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What is brain ablation?
Involves the destruction or removal of a brain part.
Intentionally done
Followed by assessment of subsequent changes in behaviour or mental functioning.
Damaged caused is irreversible
What is brain lesioning?
Involves disrupting or damaging the normal structure/ function of the brain
Term lesion also used generally to refer to any area of damaged
Intentionally done
Followed by assessment of subsequent changes in behaviour or mental functioning
May involve temporary disruption to brain function
What is a lesion, and can it be caused by an ablation?
A lesion may be generally referred to as any area of damaged tissue so therefore it can also be caused by an ablation.
What are the ethics behind brain ablation and lesioning?
Brain ablation or permanent lesioning for an experimental research is considered unethical.
However: may be used to remove a tumour or for debilitating brain-related disorders.
When may a lesion cause temporary disruption?
Provide and example.
When nonsurgical procedures are used.
For example: drugs that are injected into a brain area.
What is an ESB
Electrical stimulation of the brain.
How does an electrical stimulation of the brain (ESB) work?
A small electrified wire (or disc) is inserted or placed onto a specific area of the brain.
The device will then initiate, interfere or inhibit a response,
What are the ethical issues of an ESB?
Extremely invasive
Potentially harmful
risk of physical or psychological harm is unacceptable according to current ethical guidelines
How may an ESB be used ethically?
Used for therapeutic reasons:
help with motor symptoms of Parkinson’s disease.
depression in severe cases
What is a split brain surgery?
Involves the cutting the main band of nerves tissues, the corpus callosum connecting the two hemispheres.
What was Roger Sperry able to demonstrate through his split brain studies?
Demonstrated that the 2 cerebral hemispheres clearly ‘specialise’ in some areas and confirmed contralateral arrangement of the body.
Most Notably: the left hemisphere specialises in language expression and comprehension.
Does movement need both sides of the brain to communicate throught the corpus callsoum?
No.
What is the corpus callsoum?
The main nerve tissues connecting the two cerebral hemispheres.
Main communication pathway for neural images
What is hemispheric specilisation?
The dominance or particular control of each hemisphere on differnet particular tasks
Does only one hemisphere that is specialised in that task function whilst doing thee?
No, they may exert ‘dominance’ over a particular function but both hemispheres are often involved.
Functions of the left hemisphere.
Involved in language and speech
speech comprehension, fluent and coherant speech
Analytical functions:
maths, logic interpreting data
Controls the right side of the body
Functions of the right hemisphere.
Non-verbal
Judgement of rythm and time
Controls left side of the body
Spatial abilites:
constructing puzzles, rotating objects
Processing things as a whole
Detection and expression of emotions
Recognition of faces and patterns
Art apprecitation
Day dreaming and fantasy
2 categories of neuroimaging/brain scanning
Structual and Functional
What is structural imagining?
Refers to techniques that produce images, or scans of the brains anatomy and structure.
What is functional neuroimaging/dynamic neuroimagining
Refers to techniques that provide views of some aspect of brain function by showing images of the brain ‘at work’.
and provide information about brain structure
What is the purpose of functional neruoimagining?
To allow correlations between brain areas that may be active at the time of a participant’s response.
What is CT?
Computerised tomography
How does computerised tomography work?
uses x-ray equipment:
participant may be given substance called contrast
-highlights brains blood vessels
-enables interpretation of resulting images
What does CT do?
scan brain at different angles
shows horizontal cross-section
more detailed than x-ray
can be produced in 3-D
What is the purpose of CT?
useful for locating brain abnormalities/injuries
-Location and size of a tumour
-Extent I've damaged caused by brain injury from stroke/hit
-Brain abnormalities in people with mental health disorders
What are the limitations of computerised tomography?
black-and-white images only
Only shows brain structure (not as well as scanners that do not use x ray equipment)
Not very good for imaging tissue
What does MRI stand for?
magnetic Resonance imaging
How does MRI work?
uses harmless magnetic fields to vibrate atoms in the brain neurons to generate a computer image
How are CT and MRI similar?
both taken in metal cylinder both structural
What is more sensitive CT or MRI?
MRI
Because MRIs are more sensitive than CT, what does this entail?
images are clearer and more detailed
Produced in full colour
-Assist researchers to distinguish between different brain areas/structures
Examples of subtle changes that an MRI can produce
loss of Myelin protecting nerve fibres
Nerve/tissue degeneration
Blood clot/leaks from strokes and injury
What is FMRI?
functional magnetic resonance imaging
What does FMRI do?
Detects and records brain activity by measuring oxygen consumption across brain through standard MRI technology
Why is FMRI preferred in psychology?
can take numerous photos in succession and therefore detect brain change as it occurs can
simultaneous scan the brains of two people as they interact
What does pet stand for?
positron emission tomography
How do pet scans work?
tracks a glucose solution containing short-lived radioactive tracer that is usually injected into the brain
Uses colour code to indicate areas of high and low activity
-looks like a coloured map of someone's brain
Are pet scans functional or structural
functional
What are the limitations of functional neuroimaging?
more or less blood flow does not necessarily mean more or less brain activity
similarly does not mean that a brain area is engaged or not engaged
What is the cerebral cortex?
