MMiPeople Francesco Redi: scientist who tested spontaneous generation with rotting meat and maggot formation with an open container, sealed container, and gauze-covered container, and refuted spontaneous generation Needham: scientist who tested spontaneous generation with boiling chicken broth, sealing the container, and waiting a few days to assess for microbial growth, and supported spontaneous generation Spallanzani: scientist who tested spontaneous generation with further testing, Needham’s experiment, and tested with an open and closed container that was later opened, and refuted spontaneous generation Louis Pasteur: scientist who used swan-neck flasks in his experiment and definitively refuted spontaneous generation Anthony van Leeuwenhoek: scientist who was the first to observe eukaryotic microbes, calling them “wee animalcule” Robert Hooke: coined the term “cell” when looking at cork Matthias Schleiden: observed cells in plant tissue Theodor Schwann: observed cells in animal tissue Rudolf Virchow and Robert Remark: observed cells dividing to make new cells (not mitosis) Hippocrates: suggested disease has natural causes Thucydides: advocated for evidence-based analysis of cause and effect and suggested immunity after observing plague survivors didn't get sick again Marcus Terentius Varro: the first to propose that things we cannot see cause disease Ignaz Semmelweis: physician who observed the spread of disease among patients in different sides of the hospital and instituted hand washing between patients to reduce the spread of disease from patient to patient via healthcare workers Joseph Lister: surgeon who observed post-surgical infection and instituted hand washing and sterilization of medical equipment with 5% phenol solution for less disease Robert Koch: scientist who developed Koch’s postulates to determine the cause of disease and had a rivalry with Louis Pasteur John Snow: questioned the London cholera outbreak and asked questions to the people who had been infected about where they had been and what they had eaten or drank, and noticed that everyone who had cholera used one of two water pumps Classification of microbes What are the 2 domains that are composed of all microbes? Bacteria and Archaea What domain of life is composed only of some microbes? Eukarya What types of microbes do not fit into the domains of life? Viruses and Prions Prions: unicellular organisms in the domains Bacteria and Archaea with no nucleus and have cell walls Viruses: acellular and domainless (not alive) Eukaryotes: unicellular OR multicellular organisms, in domain Eukarya, have a nucleus, have membrane-bound organelles, and include fungi, algae, protazoa, and helminths How many times bigger are bacteria than viruses? 100x A cell is around how many times bigger than an individual bacteria? 10x Cell structures Know the function, general location, and whether they are shared with eukaryotes (if yes similarities/differences) of the following structures: 1. Nucleoid: contains chromosome(s) and nuclear-associated proteins that are usually haploid and circular near the center of the cell, which hold the DNA genetic information without a membrane Eukaryotes = have a nucleus, are diploid and linear Prokaryotes = have nucleoid, are haploid and circular 2. Ribosomes: work with mRNA protein synthesis, made up of proteins and RNA, found in cytoplasm Eukaryotes: 80S, 60 large, 40 small (18S sequencing) Prokaryotes: 70S, 50 large, 30 small (16S sequencing) 3. Cytoplasm: fluid inner layer 4. Fimbriae: short, bristle-like projections for attachment to surfaces 5. Endospores: not all bacteria have, protect bacteria in a dormant state/ harsh environment, found inside bacteria, sporulation = the process of becoming dormant, germination = process of becoming active 6. Plasma membrane: semipermeable, composed of lipids and proteins, controls transport into and out of cell, most inner layer before cytoplasm (ex: facilitated diffusion, active transport, diffusion, endocytosis (Eukaryotes), sterols (Eukaryotes), and cholesterol (Eukaryotes) Same for Eukaryotes 7. Cell wall: protects against harsh changing environments and osmotic stress, contains peptidoglycan in bacteria, contains Gram + and Gram - Steps of Gram stain: dye with crystal violet, iodine (mordant), alcohol (decolorizer), and safranin red If mycobacteria complete an acid-fast stain Gram + has LTA an TA and one membrane Gram - has LPS and 2 membranes 8. Capsule: protective protein shell, outermost layer 9. Pilus: medium projection, adheres to surfaces, does DNA gene transfer 10. Flagellum: long protein projections made of flagellin for movement (ex: 1= monotrichous, one at each end = amphitrichous, many at one end = lophotrichous, many flagella all over the cell = peritrichous 11. Plasmid: circular, double-stranded DNA not part of the chromosome, and can have 1-100 of the same or different plasmids to help with gene transfer, antibiotic resistance, and virulence factors, found anywhere in the cytoplasm Not part of Eukaryotes 12. Inclusion: not all bacteria have, helps with the storage of nutrients and other materials, has protein shell, and is found in cytoplasm (ex: lipid droplets store fats, volutin stores inorganic phosphates, sulfur inclusions store sulfur, gas bubbles store gas for buoyancy in water, magnetosomes store metals for movement) Not part of Eukaryotes; instead, they have vesicles for storage All cellular microbes have what four (4) components? Cell Membrane, Cytoplasm, Ribosomes, and DNA What is the only component of all cells that viruses have? Cytoplasm Know/ be able to identify the shapes of bacteria Round shape: coccus Rod shape: bacillus Vibrio: curved rod shape Short rods with combo of coccus and bacillus: coccobacillus Wavy spiral shape: Spirillum Coiled spiral shape: Spirochete Microbial growth Phases of growth Lag Phase: bacteria gear up for replication by increasing cell size, metabolism, and protein synthesis Log Phase: exponential growth phase, where bacteria actively replicate and are most susceptible to antibiotics Stationary Phase: growth curve flatlines bc bacteria are dying at same rate of growth, begin survival mode and sporulation, produce secondary metabolites, and produce virulence factors, and are low on space, nutrients, and oxygen Death Phase: bacteria die at exponential rate, increase amount of toxic waste, release spores, some spontaneously lyse to feed others, and persister cells refuse to die How do microbes replicate? Through binary fission, fragmentation, budding, and sexually What is a biofilm? Communities of bacteria (steps: colonization, attachment, replication, make EPS with antibiotic resistance, EPS kick bacteria out to replicate somewhere else) How does quorum sensing work? Bacteria want to work together, so they secrete autoinducers, and when you activate enough receptors, they activate a response Growth requirements – classifications and adaptations 1. Oxygen requirements Obligate Aerobes: need O2 to survive Obligate Anaerobes: die in presence of O2 Faculative: mostly need O2 but can survive without it Microaerophiles: need O2 for survival but not atmospheric O2 (low levels) Aerotolerant: can survive with or without oxygen Capnophiles: like high CO2 and low O2 2. pH requirements Acidophiles: low pH (2-4), high H+ environments, efflux pumps to remove H+ ions, changes membrane composition to withstand low pH Neutrophiles: neutral pH (7), found within body Alkaliphiles: basic pH (9-10), modified lipid protein structures, modified electron transport system that use Na+ instead of H+, high OH- environment 3. temperature requirements Psychrophiles: like freezing temperatures a below 0-15 degrees, die at or above 20 degrees, found in cold lakes or the ocean floor, have hydrophobic proteins to increase flexibility, have decreased secondary stabilizing bonds Psychrotolerant: cold not ideal but wont kill them, live between 4-25 degrees (fridge temperature) Mesophiles: moderate temperatures, 20-40 degrees, grow in body Thermophiles: hot environments 50-80 degrees, hot springs, geothermal soil Hyperthermophiles: very hot environments 80-110 degrees, found in hydrothermal vents, increased saturation in membranes, increased stabilizing bonds, alter amino acids to prevent denaturation 4. osmolarity requirements Hypertonic: more water out Hypotonic: more water in Isotonic: equal water in and out Halotolerant: dont require salt but can grow in high salt environments Halophiles: love salt, found in ocean and salt