Indications and Contraindications (Acne, Hematopoietic Agents, Anticoagulants, Antibacterials: Penicillins, Cephalosporins, Carbapenems, Macrolides, Fluoroquinolones)

What are the indications for topical acne products (excluding tacrolimus, pimecrolimus, and ivermectin)?

Topical treatment of acne vulgaris

What are the indications for isotretinoin?

Treatment of severe nodular/inflammatory acne vulgaris

What are the indications for tazarotene?

Treatment of acne vulgaris, treatment of psoriasis and premature aging

What are the indications for tacrolimus and pimecroliumus?

treatment and maintenance of atopic dermatitis

What are the indications for ivermectin?

Treatment of inflammatory lesions of rosacea in adults (18 and older)

What are the indications for topical brimonidine?

Treatment of facial erythema of rosacea in adults (greater than 18)

What are the contraindications to acne/facial agents (all)?

Hypersensitivity

What are the contraindications to adapalene?

eczema, seborrheic dermatitis

What are the contraindications to tretinoin?

pregnancy, lactation

What are the contraindications to isotretinoin?

Pregnancy, lactation, hepatic and renal insufficiency, elevated blood lipid values, patients taking tetracyclines

What are the indications for iron supplementation?

prevention and treatment of iron deficiency anemia

What are the contraindications to iron supplementation?

hemosiderosis and hemochromatosis

What are the indications for folic acid supplementation?

folate deficiency anemias and prevention of fetal malformations prior to and during pregnancy

What are the indications for cyanocobalamin?

prevention of vitamin B12 deficiency

What are the indications for anticoagulation therapy?

Prophylaxis and treatment of venous thromboembolism

What are the contraindications to rivaroxaban and dabigatran?

Renal insufficiency and in combination with CYP3A4 and P-glycoprotein

What are the contraindications to low molecular weight heparins?

patients with a history of heparin induced thrombocytopenia (HIT)

What should be considered when using low molecular weight heparins, but is not considered a contraindication?

renal dysfunction

What are the contraindications to unfractioned heparins?

Patients with a history of heparin induced thrombocytopenia (HIT)

What are the contraindications to warfarin?

pregnancy, patients with hemorrhagic tendencies, blood dyscrasias and malignant hypertension, as well as many significant drug interactions

What are the indications for penicillins?

Infections caused by susceptible bacteria in the upper respiratory tract (otitis media), lower respiratory tract (bronchitis), skin, bone, and many other tissues.

What are the contraindications to penicillins?

hypersensitivity to penicillins

What are the indications to cephalosporins?

Infections caused by susceptible bacteria in the upper respiratory tract (otitis media), skin, urinary treat and other tissues

What are the contraindications to cephalosporins?

Patients with hypersensitivity to cephalosporins

What should be considered when treating with cephalosporins, but is not considered a contraindication?

Patients with allergies to penicillins (risk of cross-reactivity)

What are the indications for carbapenems?

Susceptible bacteria in the lower respiratory tract, urinary tract, intra-abdominal cavity and other tissues

What are the contraindications to meropenem?

allergies to beta lactams

What are the indications for macrolides?

Susceptible bacteria in the upper and lower respiratory tract, genitourinary tract, skin, and other tissues.

What are the indications for clarithromycin?

Susceptible bacteria in the upper and lower respiratory tract, genitourinary tract, skin, and other tissues.

Also used in combination with other medications for H pylori eradication in peptic ulcer disease

What are the contraindications to macrolides?

Hypersensitivity

What are the contraindications to clarithromycin?

Patients taking pimozide, ergotamine, or dihydroergotamine

What are the indications for fluoroquinolones?

Susceptible bacteria in the upper and lower resp tract, urinary tract, skin, prostate (cipro only), and other tissues

What are the contraindications to fluoroquinolones?

Hypersensitivity to fluoroquinolones, benzalkonium chloride (eye drops only)

What are the contraindications to ciprofloxacin?

Patients taking tizanidine