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Neoplatonism
The universe is interconnected and there is no distinction between living & nonliving things; plastic force
Glossopetra
("tongue stones"), were fossilized giant shark teeth taken from limestone deposits; used by magicians and was believed to come from Heaven
Aristotelianism
The difference between living and nonliving is more distinct and includes spontaneous generation
Nicolas Steno
Laws of Superposition, Original Horizontality, and Lateral Continuity; Shark direction disproves glossopetrae
Low Probability of Fossilization
Soft organisms: slug
Small parts: star fish
High Probability of Fossilization
Hard organisms
Big parts
Carl Linnaeus
Hierarchical classification of animals/animal kingdom
Prokaryote
no nucleus, Archaea and Bacteria
Eukaryote
has nucleus, Eukarya
James Hutton
Father of Western Geology, importance of angular unconformities
Uniformitarianism
Things today can be used to infer the past, some processes that occur today have always operated in the past and will continue to operate in the future.
Charles Lyell
Uniformity in nature, empiricism and observation
George Cuvier
Vertebrate paleontology, subordination of characters
Correlation of Parts
animals/vertebrates are machine-like and ordered, body shows purpose, comparative anatomy
Subordination of Characters
all traits are important to an organisms survival, comparative anatomy
Comparative Anatomy
the study of similarities and differences between living and fossil organisms.
Jean Baptiste Lamarck
Studied invertebrates, extinction of lineages does not happen, organisms continue increasing complexity until reaching ideal perfection
Homologous Structures
shared similarities in structures that are not necessary
Analogous Structures
functionally similar structures that are constructed differently
Vestigial Structures
structures with no apparent purpose, often reduced in size
William Smith
Faunal succession and geological time (geological map of England)
Faunal Succession
fossils are consistent within strata, showing its age
Charles Darwin
Origin of coral reef atolls, Survival of the Fittest, Origin of Species
Allometric Growth
Shaped change, differences between juvenile and adult forms
Isometric Growth
Proportions are relatively the same throughout development
Heterochrony
changes in timing of developmental events
Heritability
predictability of traits from one generation to the next being transferred
Geographic variation
morphologically different from place to place, isolation, small population
Temporal variation
morphologically different over time in the same region
Density-Independent Checks on Population Growth
checks that are not impacted by population density, natural disasters
Density-Dependent Checks on Population Growth
checks that are affected by population density, disease
Logistic Growth
Increase in population until it reaches carrying capacity
Variability
Offspring are not exact copies of parents
Heritability
Traits passed to offspring
Differential Reproductive Success
Individuals with advantages contribute to more successful offspring
Fitness
Relative ability of an individual to reproduce and contribute offspring to the next generation
Directional Selection
Over time the population move along with fitness
Stabilizing Selection
Fitness is average and common
Disruptive Selection
Increase extremes, two distinct populations form
Drift
No heritability, completely random selection
Phenotype
Physical expression of traits
Genotype
Genetic makeup that determines phenotype using two alleles from each parent
Homozygote
two copies of the same allele
Heterozygote
one dominant and one recessive allele
Incomplete Dominance of Alleles
Both alleles of a gene are partially expressed, an intermediate
Co-Dominance of Alleles
Equal expression of alleles
Pleiotropism
one generation where a single gene influences multiple phenotypic traits
Epistasis
the effect of a mutation is dependent on genetic background
Ecopheqotypic variation
interaction of genes and the environment, one set of genes with many possible outcomes
Chromosomes
location of alleles and hereditary materials, humans have 23 pairs
DNA
deoxyribonucleic acid, fixed composition, sugar and phosphate with nitrogenous base
Purines
Adenine and Guanine
Pyrimidines
Thymine and Cytosine
Helicase
unzips double stranded DNA
Primase
generates short strands of RNA to initiate DNA synthesis
DNA Polymerase
adds to the 3-prime end, replicating the leading strand and assembling new strands
Point Mutation
mistake made during replication
Proteins
chemical compounds, single linear chain of amino acids
R-groups
determine protein shape and function
RNA polymerase
synthesizes RNA strands from DNA strands
RNA
Ribonucleic acid, hydroxyl group on 2-prime
Pyrimidines (RNA)
Uracil and Cytosine
mRNA
messenger, basic info for sequencing amino acids
Ribosome
coordinate the interaction between mRNA and tRNA to make amino acid chains (proteins)
tRNA
transfer, RNA with double and single stranded regions
Codon
3 base sequence identifying 1 of 20 amino acids
Insertions and deletions
slippage during replication, causes addition or deletion of bases, shorter or longer strands
Gene
regions of DNA that are transcribed and translated
Exons
directly translated, determine sequence of amino acids in proteins
Introns
untranslated pieces of DNA between exons, removed after making RNA
Reverse transcription
transfer into from RNA back to DNA, retroviruses (HIV)
Regulation of gene expression
extent to which genes are transcribed into functional mRNA to proteins
Transcription factors
proteins that regulate gene expression via transcription
Specificity factors
affect affinity of RNA polymerase for specific promoters for a gene on the DNA strand
Activators
recruit RNA polymerase to the promoter gene to increase expression
Repressors
bind to non-coding portions of DNA near or on promoters, interfere with RNA polymerase and prevent transcribing
Chromatin
complex of DNA and proteins, compact structure of chromosomes in eukaryotes
Open chromatin
allows RNA polymerase access and facilitates gene expression
Pre-transcription
before mRNA formation, controlling RNA polymerase, inhibit/promote transcription, regulate amount of transcript produced
Post-transcription
interception of mRNA prior to transition into protein in a ribosome, prevent expression
Pluripotent Cells or Cell Fate
cells can become anything if given the right signals, stem cells
Homeobox Genes
code for transcription factors that initiate a regulatory cascade of gene expressions during developments that determine cell fate and differentiation, used to make mRNA and proteins
Morphogenetic Mutations
individuals that display abnormal or altered patterns of development
Antennapedia Mutant
In fruit flies, anteriorly causes segment identity to be confused
Ultrabithorax Mutant
Wings and legs in insects, homozygous for reduced function of alleles,
Hox Gene
a group of genes critical for the development of the body plan
Viruses
a protein coating surrounding nucleic acids and proteins that infect living cells to reproduce
Synonymous Mutation
DNA changes that do NOT affect the protein sequence, environmentally neutral and functionally silent, cannot be removed from populations by natural selection
Non-synonymous Mutation
change protein sequences, subjected to natural selection
Genetic Switches
small segments of DNA that do not code for proteins that affect recruitment of RNA polymerase (pre-transcription regulation), turn on and off the genes that are expressed
Mitosis
cells replicates chromosomes and segregates them, producing two identical nuclei to prepare for cell division
Meiosis
type of cell division where the number of chromosomes in gametes (sex cells) is reduced, produces gametes
CRISPR
harnessing bacterial viral defense mechanisms for genetic engineering
Species
groups of interbreeding populations that are reproductively isolated from other groups
Reproductive isolation
continuity of information between generations, permits local adaptation and/or drift to result in divergence, allows natural selection (think Hawai'i!)
pre-zygotic isolation
union of egg and sperm never occurs, does not permit viable fertilization, caused by differences in number of chromosomes or chemical signals
temporal isolation
peaks of sexual activity in different populations/species do not overlap in time to reproduce
behavioral isolation
different displays and rituals like mating calls