lakes, have increased cytoplasmic glycerol, have efflux pumps for salt 5. barometric requirements Barophile: survive high atmospheric environments like the bottom of the ocean (something at top of mountain has low atmospheric pressure) Microbial Metabolism Means of generating energy (do the processes require oxygen?, which gives the most energy?) Glycolysis: does not require O2 bc it can be used during fermentation, used 2 ATP, makes 4 ATP, NET 2 ATP Kreb’s cycle: requires O2; NET after 1 round= 1ATP, 1 NADH, 1FADH2 (x2 for second round) Electron transport: requires O2, biggest payout of ATP with NET 34 ATP Photosynthesis: does not require O2 as it is a waste product, can do oxygenic and anoxygenic Microbial genetics DNA Replication – enzymes and functions DNA gyrase: unwinds DNA (enzyme) Helicase: unzips DNA (enzyme) Single-stranded binding proteins: bind to DNA so doesnt close back up (protein) Single-stranded binding proteins: bind to DNA so doesnt close back up (protein) DNA polymerase III: lay down new DNA nucleotides, synthesizes leading and lagging strands 5’ →3’(enzyme) DNA polymerase I: removes RNA primers (enzyme) DNA Ligase: seals RNA primers (enzyme) Topoisomerase 4: separates 2 circular chromosomes Transcription and translation – enzymes and function 1. RNA polymerase: turns DNA→ mRNA (transcription) 2. Ribosomes: 30S small, 50S large, 70S total 3. tRNA: A,P, and E sites, bacteria links transcription and translation bc no nucleus, has anticodon at opposite long 3’ end, high energy bond, same active translation process as Eukaryotes Be able to do DNA base pairing, transcription, and translation (given codon table) Also know differences between prokaryotic and eukaryotic Replication, transcription, and translation Genetic Diversity – how does this work? 1. Transformation: uptake of plasmid into different bacteria and is incorporated into its genetic material 2. Transduction: bacteriophage inserts its plasmid into a bacteria (virus that infects a bacteria) 3. Conjugation: like plasmid transfer (ex: rolling circle replication), “bacterial sex” 4

Lipid droplets

Learning Rate and Overfitting/dropout

Week 5 Absolutely — here’s a condensed study guide that keeps the major concepts (the stuff most likely to be tested), without all the extra detail. Infection Control & Body Defenses — Condensed Study Guide (Major Concepts) Chain of Infection (6 Links + how to break them) 1. Infectious agent (bacteria, viruses, fungi, parasites, prions) ○ Break it: disinfect/sterilize/clean; antimicrobials as ordered 2. Reservoir (where it lives: people/animals/insects; soil, water, food, equipment, IV fluids, feces) ○ Break it: hand hygiene, pre-op skin prep, environmental cleaning 3. Portal of exit (blood/body fluids, respiratory/GI tract, mouth/nose/ears, skin) ○ Break it: contain drainage/secretions (dressings, drains) 4. Mode of transmission ○ Main: contact, droplet, airborne (also vehicle, vector) ○ Break it: hand hygiene + PPE + disinfect shared equipment 5. Portal of entry (orifices, mucous membranes, breaks in skin; invasive devices) ○ Break it: aseptic technique, protect skin, sterile technique when needed 6. Susceptible host (risk depends on immunity/health) ○ Break it: immunizations, nutrition, hygiene, blood sugar control Virulence: how efficient an organism is at making people ill. Modes of Transmission (what to recognize) Contact ● Direct: person-to-person (ex: blood to open abrasion) ● Indirect: contaminated objects/PPE/equipment (ex: bed rails, shared devices) Droplet ● From coughing/sneezing/singing/talking; some procedures (CPR, intubation) ● Examples: influenza, pertussis, RSV, adenovirus, rhinovirus ● Respiratory etiquette + masking when out of room Airborne ● Small particles remain suspended; travel farther ● Requires private room; negative pressure (AIIR) preferred ● Examples: TB, measles (rubeola), varicella Vehicle / Vector ● Vehicle: contaminated food/water (ex: E. coli produce) ● Vector: insects/rodents (mosquitoes, rats) Body Defenses (3 Types) 1. Physical & chemical barriers ○ Skin (primary defense), mucous membranes/mucus, tears/sweat, cilia + cough, stomach acid, normal flora 2. Nonspecific immunity ○ Neutrophils + macrophages (phagocytes “eat and destroy”) 3. Specific immunity ○ Antibodies (immunoglobulins) + lymphocytes Inflammatory Response (key steps + signs) Steps: ● Pattern receptors recognize harmful stimuli ● Inflammatory pathway activated ● Markers released (ex: CRP) ● Inflammatory cells recruited (leukocytes → monocytes/lymphocytes) Signs of inflammation (local tissue): ● heat, redness, swelling, pain, loss of function Triggers can be infectious (viruses/bacteria) or noninfectious (trauma, burns, irritants, toxins, radiation, etc.). Stages of Infection (in order) 1. Incubation (exposure → first symptom; may have lab changes) 2. Prodromal (vague symptoms: malaise, fever, aches) 3. Acute illness (most severe; specific symptoms) 4. Decline (symptoms decrease) 5. Convalescence (recover/return to baseline) Local vs Systemic Infection ● Local: confined to one area (often topical/oral treatment) ● Systemic: enters bloodstream, affects whole body (often IV antibiotics + monitoring) Diagnostic Tests (high-yield) ● UA for UTI symptoms → if WBCs present, culture & sensitivity ● CXR confirms pneumonia/atelectasis but doesn’t tell viral vs bacterial ● CBC + differential ○ Expected WBC: 5,000–10,000/mm³ ○ “Left shift” = increased bands (immature neutrophils) → infection ● Nonspecific markers: CRP, ESR, Procalcitonin Asepsis & Precautions Hand hygiene (most important) ● Soap/water when visibly soiled and for C. diff spores ● Alcohol sanitizer works unless hands visibly soiled Medical asepsis (clean technique) ● reduces microbes; includes isolation precautions Surgical asepsis (sterile technique) ● prevents introducing microbes during invasive procedures; uses sterile supplies/fields Isolation Precautions (major takeaways) Standard precautions ● For all clients ● Protect from blood/body fluids, secretions, excretions, nonintact skin, mucous membranes ● PPE based on expected exposure Contact precautions ● Gown + gloves ● Examples: C. diff, VRE, norovirus, RSV, large draining wounds ● Remove PPE inside room Droplet precautions ● Surgical mask ● Examples: influenza, pertussis, RSV Airborne precautions ● N95 or higher, private room; AIIR/negative pressure preferred ● Examples: TB, measles, varicella Protective isolation (protective environment) ● For severely immunocompromised (ex: post-allogenic HSCT) ● Positive airflow + HEPA (goal: protect the client) Health Care–Associated Infections (HAIs) — the “big 4” ● CLABSI ● CAUTI ● SSI ● VAP Devices/lines/wounds create portals of entry → strict asepsis reduces risk. MDROs (major concept) MDROs = resistant bacteria (hard to treat) Examples: MRSA, VRE, VRSA, VISA, ESBL, MDRSP Prevention: hand hygiene, contact precautions per policy. If you want, I can turn this condensed guide into a 20-question practice quiz (ATI/NCLEX-style) focusing on chain links, precautions, PPE, labs, and transmission. Week 6 Here is a more condensed study guide that keeps all main concepts from your content (no major topics removed), just simplified and streamlined for studying. Condensed Study Guide: Novice to Expert + Nursing Communication I. Novice to Expert Nursing (Benner Model) Lifelong Learning & Collaboration ● Learning occurs through study and working with others ● Nurses grow by: ○ observing experienced nurses ○ sharing knowledge and best practices ● Respect all experience levels (years ≠ only indicator of knowledge) ● Leaders promote: ○ collaboration ○ mutual respect ○ teamwork culture Benner’s 5 Stages of Competence 1. Novice – no experience; relies on rules; struggles to prioritize 2. Advanced Beginner – recognizes patterns; still rule-focused; needs help setting priorities 3. Competent – uses past experience to prioritize; more organized but slower than proficient 4. Proficient – sees the big picture; adapts to changing situations 5. Expert – intuitive, confident, and highly skilled with complex care II. Communication Foundations Definition Communication = transfer of information that is always occurring, even without speaking. Includes: verbal words, body language, emotions, and technology. Why Communication Matters ● Key to client safety (Joint Commission goal) ● Miscommunication → medical errors ● Nurses must detect when clients don’t understand III. Communication Models (Core Concepts) Shannon–Weaver Model (Linear) Sender → Encoder → Channel → Decoder → Receiver + Noise (distractions interfering with message) Schramm Model (Feedback) ● Sender and receiver exchange messages ● Feedback confirms understanding ● No feedback = communication incomplete Newcomb ABX Model (Social) ● A (sender), B (receiver), X (topic affecting interaction) ● Focus on relationships and shared topic Berlo S-M-C-R Model (One-way) ● Sender → Message → Channel → Receiver ● No feedback loop IV. Forms of Communication Verbal Spoken communication (face-to-face or phone) Nonverbal (Body Language) ● Eye contact, posture, facial expressions ● When verbal and nonverbal conflict → nonverbal dominates Auditory What the receiver hears (tone, speed, clarity) Emotional Speaker’s emotional state influences how message is received Energetic Speaker’s presence/empathy affects perception of message V. Modes of Communication (4 Types) 1. Verbal – spoken conversation 2. Nonverbal – gestures, posture, appearance 3. Electronic – email, text, video (must be secure/HIPAA compliant) 4. Written – letters, emails, documents (may lack tone/body language) HIPAA & Electronic Communication Must include: ● secure messaging ● unique logins ● auto logoff ● encrypted/indecipherable PHI VI. Communication Styles Most effective: Assertive ● Passive: avoids conflict; agrees despite concerns ● Assertive: clear, respectful, confident; uses “I” statements ● Aggressive: blaming, hostile, controlling ● Passive-aggressive: indirect expression (sarcasm, avoidance) VII. Therapeutic Communication Purpose Build trust and provide patient-centered, empathetic care Cornerstones ● Compassion ● Caring ● Empathy Peplau’s Nurse-Client Relationship Phases 1. Orientation – client seeks help 2. Identification – relationship forms 3. Exploitation – active teaching/working phase 4. Resolution – issue resolved; relationship ends Watson’s Theory of Human Caring ● Authentic presence ● Protect dignity ● Loving-kindness ● “Healing moment” interactions VIII. Therapeutic Communication Techniques (Must Know) ● Active listening – attend to verbal + nonverbal cues ● Open-ended questions – encourage discussion (“Tell me more…”) ● Silence – allows client to reflect and share more ● Restating / summarizing – repeat message to confirm understanding ● Reflection – mirror feelings (“What do you think you should do?”) ● Accepting – acknowledge message without judgment ● Giving recognition – note change without compliment ● Focusing – gently redirect to important topic ● Offering self – sit with client and be present IX. Nontherapeutic Communication (Avoid) ● Giving advice ● False reassurance (“You’ll be fine”) ● Criticizing or challenging ● Asking “Why” questions ● Rejecting or disagreeing ● Probing irrelevant topics ● Changing the subject Effects: ● increased stress ● damaged trust ● poor outcomes X. Interprofessional Communication Importance Effective teamwork improves: ● client outcomes ● safety ● efficiency ● reduces errors IPEC Core Competencies 1. Mutual respect among team members 2. Use shared knowledge collaboratively 3. Communicate effectively as a team 4. Support team values and client-centered care XI. Motivational Interviewing (MI) Purpose Encourage behavior change (diabetes, obesity, substance use) OARS Technique ● Open-ended questions ● Affirmations (positive encouragement) ● Reflective listening ● Summarizing XII. Group vs Individual Communication ● Individual: new diagnosis, personal teaching ● Group: ongoing education, support groups XIII. Communication Barriers (Major Categories) Cognitive/Developmental ● dementia, stroke, autism Physiological ● hearing loss, vision impairment Cultural & Language ● language differences, cultural beliefs, lack of cultural competence Environmental/Situational ● noise, lighting, temperature ● fear, anxiety, fatigue, stress Technological ● poor reception, distractions, electronic errors XIV. Strategies to Overcome Barriers Universal Strategies ● show empathy and respect ● avoid interrupting ● use simple, clear language ● confirm understanding (summarize/reflect) Language Barriers (CLAS Standards) ● Use qualified medical interpreter ● Do NOT use family members or translation apps ● Required for federally funded facilities Hearing Impairment Strategies ● face the client ● speak clearly/moderate pace ● reduce background noise ● use written info or visual aids ● ensure hearing aids in place ● speak to client (not interpreter) if interpreter present Vision Impairment Strategies ● introduce yourself ● give clear directions (“door at 10 o’clock”) ● allow client to hold your arm ● provide large print/audio/Braille materials Cognitive/Developmental Strategies ● use simple words ● avoid jargon/slang ● speak slowly and clearly ● reduce noise/bright distractions ● ensure glasses/hearing aids available Key Takeaways (Exam Focus) ● Benner’s stages: Novice → Advanced Beginner → Competent → Proficient → Expert ● Communication must include feedback to be effective ● Nonverbal cues often outweigh verbal messages ● Best communication style = Assertive ● Core therapeutic techniques = active listening, open-ended questions, silence, reflection, summarizing ● Use qualified interpreter for language barriers (CLAS standard) ● Barriers include cognitive, physical, cultural, environmental, and emotional factors ● Effective communication improves client safety and outcomes Here is a condensed but complete study guide that keeps all concepts from the Safety lesson while removing extra wording. SAFETY & PATIENT PROTECTION – CONDENSED STUDY GUIDE I. Joint Commission National Patient Safety Goals (NPSGs) Purpose Annual goals to improve: ● Client safety ● Safe, effective care ● Prevention of adverse outcomes 1. Identify Clients Correctly ● Use two identifiers (name, DOB, MRN, etc.) ● Confirm before meds, procedures, treatments ● Ask open-ended questions ● Verify ID band & EMR ● Use barcode scanning ● ❌ Never use room number 2. Improve Staff Communication ● Report critical results immediately ● Critical results = life-threatening abnormal labs/diagnostics ● Facility policies define: ○ critical result criteria ○ reporting timeframe ○ documentation requirements ● Communicate directly (in person/phone), not voicemail (HIPAA) 3. Use Medications Safely Label medications ● Label all syringes/containers with name, dose, date/time ● Discard unlabeled meds Anticoagulant safety ● Examples: warfarin, heparin, enoxaparin ● Monitor labs, weight, interactions, dosing ● Educate on risks, food interactions, follow-up labs Medication reconciliation ● Compare home meds with new prescriptions ● Done on admission, transfer, discharge ● Resolve discrepancies 4. Use Alarms Safely ● Clinical alarms warn of patient events or equipment malfunction ● Examples: IV pumps, ventilators, monitors, bed/chair alarms ● Risk: alarm fatigue ● Nurse role: ○ know alarm priorities ○ respond promptly ○ help develop alarm policies 5. Prevent Hospital-Acquired Infections (HAIs) Common HAIs: ● CLABSI ● CAUTI ● SSI ● VAP Concern: MDROs (MRSA, VRE, C. diff) ⭐ Hand hygiene = most important prevention Compliance required with monitoring and action plans. 6. Identify Safety Risks: Suicide Prevention ● Screen behavioral health clients ≥12 yrs ● Positive screen → detailed suicide assessment ● Implement: ○ constant observation ○ removal of harmful items ○ environmental safety checks ○ staff competency training 7. Universal Protocol (Surgery Safety) Prevent wrong-site/procedure/client: 1. Two identifiers 2. Mark surgical site (if applicable) 3. Time-out before procedure 4. Verify consent & procedure with client 8. Improve Health Care Equity (2024 Goal) Assess social determinants: ● literacy ● housing ● transportation ● food access Continue assessment throughout hospitalization and discharge planning. II. Standards of Compliance Former NPSGs now routine standards: ● Medical error prevention ● Staff competency verification ● Client rights & education ● Infection control ● Medication management ● Emergency preparedness III. Culture of Safety Promotes: ● open communication ● reporting of errors & near misses ● nonpunitive environment ● improved outcomes & staff satisfaction Nurses play key role due to frequent client contact. IV. Transforming Care at the Bedside Initiative 1. Spend 70% of time in direct bedside care 2. Leadership development 3. Rapid Response Team (RRT) 4. Standardized communication (ISBARR) Benefits: ● fewer falls, HAIs, med errors ● improved outcomes and satisfaction V. Rapid Response Team (RRT) Interdisciplinary team (ICU