Covers the cerebrum, outer layer of cerebrum
Involved in high order thinking
-perception, learning, memory, language, problem-solving
What is a motor area?
related to initiating and executing voluntary movements
What is a sensory area?
receive processed information from five senses
-made of sensory neurons
What are association areas?
surround sensory and motor areas
-deal with complex functions
That require integration of information from multiple or different areas
Frontal lobe
Located at the front of this cerebral hemispheres
Associated with voluntary movement, speech production, sophisticated mental abilities, personality, decision making
4 areas of the frontal lobe
prefrontal cortex
Pre-Motor cortex
primary motor cortex
Brocas area
Function of the prefrontal cortex
reasoning planning
problem-solving
decision-making
symbolic thinking
regulation of emotions
expression self-awareness
aspects of personality
plans required motor sequences and send instructions to motor cortexes
primary motor cortex
initiates and controls voluntary movement
contralateral arrangement
amount of cortex devoted to body part corresponds to complexity or fineness of movements
location of primary motor cortex
strip of neural tissues located at the rear of each frontal lobe
function of Boroc’s area
crucial role in production of articulate speech that is clear & influent
coordinates messages to lips, jaws, tongue, vocal cords
function of parietal lobe
receives some processes somatosensory (bodily) information
touch and temperature
information about muscle movement & body position
about the primary tomato sensory cortex
receives and processes somatosensory (bodily) information
touch and temperature
information about muscle movement & body position
what is the amount of cortex in the primary somatosensory cortex represent?
The amount of cortex represents sensitivity
Function of occipital lobe
Almost exclusively devoted to the sense of vision
Explain the contralateral arrangement of the occipital lobe
left half of each eye receives info from the r ½ of visual field and sends information only to the visual cortex in L occipital lobe
Function of primary visual cortex
Neurons within are are specialised to respond to different features of visual infromation
What different features of visual information does the primary visual cortex respond to?
features of orientation
edges
motion
colour
shape
what is the temporal lobe involved with?
auditory perception
speech comprehension
important role in memory
parts of visual perception (recognising faces/objects)
emotional responses to memories/sensory information
what are the distinct regions of the temporal lobe?
wernicke’s area (left side)
primary auditory coretx
why is the primary auditory cortex an example of hemispheric specilistation?
left processes verbal sounds e.g: comprehends language
right side process non-verbal soundse.g: music
What is the function of wernicke’s area?
crucial role in comprehension of speech
involved in production of meaningful and cohernt speech
What is neuroplasticity?
The ability of the brain and other parts of the nervous system to change in response to experience,
includes the brain ability to recover/ compensate for loss of function from injury
where does neuroplasticity change occur?
at a cellular level, typically at the synpase
t/f the brain shape changes during neuroplasticity?
false, brain shape does not change
what may cause neurons to change?
during brain developtment
during learning
certain drugs
in response to injury
how do neurons change during neuroplasticity?
form new neural pathways, with existing neuros, interconnect
what causes the reorganiation of neurons?
base do
when and which areas have the highest plasticity
what is experience dependant plasticity
involves brain change that modifies some part of neural structure that is already present.
depends on exposure to various enviormental experiences that are unique to individual
-may occur during lifetime
-no crucial period
-evident in everyday life
what is the end result after brain injury?
brain function lost through injury is rerouted via new connections
what is brin injury?
any type of brain damage or disorder that impairs/ interferes with normal functioning, either temporarily or permanently
acquired brain injury
temrn most commonly used in realtion to damage or disorders that occur after birth
sudden onset
occurs abruplty
insidious onset
gradually develops
what is traumatic brain injury?
type of brain injury that occurs when external force causes damage to brain
what may happen to neurons from a traumatic brain injury
may be killed outright
or slowly starved of oxygen & nutrients
what is asphsia?
language disorders that results from acquired brain injury
fluent aphasia
speech is easily produced and flows freely but sentences do not make sense
person usually has difficulties understanding what is heard/said
non fluent aphasia
difficulty speaking clearly, often in short sentences
pure aphasia
specific impairments in reading ,writing or recognising spoken words
broca’s aphasia
damage to broca’s area
considerable difficulty producing speech
+reading and writing impaired
aware of language difficulties
difficulty understanding complex speech, understand everyday conversation
wernicke’s aphasia
considerable difficulty understanding spoken, written language and speaking in a meaningful way
What is a stroke
occurs when blood supply to part of the brain is interrupted
what are the two types of strokes
ischemic, haemorrhagic
what are ischaemic strokes?
when blood supply is restricted/stopped in 1 blood vessel because its blocked
typically caused by blood clot forming somewhere else and travelling up
what are hemorrhagic strokes?
when a blood vessel supplying the brain becomes weak and bursts
causes bleeding in the brain
what typically causes hemorrhagic strokes?
high blood pressure
Risk factors of strokes that cannot be controlled
older age
male
family
history
already experinced a stroke
Factors that can be controlled that contribute to the likelihood of a stroke
high cholesterol
high blood
smoking
overweight/obese
lack of exercise
drugs/alchol
door diet(too much saturated fats/too salty)
what is the effect of a stroke?
During a stroke neurons within the brain may die due to lack of oxygen and nutrients.
Symptoms of a stroke
•numbness or weakness in the face, arm or leg, especially on one side of the body
•speech disturbance, such as slurring or decreased speech fluency or comprehension
•trouble walking, dizziness, loss of balance or lack of coordination
•trouble seeing in one or both eyes
•headache, usually severe with no known cause
•difficulty swallowing
•nausea or vomiting.
Explain the effects of a stroke
the effects of a stroke will be different for all, as the impact will be based off of the:
location, amount of neurons that die, time of deprevation
if the cerebellum was impacted by a stroke what would it cause?
codination issues
if the pons, thalamus, was affected during a stroke what would happen?
Permanet coma
if the hypothalamus was effected during stroke
body temp & sleep regulation become irregular
Motor cortex damage in the right hemisphere
paralysis on L side of body