - Cephalosporin (2nd generation)

1 gram to 2 grams IV every 6 to 8 hours

Ancef

Cefazolin

Infection

Antibiotic - Cephalosporin (1st Generation)

1 to 1.5 grams IM/IV every 8 hours

Merrem

Meropenem

Infection

Antibiotic - Carbapenem

500 mg to 2 grams IV every 8 hours *Renal dose adjustment

Cubicin

Daptomycin

Infection

Antibiotic - Lipopeptide

Weight-based dosing IV *Renal dose adjustment

Zyvox

Linezolid

Infection

Antibiotic - Oxazolidinone

600 mg IV/PO every 12 hours *Drug interaction with MAOIs

Magnesium Sulfate

Magnesium Sulfate

Hypomagnesemia

Magnesium Supplement

*IM/IV/PO dosing; dependent on severity of deficiency

Potassium Chloride

Potassium Chloride

Hypokalemia

Potassium Supplement

IV: 40 to 80 mEq/day; PO: 20 to 40 mEq/day in 1 to 2 divided doses*IV/PO dosing depending on severity of deficiency

Sodium Bicarbonate

Sodium Bicarbonate

Acidosis

Electrolyte Supplement - Alkalinizing Agent

IV dosing: Most commonly dosed at 150 mEq/1,000 mL D5W or IV push of 50 mEq *IV/PO dosing depending on severity of deficiency

Nimbex

Cisatracurium

Intubation

Neuromuscular Blocker

IV infusion

Anectine

Succinylcholine

Intubation

Neuromuscular Blocker

IM/IV

Vecuronium

Vecuronium

Intubation

Neuromuscular Blocker

Weight-based; obese patients > 130% IBW - dose on IBW

Versed

Midazolam

Sedation

Benzodiazepine

IV

Ketalar

Ketamine

Sedation/Pain

General Anesthetic

Weight-based dosing IV/IM

Diprivan

Propofol

Sedation

General Anesthetic

IV infusion*Contraindicated in egg and soy allergy

Precedex

Dexmedetomidine

Sedation

Alpha2-Adrenergic Agonist

Weight-based dosing, IV infusion in mcg/kg/hour

Remicade

Infliximab

Immunosuppressant

DMARD

Weight-based dosing, IV

Cardizem

Diltiazem

Arrhythmia

Calcium Channel Blocker

IV for hemodynamically stable patients. Bolus dose then continuous infusion

Labetalol

Labetalol

Hypertension

Alpha/Beta-Adrenergic Blocker

IV for acute hypertension/hypertensive emergency

Dobutrex

Dobutamine

Acute Heart Failure

Alpha/Beta agonist

2 to 40 mcg/kg/minute IV Continuous Infusion

Adrenalin, EpiPen

Epinephrine

Shock

Alpha/Beta-agonist

IV/IM dosing dependent on indication

Levophed

Norepinephrine

Shock

Alpha/Beta-agonist

Continuous IV infusion

Intropin

Dopamine

Shock

Alpha/Beta Agonist

2-20 mcg/kg/min. Continuous IV infusion; adjust dose every 10-15 min. t achieve desired hemodynamics

Pacerone

Amiodarone

Arrhythmia

Class III Antiarrhythmic

IV infusion*Renal dose adjustment

AtroPen

Atropine

Bradycardia

Anticholinergic

IV/IM/Endotracheal; dosing dependent on indication

Adenocard

Adenosine

Arrhythmia

Antiarrhythmic

6 mg IV/PO x 1, if not effective in 1-2 min, repeat 12 mg IV/PO x 1

Activase, Cathflo

Alteplase

Acute Ischemic Stroke

Thrombolytic

Stroke: Weight-based dosing, IV infusion;

Acute Pulmonary Embolism: 50 mg or 100 mg IV push x 1 dose

Aggrastat

Tirofiban

Acute Coronary Syndrome

Glycoprotein IIb/IIIa Inhibitor

IV infusion

Mephyton

Phytonadione

Warfarin Reversal

Vitamin K

PO/SubQ/IV dosing *Avoid IM dosing

Angiomax

Bivalirudin

Thrombosis Prophylaxis/Treatment

Direct Thrombin Inhibitor

IV Infusion *Renal dose adjustment

Argatroban

Argatroban

Thrombosis Prophylaxis/Treatment

Direct Thrombin Inhibitor

IV infusion *Can falsely increase INR

Heparin

Heparin

Embolism Prophylaxis/Treatment

Unfractionated Heparin

Initial 10,000 Units IV then 50 to 70 Units/kg IV every 4 to 6 hours*Therapeutic Drug Monitoring

Lovenox

Enoxaparin

Embolism Prophylaxis/Treatment

LMWH

VTE (Venous Thromboembolism) Treatment: 1 mg/kg SubQ every 12 hours or 1.5 mg/kg SubQ once daily.

VTE Prophylaxis: 40 mg SubQ once daily. * Renal dose adjustments