nurse, RT, provider) for sudden deterioration. Call RRT for: ● sudden vital sign changes ● low O₂ despite intervention ● chest pain after nitro ● seizure ● sudden mental status change ● serious clinical concern VI. ISBARR Communication Tool 1. Identity 2. Situation 3. Background 4. Assessment 5. Recommendation 6. Read-back VII. Types of Unexpected Events ● Near miss: error caught before harm ● Client safety event: event with potential harm ● Adverse event: unexpected harm occurred ● Sentinel event: severe harm/death (never event) Examples sentinel: ● wrong-site surgery ● suicide in facility ● serious fall injury VIII. Occurrence (Incident) Reporting Purpose: improve systems, prevent future errors (not punishment) Report: ● falls/injuries ● wrong meds ● adverse reactions ● blood/body fluid exposure ● property damage ● unsafe behaviors/events IX. Safety Assessment & Agencies Regulated by: ● TJC ● CMS ● OSHA ● State boards & local agencies Nursing safety focus: ● falls ● meds & allergies ● restraints ● pressure injury prevention ● infection control ● sharps & pathogen exposure ● body mechanics ● fire, chemical, radiation safety X. Electrical Safety Check: ● frayed cords ● grounded 3-prong plugs ● GFCI outlets ● no wet handling ● avoid extension cords ● tag/remove faulty equipment XI. Chemical Safety Exposure routes: ● inhalation ● skin/eyes ● ingestion ● injection (needlestick) Use: ● SDS sheets ● PPE (gloves, masks, gowns, goggles) ● ventilation systems ● emergency eye wash/showers XII. Radiation Safety Risk proportional to: ● exposure time ● distance from source Principles: 1. Reduce time 2. Increase distance 3. Shield (lead aprons, barriers) Types: ● Alpha (least risk, short travel) ● Beta (moderate risk, small distance) ● Gamma (highest risk, penetrates tissue) Initial symptoms: ● nausea, vomiting, diarrhea ● burns, alopecia ● immunocompromise ● psychological effects XIII. Age-Related Safety Risks Infants/Preschoolers ● burns, poisonings, choking, drowning ● car seat safety ● smoke detectors & safe storage of toxins School-Age ● sports injuries, firearm safety, internet risks Adolescents ● substance use, risky driving, violence, suicide risk Adults/Older Adults ● chronic illness, frailty, mobility decline ● ⭐ Major risk: falls ● frailty → poorer outcomes XIV. Hospital-Acquired Injuries Include: ● SSIs, CAUTIs, CLABSIs ● falls, trauma ● pressure injuries ● DVT ● insulin errors ● transfusion reactions ● burns/electrical shock High-risk clients: ● neurologic disorders (stroke, MS, Parkinson’s) ● cognitive impairment, dementia ● communication disabilities ● visual deficits ● behavioral disorders XV. Screening Tools Used to identify early risk: ● Morse Fall Scale (fall risk) ● Braden Scale (pressure injury risk) ● Tools must be valid/reliable Positive results → detailed assessment + individualized care plan. XVI. Home Hazard Safety Bathroom: ● grab bars, non-slip mats, raised toilet, step-free showers Bedroom: ● low bed, alarms, hospital bed if needed Kitchen: ● reachable items, automatic stove shut-off, secure chemicals General: ● good lighting, remove loose rugs, secure cords, install handrails ● cordless blinds for child safety ● emergency numbers accessible XVII. Fire Safety RACE ● Rescue ● Alarm ● Contain (close doors/windows) ● Extinguish PASS ● Pull pin ● Aim at base ● Squeeze ● Sweep Fire extinguisher types: ● A: paper/wood ● B: liquids/oils ● C: electrical ● D: metals ● K: kitchen grease ● ABC: multipurpose Evacuation: ● Lateral = same floor (preferred) ● Vertical = different floor XVIII. Workplace Safety Bullying ● Repeated harassment/belittlement ● Leads to burnout, errors, poor retention Workplace Violence Includes verbal abuse to homicide Risk factors: ● violent clients ● staff shortages ● long wait times ● lack of training/security Active Shooter Response 1. Run 2. Hide 3. Fight (last resort) XIX. Emergency Preparedness Facilities must have: ● disaster plans ● staff training & drills ● defined staff roles Types of mass exposure: ● Radiation ● Biological (anthrax, Ebola, COVID) ● Chemical toxins Response: ● PPE ● decontamination (remove clothing, shower) ● monitor vitals & mental status XX. Injury Prevention Strategies ● hourly rounding ● video monitoring ● bedside sitters ● individualized safety plans ● prompt call-light response XXI. Fall Prevention Risk factors: ● weakness, gait issues, vision problems ● confusion, dementia, impulsiveness ● clutter, poor lighting ● high-risk meds (antihypertensives, antidepressants) ● incontinence, age Universal precautions: ● nonskid footwear ● low bed & locked wheels ● clutter-free room ● call light within reach ● hourly rounding & quick response Movement alarms = warning device Siderails: ● 2 rails for safety ● 4 rails = restraint (intent matters) XXII. Restraints & Seclusion Types: ● Physical: manual holding ● Mechanical: mitts, wrist, vest, 4-point ● Chemical: sedatives/antipsychotics ● Barrier: enclosures, lapboards, 4 rails ● Seclusion: locked room Use ONLY as last resort when: ● danger to self/others ● removing life-saving devices ● severe aggression Care of restrained client: ● frequent circulation, skin, respiratory checks ● ROM, hygiene, fluids, elimination ● reevaluate every 24 hrs ● discontinue ASAP XXIII. Seizure Precautions Preseizure ● suction & oxygen ready ● padded rails ● IV access ● remove restrictive clothing/jewelry During seizure ● call for help ● side-lying position ● protect head ● do NOT restrain ● monitor duration & movements ● give benzodiazepine if ordered Postseizure ● assess gag reflex before oral intake ● reassure client ● labs, EEG, imaging as ordered XXIV. Musculoskeletal Injury Prevention (Nurse Safety) Use assistive devices: ● Hoyer lift (ground lift) ● ceiling lift ● slide sheets ● sit-to-stand lift Safe handling: ● clear area ● use correct sling size ● have 2 staff assist ● lock brakes ● never leave client unattended XXV. Patient-Centered Care Focus: ● client as center of care ● collaboration & shared decision-making ● respect cultural, spiritual, religious needs ● holistic & individualized care ● include pastoral care support FINAL MEMORY CHECK (High-Yield Core Concepts) ● Two identifiers before any care ● Hand hygiene prevents HAIs ● Time-out before surgery ● ISBARR improves communication ● RRT for sudden deterioration ● Fall prevention + restraints last resort ● RACE & PASS fire response ● Run–Hide–Fight for active shooter ● Time–distance–shielding for radiation safety ● Screening tools identify early risks Here is a fully condensed study guide that includes ALL major topics and concepts from your lesson (patient-centered care, caring theories, cultural care, spirituality, advocacy, sleep & rest) without leaving anything out. CONDENSED STUDY GUIDE: PATIENT-CENTERED CARE, CARING, CULTURE, ADVOCACY & SLEEP I. Patient-Centered Care Definition Patient-centered care = placing the client at the center of all care, focusing on preferences, culture, and holistic needs rather than just tasks or documentation. Key Concepts ● Improves client satisfaction and outcomes ● Involves caring, preferences, cultural respect, and shared decision-making ● Holistic care: physical, emotional, spiritual needs II. Caring in Nursing Definition Caring = nurturing another person with responsibility and commitment; core of professionalism. Holistic Caring Includes ● Healing environment ● Kindness, empathy, compassion ● Addressing physical, emotional, and spiritual needs III. Caring Theories A. Watson’s Theory of Human Caring Holistic model focusing on mind-body-spirit harmony through transpersonal (human-to-human) caring relationships. Core Ideas ● Caring moments foster healing and self-restoration ● Nurse must achieve inner balance and spirituality ● Establish trusting presence and relationships 10 Caritas Processes 1. Loving-kindness and compassion 2. Authentic presence and honoring beliefs 3. Sensitivity to self and others 4. Trusting caring relationships 5. Expression of feelings 6. Creative problem-solving through caring 7. Transpersonal teaching/learning 8. Healing environment (comfort, dignity, peace) 9. Reverent assistance with basic needs 10. Openness to spirituality and miracles B. Swanson’s Theory of Caring Caring improves well-being through empowerment, dignity, and respect. Five Caring Processes 1. Maintaining belief – instill hope and meaning 2. Knowing – understand client’s situation/perception 3. Being with – emotional and physical presence 4. Doing for – perform needed tasks for client 5. Enabling – guide and support through events/transitions IV. Caring Behaviors 1. Listening ● Active, empathetic listening ● Observe verbal and nonverbal cues ● Key for holistic assessment and trust 2. Touch ● Used for procedures and expressive caring ● Requires permission; consider culture, trauma, gender ● Can reduce anxiety and increase well-being 3. Being Present ● Physical and emotional availability ● Reduces loneliness and improves comfort ● Reflects “being with” (Swanson) 4. Providing Comfort ● Pharmacologic and nonpharmacologic comfort measures ● Examples: pillows, blankets, hygiene, music, temperature control ● Represents “doing for” 5. Showing Compassion ● Recognize suffering and act to relieve it ● View client as person, not diagnosis ● Requires self-awareness and adequate staffing V. Client Preferences in Care Clients are full members of the health care team and experts on their own experiences. Benefits ● Increased trust and satisfaction ● Improved healing and outcomes ● Greater sense of control Ways to Include Preferences 1. Endorsing participation – empower involvement 2. Promoting understanding – correct misinformation 3. Sharing information – two-way communication Barriers ● Power imbalance ● Medical jargon ● Weakness, fatigue, cognitive impairment ● Poor collaboration and language barriers VI. Cultural Competence Definition Evidence-based care aligned with client’s cultural values, beliefs, and practices. Influencing Factors ● Socioeconomic status ● Health literacy ● Racism experiences ● Sexual orientation ● Acculturation (adapting to another culture) Five Elements of Cultural Competence 1. Cultural awareness – self-examine biases 2. Cultural knowledge – learn client values/beliefs 3. Cultural skill – assess cultural needs accurately 4. Cultural encounters – interact with diverse cultures 5. Cultural desire – motivation to connect with cultures Cultural Assessment Includes ● Cultural/spiritual affiliation ● Health beliefs and practices ● Spiritual rituals ● Dietary preferences/prohibitions ● Care preferences to increase comfort VII. Age-Related (Generational) Care Preferences Generation Preferences Silent (1928–1945) Formal, face-to-face, written communication Baby Boomers Team-oriented, sincere, in-person communication Gen X Direct, independent, questions providers Millennials Tech-based communication, frequent feedback Gen Z Digital natives, prefer texting/email Gen Alpha Tech-savvy children; family-centered care VIII. Spiritual Nursing Care Spiritual Well-Being Feeling of meaning, purpose, and connection to higher power → improves quality of life. Spiritual Assessment Questions ● Source of spiritual strength? ● Meaning-of-life concerns? ● Relationship with higher power? ● Spiritual practices? ● Fear of dying? ● Relationship concerns? Assessment Tools FICA: ● Faith ● Importance ● Community ● Address in care HOPE: ● Hope sources ● Organized religion ● Personal spirituality/practices ● Effects on care/end-of-life issues IX. Spiritual Distress Definition Questioning life meaning or beliefs causing despair, anger, fear, uncertainty. Nursing Interventions ● Listen and be present ● Encourage spiritual expression ● Provide prayer, texts, pastoral referral ● Address emotional and spiritual needs X. Pastoral Care Provides: ● Ethical, religious, and spiritual support ● Counseling, prayer, rituals ● End-of-life and grief support ● Support for families and staff Chaplains assist all clients regardless of religion. XI. Access to Care Barriers ● Lack of insurance ● Transportation problems ● Limited providers/facilities (rural areas) ● Restricted clinic hours ● Medication cost barriers Solutions ● Telemedicine: remote diagnosis/testing ● Telehealth: broader remote clinical and nonclinical services ● Improves access, especially rural areas XII. Client Advocacy Definition Protect client autonomy, rights, and safety; act as client’s voice. Clients Needing Advocacy ● Unconscious ● Children ● Fearful/intimidated clients ● Uninformed about diagnosis/rights Advocacy Steps 1. Assess needs, values, cognition, resources 2. Verify client goals/preferences 3. Implement plan and communicate with team 4. Evaluate outcomes and self-determination Related Concepts ● Medically futile: treatment unlikely to cure or extend life ● Potentially inappropriate treatment: works but may not improve quality of life ● Palliative care: symptom relief + quality of life ● Quality of life: personal meaning, independence, relationships XIII. Sleep and Rest Importance of Sleep Supports: ● Memory, learning, concentration ● Immune system and tissue repair ● Hormone balance (ghrelin, leptin, cortisol) ● Mood, reaction time, coordination ● Prevention of obesity, diabetes, cardiovascular disease XIV. Physiology of Sleep Key Brain Structures ● Cerebral cortex: sensory processing & memory ● Brainstem: controls REM and muscle relaxation ● Hypothalamus: autonomic control, circadian rhythm (SCN) ● Thalamus: sensory filtering during sleep ● Pineal gland: produces melatonin XV. Sleep Regulation Mechanisms 1. Circadian rhythm – 24-hour internal sleep–wake cycle influenced by light and temperature 2. Sleep–wake homeostasis – pressure to sleep increases with sleep deprivation Factors affecting sleep: ● Light exposure ● Stress ● Medications ● Caffeine/food ● Environment XVI. Stages of Sleep NREM Sleep Stage 1: Light sleep; easily awakened (5%) Stage 2: Deeper sleep; decreased HR/temp; memory consolidation (50%) Stage 3: Deep sleep; delta waves; immune strengthening and tissue repair (15%) REM Sleep ● Dream stage ● Irregular breathing and increased HR ● Muscle atonia (prevents acting out dreams) ● Occurs ~90 minutes after sleep onset Sleep cycles repeat 4–6 times per night. XVII. Sleep Patterns by Age ● Newborns: multiple cycles, high REM ● Adults: 2–5% stage 1, 45–55% stage 2, 10–20% stage 3, 20–25% REM ● Older adults: less deep sleep, more awakenings XVIII. Sleep Deprivation Types ● Total: no sleep for extended period ● Partial: reduced sleep hours ● Chronic: ongoing insufficient sleep ● Selective: loss of specific sleep stage Effects ● Impaired judgment and memory ● Mood swings, depression ● Increased accidents and chronic illness risk ● Poor glucose control and obesity XIX. Promoting Sleep Nonpharmacologic Interventions ● Avoid caffeine, nicotine, alcohol before bed ● Keep room dark, quiet, cool ● Establish bedtime routine ● Consistent sleep schedule ● Exercise regularly (not right before bed) ● Limit naps (<30 minutes) ● Remove electronics/TV from bedroom XX. Sensory Overload in Hospital Definition: Excess stimuli beyond brain’s processing ability → sleep disruption. Nursing Interventions ● Lower noise and alarms ● Dim lights ● Provide earplugs/eye masks ● Cluster care tasks ● Control pain and medication effects XXI. Sleep Disorders Insomnia Difficulty falling/staying asleep → fatigue, poor concentration, mood changes Sleep Apnea ● Central: brain fails to signal breathing ● Obstructive: airway collapse; snoring; daytime sleepiness Treatment: CPAP, weight loss, avoid alcohol/smoking Narcolepsy Sudden sleep attacks; possible cataplexy (loss of muscle tone) Hypersomnia Excessive daytime sleepiness despite adequate sleep Restless Legs Syndrome (RLS) Urge to move legs; worsens at night; disrupts sleep Night Terrors Non-REM parasomnia causing panic and no recall; common in children XXII. Pharmacologic Sleep Therapies ● Benzodiazepines (GABA agonists): sedative but dependency risk ● Nonbenzodiazepine hypnotics (most common) ● Melatonin: low-risk first-line option ● Antihistamines: OTC but cause side effects XXIII. Nonpharmacologic Sleep Therapies ● Massage, acupuncture, thermotherapy ● Guided imagery, meditation, music therapy ● Yoga and relaxation techniques ● Sleep diaries to identify patterns and personalize care FINAL KEY POINT Patient-centered nursing integrates: ● Caring theories ● Cultural competence ● Spiritual support ● Client advocacy ● Sleep and comfort promotion Goal: provide holistic care that supports physical healing, emotional well-being, spiritual meaning, autonomy, and optimal quality of life. Week 7 Absolutely—here’s a more condensed study guide that still includes every concept you were given. CONDENSED STUDY GUIDE: ELIMINATION (ALL CONCEPTS) 1) Big Picture ● Elimination (urine + stool) is continuous and essential. Patterns vary, but changes require assessment + intervention to restore usual patterns or establish a new baseline. 2) Urinary System Basics Functions: excrete waste/fluid → urine, regulate electrolytes, support RBC production, help regulate BP, support bone health. Pathway: kidneys → ureters → bladder → urethra → urination. Control: internal sphincter + external sphincter + pelvic floor muscles prevent leakage. Urination: elimination of urine via urethra. 3) Urine Production & Assessment Normal: clear, light yellow, minimal odor. Typical daily amount: ~1–2 quarts/day (varies). Expected output by age: infant ~2 mL/kg/hr; toddler ~1.5; teen ~1; adult ~0.5. Color clues: ● Dark yellow/amber = need fluids ● Dark brown = dehydration/kidney/liver concern ● Red/pink = blood or foods (beets, blackberries, rhubarb) Diet/med effects: ● Fluids ↑ volume, lighter color ● Asparagus ↑ odor ● Dyes can turn blue/green ● Alcohol + caffeine ↑ urine output (can dehydrate if not balanced) Aging urinary changes: ↓ nephrons/kidney function, ↓ bladder tone → incontinence/retention risks. 4) GI System Basics Organs: mouth → esophagus → stomach → small intestine → large intestine → rectum → anus. Peristalsis: contractions that move contents through GI tract. Feces formation: digestion + absorption (small intestine), water absorption + stool formation (large intestine), bacteria help + make vitamin K, rectum stores stool until BM. Bristol Stool Chart: ● Types 1–2 = constipation ● Types 3–4 = expected ● Types 5–7 = diarrhea Aging GI changes: ↓ peristalsis/muscle tone → constipation; ↑ PUD risk (NSAIDs), ↓ elasticity/emptying changes, possible ↓ absorption/bacterial overgrowth, ↓ lactase → lactose intolerance; lifestyle factors (inactivity, low fiber/fluids, meds) contribute. 5) Expected Elimination ● Urine: clear, light yellow, varies with intake/activity/diuretics. ● Stool: frequency varies widely; should be soft/formed, easy to pass without straining. 6) Altered Urinary Elimination Urinary Incontinence (UI) Involuntary urine loss. Can cause skin breakdown + distress. Types: ● Stress: cough/sneeze/exertion ● Urge: sudden urge, leak before toilet ● Reflex: nerve damage, no warning ● Overflow: incomplete emptying → overfill/leak ● Functional: can’t reach toilet (mobility/dexterity issues) ● Nocturnal enuresis: nighttime (kids; adults w alcohol/caffeine/meds) Management: lifestyle changes (↓ caffeine/alcohol, smoking cessation, address constipation), pelvic floor exercises, bladder training, meds/devices/surgery; skin protection (pads/briefs, cleanser, barrier cream). Urinary Retention Incomplete bladder emptying (acute or chronic). Causes: BPH, cystocele/prolapse, obstruction (stones/lesions). Findings: hesitancy, weak stream, frequency, distention, pain, leakage. Risks: UTI, bladder/kidney damage. 7) Altered Bowel Elimination Constipation <3 BMs/week + hard/lumpy stools, difficult to pass. Risks: pregnancy/postpartum, older adults, low fiber/fluids, meds, GI disorders, immobility. Red flags: fever, GI bleeding, severe pain, vomiting, weight loss. Complication: fecal impaction/obstruction (liquid stool may leak around impaction). Tx: fiber + fluids + exercise + bowel training; meds; enema/manual removal; surgery if complete obstruction. Diarrhea Frequent loose/watery stools: acute (1–2d), persistent (>2w <4w), chronic (>4w). Risks: infection, meds, GI disorders, diet. Dangers: dehydration, malabsorption. Adult urgent follow-up: fever ≥102°F, >2 days, ≥6/day, severe pain, blood/black stool. Tx: rehydration; OTC (loperamide/bismuth) if appropriate; antibiotics/probiotics if infectious cause. Bowel Incontinence Urge (can’t reach toilet) most common; passive (unaware leakage). Leads to skin issues + reduced self-esteem. Children: encopresis. 8) Medications That Affect Elimination Constipation: antacids (Al/Ca), anticholinergics/antispasmodics, antiseizure meds, Ca-channel blockers, diuretics, iron, antiparkinsonian, opiates, antidepressants. Diarrhea: antibiotics, magnesium antacids; consider C. diff if severe/persistent after antibiotics. 9) Conditions Altering Urinary Patterns ● Dehydration: thirst, dry mouth, fatigue, dizziness, dark urine; severe needs IV fluids. ● UTI: dysuria, urgency/frequency; can progress to pyelonephritis (fever, flank pain, N/V, hematuria). Tx antibiotics + fluids. Higher risk: females, retention, obstruction, catheters, diabetes, menopause. ● Kidney stones: severe flank pain radiating to groin, hematuria, dysuria, fever/chills, N/V. Tx fluids, pain meds, strain urine, ESWL/surgery. ● Kidney failure: waste/fluid buildup → ↓ urine, HTN, anemia, itching; Tx dialysis or transplant. ● BPH: urethral constriction → retention, nocturia, weak stream; can cause UTIs/damage; Tx meds/surgery. 10) Conditions Altering Bowel Patterns ● Diverticulosis: pouches; Diverticulitis: inflamed/infected pouch → pain/bleeding; risk perforation → peritonitis. Prevent: fiber; nuts/seeds no longer restricted. Tx antibiotics + liquid/soft diet. ● IBS: pain + diarrhea/constipation (IBS-C, IBS-D, IBS-M); Tx diet (fiber/probiotics, avoid triggers), stress reduction, sleep/exercise, meds. ● Bowel obstruction: blockage → N/V, distention, severe constipation; NG decompression + surgical consult. ● Ileus: decreased/absent motility (often post-op/illness/meds) → absent bowel sounds, distention, N/V; Tx NPO, NG tube, IV fluids; consider TPN if prolonged. ● Ulcerative colitis: colon inflammation/ulcers → bloody diarrhea, fatigue, anemia; Tx meds; surgery if refractory/cancer risk. ● Crohn’s: inflammation anywhere (often small intestine) → diarrhea, weight loss, anemia; complications fistulas/abscess/obstruction; Tx meds + possible surgery. 11) Diversions & Ostomies Urinary Diversions ● Catheterization (temporary) ● Ureteral stent ● Ileal conduit/urostomy (stoma + pouch) ● Nephrostomy (kidney → external bag) ● Neobladder (internal reservoir, may need catheter) ● Continent cutaneous reservoir (internal pouch + valve; catheter to empty) ● Cystostomy (catheter directly into bladder) Complications: UTIs, kidney infection, skin breakdown; psychosocial concerns. Fecal Diversions ● Ileostomy ● Colostomy (+ irrigation option for some permanent colostomies) ● J-pouch (internal ileal reservoir connected to anus; often temporary ileostomy first) ● Kock pouch (continent ileostomy; catheter to empty) Complications: skin irritation, hernia/prolapse/stenosis, blockage, diarrhea, bleeding, electrolyte imbalance, infection, leakage. WOC nurse supports education + supplies + skin/stoma care. 12) Diagnostics & Specimen Collection Urinary ● Urodynamics: uroflowmetry, postvoid residual, cystometric test, leak point pressure, EMG, video urodynamics, pressure-flow study ● Scopes: cystoscopy, ureteroscopy ● Urinalysis: visual + dipstick + microscopic (WBC, RBC, bacteria, casts, crystals) ● Urine culture: clean catch midstream; grows organism + susceptibility testing (correct antibiotic; reduces resistance) ● 24-hour urine: collect all urine, refrigerate, avoid certain foods/meds Urine collection methods: clean catch vs catheter (sterile technique for intermittent/indwelling). GI ● Tests: celiac testing, colonoscopy, ERCP, sigmoidoscopy, upper/lower GI series, upper endoscopy ● FOBT: dietary/med restrictions to prevent false positives (ex: beets, red meat, some veggies; aspirin/ibuprofen/Vit C) ● Stool culture: for severe/persistent diarrhea (travel, contaminated food/water, antibiotics) 13) Nursing Interventions Promote Urinary Elimination ● Bedpan/urinal assistance + measure output + privacy + skin check ● Bladder irrigation (ordered; pain is NOT expected → report) ● Lifestyle: avoid bladder irritants; appropriate fluids; weight loss; stop smoking ● Bladder training + elimination journal ● Bladder scan to avoid unnecessary catheterization ● Catheters: intermittent, indwelling, external male condom, external female wick ● CAUTI prevention: sterile insertion for indwelling/intermittent; daily hygiene; handwashing; keep system clean Promote Bowel Elimination ● Fiber, hydration, activity, respond to urge, stress management ● Bowel training (may use laxatives) ● Enemas: cleansing vs retention; solutions hypotonic/isotonic/hypertonic (tap water can cause electrolyte shifts) ● Laxatives: ○ Bulk-forming ○ Surfactant (stool softener) ○ Stimulant ○ Osmotic ● Rectal tubes/fecal management systems for severe incontinence Skin Care for Incontinence ● Clean promptly, rinse, pat dry ● Moisturize (alcohol-free) ● Barrier ointments/pastes/sealants ● Assess for nonblanchable redness, blisters, wounds/ulcers NG Decompression (for obstruction/ileus) Measure nose → ear tragus → xiphoid, advance with swallowing, confirm placement (x-ray/capnography/pH per policy), secure + suction as ordered. If you want, I can also turn this into a 1-page “exam cram” sheet (still including every concept, just in ultra-compact bullets). Condensed Study Guide: Main Concepts (Elimination + Sensory Perception) 1) ELIMINATION (URINARY + BOWEL) Urinary system basics ● Organs: kidneys → ureters → bladder → urethra ● Kidneys: filter blood, remove waste/fluid, regulate electrolytes & BP hormones, support RBC production. ● Normal urine: clear, light yellow, minimal odor. ○ Dark yellow/amber: dehydration. ○ Red/pink: blood or foods (beets). ○ Brown: severe dehydration/liver/kidney issues or certain foods. Expected urine output (high-yield) ● Adults: ~0.5 mL/kg/hr ● Output generally decreases with age (↓ nephrons, ↓ renal blood flow). Urinary alterations Urinary incontinence = can’t control urination Types: ● Stress: cough/sneeze/exertion → leak ● Urge: sudden strong urge → can’t reach toilet ● Overflow: bladder overfills from incomplete emptying → dribbling/leak ● Reflex: nerve damage → unpredictable leakage ● Functional: can’t get to toilet in time (mobility/dexterity issues) ● Nocturnal enuresis: nighttime bedwetting Key nursing focus: skin protection (barrier creams, briefs/pads), reduce irritants, bladder training, pelvic floor exercises. Urinary retention = can’t empty bladder fully ● Causes: BPH, prolapse (cystocele), obstruction (stones), neuro issues. ● Findings: hesitancy, weak stream, frequency, distention, pain, leakage. ● Risks: UTI, bladder/kidney damage. ● Interventions: identify cause, drain bladder if needed, bladder scan, catheterization if ordered. Common urinary conditions ● Dehydration: thirst, dry mouth, dizziness, dark urine, low urine; severe → IV fluids. ● UTI: dysuria, urgency/frequency; untreated → pyelonephritis (fever, flank pain, N/V). Treat: antibiotics + fluids. ● Kidney stones: severe flank pain radiating to groin, hematuria, N/V; treat pain + fluids, strain urine, possible lithotripsy/surgery. ● Kidney failure: ↓ urine, HTN, anemia, itching; treat dialysis/transplant. ● BPH: frequency/nocturia, weak stream, retention/incontinence; treat meds/surgery. Bowel system basics ● GI tract: mouth → esophagus → stomach → small intestine → large intestine → rectum → anus ● Peristalsis moves contents forward. ● Stool: should be soft/formed, easy to pass (no straining). Bristol Stool Chart (quick) ● 1–2: constipation (hard/lumpy) ● 3–4: ideal/normal ● 5–7: diarrhea (loose/watery) Bowel alterations ● Constipation: <3 BMs/week + hard stool/straining ○ Risks: impaction/obstruction (esp immobile/neuro injury). ○ Tx: fiber, fluids, activity, bowel training, stool softeners/laxatives; impaction → enema/manual removal. ● Diarrhea: frequent loose watery stools ○ Danger: dehydration, electrolyte imbalance; red flags: blood/black stool, fever, severe pain, lasts >2 days. ○ Tx: rehydration, remove irritants; meds like loperamide (if appropriate); infection → meds/probiotics as ordered. ● Bowel incontinence: urge (can’t reach toilet) vs passive (leak without awareness). ○ Nursing: skin care, scheduled toileting, bowel training, protect dignity. Diversions (know names + purpose) Urinary diversions ● Catheterization: intermittent or indwelling ● Ureteral stent: keeps ureter open ● Urostomy/ileal conduit: urine exits through stoma into pouch ● Nephrostomy: kidney → external drainage ● Cystostomy (suprapubic): catheter directly into bladder ● Neobladder/continent reservoir: internal storage; may need catheter to empty Complications: infection, skin breakdown, psychosocial stress. Fecal diversions ● Ileostomy: ileum → stoma (often liquid stool) ● Colostomy: colon → stoma (more formed depending on location) ● J-pouch: internal ileal reservoir connected to anus ● Kock pouch: continent ileostomy; catheter to empty Complications: skin irritation, leaks, hernia/prolapse, blockage, diarrhea, electrolyte issues. Diagnostic tests/specimens (high-yield) Urinary ● Urinalysis: dipstick + microscopic ● Urine culture: clean catch; susceptibility testing picks the right antibiotic ● 24-hr urine: measures substances over time ● Urodynamics: bladder function (uroflowmetry, PVR, cystometrics, etc.) ● Cystoscopy/ureteroscopy: visualize urinary tract GI ● FOBT: check hidden blood (avoid foods/meds that cause false positives) ● Stool culture: severe/persistent diarrhea, travel, prolonged antibiotics ● Colonoscopy, sigmoidoscopy, upper GI endoscopy, ERCP, GI series as indicated Nursing priorities (elimination) ● Assess: amount, frequency, color/odor, pain, stool type. ● Prevent skin breakdown: cleanse, dry, barrier creams, frequent checks. ● Promote normal patterns: hydration, fiber, activity, timed toileting, privacy, proper equipment (bedpan/urinal). ● Reduce infection risk: sterile technique for invasive catheters; minimize indwelling catheter days (CAUTI prevention). 2) SENSORY PERCEPTION (ALL MAIN CONCEPTS) Big picture ● Stimulus → sensory organ → CNS/cranial nerves → brain interprets → response ● Problems can be in reception, perception, or response. Key terms ● Sensory deficit: reduced function (vision/hearing/touch/etc.) ● Sensory deprivation: too little stimulation ● Sensory overload: too much stimulation → anxiety/confusion ● SPD: detects stimuli but brain misprocesses → oversensitive/overwhelmed Cranial nerves (only what’s essential) ● I smell, II vision, III/IV/VI eye movement ● V facial sensation/jaw ● VII facial expression + taste (front tongue) ● VIII hearing/balance ● IX/X swallowing/gag/voice ● XI shoulder shrug/head turn ● XII tongue movement Vision: most tested disorders ● Refractive errors: myopia, hyperopia, astigmatism, presbyopia ● Cataracts: cloudy lens → blurry/hazy, ↓ color ● Diabetic retinopathy: retinal vessel damage → floaters/blur → blindness risk ● Glaucoma: ↑ intraocular pressure → loss of peripheral vision (irreversible) ● Macular degeneration: loss of central vision (older adults) Tests: Snellen/Tumbling E; slit lamp; fluorescein angiography; visual field test; intraocular pressure; Amsler grid. Hearing ● Anatomy: outer → middle (ossicles) → inner (cochlea) → CN VIII. ● Tinnitus: ringing/buzzing without sound. ● Types of loss: ○ Sensorineural: inner ear/nerve (aging = presbycusis, loud noise, ototoxic meds) ○ Conductive: sound can’t travel (wax, otitis media, perforation, otosclerosis) ○ Mixed: both Tests: Rinne, pure-tone audiometry; ABR/OAE (screening). Speech/Aphasia (stroke-related high yield) ● Broca/expressive: understands but can’t produce words well (“telegraphic” speech) ● Wernicke/fluent: lots of words, no meaning; poor comprehension ● Global: severe impairment of both Touch ● Hypersensitivity / defensiveness (painful to normal touch) vs hyposensitivity (reduced pain/temp). ● Major causes: peripheral neuropathy (diabetic), spinal cord injury. ● Testing: neuro exam, sensation checks, nerve conduction, EMG, MRI. Smell & taste (often linked) ● Taste disorders: hypogeusia (↓ taste), ageusia (no taste), dysgeusia (metallic/rancid), phantom taste ● Smell disorders: anosmia (no smell), hyposmia (reduced), parosmia (distorted), phantosmia (smell not real) ● Causes: URIs, sinus disease, head injury, smoking, meds, zinc deficiency, neuro disorders. Aging effects (must know) ● Vision & hearing decline most. ● Vision: smaller pupils, less lens flexibility, weaker extraocular muscles, ↓ tears/dry eyes. ● Hearing: high-frequency loss, cerumen impaction, tinnitus. ● Taste/smell: ↓ taste buds + ↓ saliva → ↓ appetite → malnutrition risk. ● Touch: ↓ circulation → ↓ temperature/pain sensitivity. Nursing priorities (sensory) ● Safety + independence + emotional support ● Vision: lighting, corrective lenses, remove clutter, orient to room, fall prevention. ● Hearing: face client, reduce background noise, check hearing aids, use written info/interpreter. ● Speech: allow time, don’t finish sentences, use boards/paper/tablet. ● Touch: injury prevention (diabetic foot care, protective footwear, daily inspection). ● Smell/taste: oral hygiene, season foods, smoke/CO detectors, avoid smoking. If you want, I can turn this into a one-page “test-ready” version (even shorter, like only definitions + red flags + key interventions). Condensed Study Guide: Complementary & Integrative Health (CIH) / CAM / Holistic Nursing 1) Key Terms (know the differences) ● Conventional (Western) medicine: Evidence-based diagnosis & treatment (meds, surgery, radiation). Also called mainstream, allopathic, biomedicine, orthodox. ● Complementary therapy: Used with conventional care (ex: aloe + NSAID for sunburn). ● Alternative therapy: Used instead of conventional care. ● Integrative health: Combines conventional + complementary + alternative in a coordinated plan (mind–body–spirit). ● Holistic nursing: Client-centered care treating the whole person (physical, emotional, spiritual, social, cultural, environment). Focus is healing + wellness, not just curing disease. 2) NCCIH Categories (how CIH is “delivered”) Nutritional approaches ● Herbs/botanicals, supplements, vitamins/minerals, probiotics, dietary therapies ● Usually OTC and labeled as dietary supplements Psychological (mind–body) approaches ● Relaxation, meditation, mindfulness/MBSR, guided imagery, biofeedback, hypnosis, prayer Physical approaches ● Hands-on body structures/systems: massage, chiropractic, osteopathy, spinal manipulation, heat/cold, reflexology Bioenergetic (energy) therapies ● Veritable energy = measurable EM fields/light/magnets ● Putative energy (biofields) = subtle energy concepts ● Examples: Healing Touch, Therapeutic Touch, Reiki, Tai Chi, qi gong, acupressure Whole medical systems ● Complete systems separate from Western medicine: ○ Ayurveda, Traditional Chinese Medicine (TCM), Unani, Kampo ○ Also: Homeopathy, Naturopathy, Functional medicine (root-cause focus) Combined approaches ● Blends multiple categories: yoga, mindfulness eating, dance/art/music therapy 3) Why it matters (nursing relevance) ● Many clients use CIH (often alongside prescriptions). Nurses must: ○ Assess what clients use ○ Prevent interactions/harms ○ Provide culturally congruent care ○ Support self-care + empowerment ● Holistic nursing priorities ○ Promote wellness, honor caring–healing relationship ○ Respect subjective experience of illness/healing ○ Encourage informed decisions + active participation ○ Incorporate cultural beliefs/folk practices safely 4) High-yield Mind–Body Therapies (what they do) ● Deep breathing: control rate/depth → ↓ anxiety/stress ● Meditation: quiet mind/focused attention → ↓ BP/HR, ↓ stress effects ● Mindfulness: present-moment awareness; can reduce stress and improve coping ● Guided imagery: mental visualization → relaxation, pain/anxiety reduction ● Prayer: spiritual coping/connection (client-defined) ● Progressive relaxation: systematically tense/relax muscle groups ● Yoga (meditative movement): poses + breathing ± meditation → stress, sleep, anxiety; also pain (back/neck) support ● Aromatherapy: essential oils (inhaled/topical) → relaxation, anxiety relief; some evidence for nausea (ex: ginger/lavender/peppermint blends) ● Acupuncture/acupressure: stimulates points/meridians → pain, nausea, fatigue, anxiety support ● Hypnotherapy: focused attention + suggestion → phobias, anxiety, pain, habits (smoking) ● Biofeedback: device-assisted control of body functions (HR, tension) → stress, headaches, rehab, pain 5) Manual Therapies (hands-on) ● Massage: manipulates soft tissues → pain/anxiety/insomnia support ○ Precautions: avoid over clots/tumors/prostheses; caution with anticoagulants/low platelets (bruising/bleeding); older adults risk (rare) fractures ● Reflexology: foot/hand zones thought to correspond to body functions ● Chiropractic: spinal manipulation + structural focus; no surgery/Rx meds ● Osteopathic medicine: structure-function relationship; osteopathic manipulation used by trained physicians 6) Bioenergetic / Movement Therapies ● Tai Chi / Qi gong: meditative movement; balance, function, stress reduction ● Alexander Technique: posture/neck-spine alignment awareness → chronic pain support ● Feldenkrais: mindful movement retraining → pain + mobility ● Rolfing/Structural integration: deep tissue/fascia work → posture/function ● Pilates: core/torso control, posture → balance, flexibility, pain relief ● Therapeutic Touch / Healing Touch / Reiki: energy-based touch; may support relaxation, pain reduction, agitation (ex: dementia) 7) Traditional / Indigenous Practices (cultural competence) ● Traditional medicine (WHO concept): culture-based knowledge/practices for prevention/diagnosis/treatment—often includes spirituality. ● Examples: Native healing practices (prayer, drumming, storytelling, sacred rituals), herbal use, cupping, etc. ● Nursing: respect beliefs, ask what practices are important, integrate safely. 8) Whole Medical Systems (quick ID) ● Ayurveda: balance mind–body–spirit; doshas; cleansing + diet + herbs + yoga/meditation ● TCM: acupuncture, Tai Chi/qi gong, herbs; balance yin/yang + qi flow ● Naturopathy: “body heals itself” supported by diet, lifestyle, herbs, supplements, homeopathy, etc. ● Homeopathy: “like cures like,” highly diluted remedies ● Functional medicine: root-cause, systems-based approach 9) Natural Products: BIG SAFETY POINTS (test favorites) FDA/supplements ● FDA regulates supplements, but manufacturers are responsible for quality/claims → variability exists. ● “Natural” ≠ safe. Must-do nursing action ● Always ask about herbs/supplements/vitamins OTC. ● Encourage a current med + supplement list shared with provider/pharmacist before starting anything new. Common interaction themes ● Bleeding risk (esp with anticoagulants like warfarin): ○ Garlic, ginger, ginkgo, cranberry (large amounts), evening primrose oil, etc. ● Serotonin syndrome risk when mixing certain herbs with antidepressants: ○ St. John’s wort + antidepressants (ex: duloxetine) ● CNS depression/sedation combos: ○ Valerian + sedatives/alcohol/antihistamines ● Vitamin K decreases warfarin effect: ○ Leafy greens (consistency matters) Specific high-yield herbal cautions ● Ephedra (ma huang): banned in U.S. supplements → serious CVA/MI risk (worse with caffeine) ● Kava: can cause liver damage ● Black cohosh: possible liver injury risk ● Tea tree oil: toxic if ingested ● Licorice root: ↑ BP, can lower K+ (esp with diuretics); avoid in pregnancy ● St. John’s wort: many interactions (reduces effectiveness of multiple meds) + photosensitivity Probiotics (basic) ● Support healthy gut flora; can help inhibit harmful bacteria (ex: Lactobacillus) 10) Vitamins & Minerals (core test facts) Vitamins ● Water-soluble: B-complex + C (not stored well → need regular intake) ● Fat-soluble: A, D, E, K (stored in fat/liver → toxicity risk if too much) Vitamin K newborn note: doesn’t cross placenta well; newborns get IM vitamin K to prevent bleeding. B-complex quick purpose (big picture) ● Mostly metabolism/energy, neuro function, RBC formation ● B12: neuro + RBCs (deficiency → anemia, fatigue, neuro changes) Minerals (core roles) ● Needed for: enzyme function, nerve/muscle contraction, fluid balance, bone/teeth ● Examples: ○ Calcium: bones + clotting + nerve impulses ○ Sodium: extracellular fluid, nerve/muscle ○ Potassium: nerve/muscle; high/low can cause arrhythmias ○ Magnesium: metabolic processes; low with alcohol use disorder/DM ○ Iron: oxygen transport; deficiency → anemia Food-drug/nutrient interactions (quick) ● Vitamin C ↑ non-heme iron absorption ● Coffee/tea/wine (polyphenols) + phytic acid (legumes/nuts) ↓ iron absorption Quick “Exam-Style” Reminders ● Complementary = with conventional; Alternative = instead; Integrative = coordinated blend. ● Nursing role: assess use, prevent interactions, educate, support self-care, respect culture. ● Biggest safety issue: herb/supplement interactions (bleeding, serotonin syndrome, sedation, warfarin/vit K). If you want, paste any practice questions from this lesson and I’ll answer them using only what’s in your notes

mitochondria, lipid droplets, peroxisomes - lecture 13

NCLEX Precautions review; standard, contact, airborne, droplet

Culinary Dropout Menu

Liquid Biopsy Digital Droplet PCR article

Lipid droplet questions

cardio aerobic exercise dropout

Culinary Dropout Menu

Module 9 - Droplet PCR

Droplet Precautions

PPE precautions (droplet, contact, airborne)

curriculum Chương trình giảng dạy. Ex: Schools should update their curriculum to meet the demands of modern society. pedagogy Phương pháp giảng dạy. Ex: Modern pedagogy emphasizes student-centered learning. tuition fees Học phí. Ex: Many students are burdened by high university tuition fees. scholarship Học bổng. Ex: She received a full scholarship to study abroad. distance learning Học từ xa. Ex: Distance learning offers flexibility for working professionals. enroll in a course Ghi danh vào một khoá học. Ex: I decided to enroll in a course to improve my writing skills. literacy rate Tỷ lệ biết chữ. Ex: The government has made great efforts to improve the literacy rate in rural areas. academic performance Kết quả học tập. Ex: Poor nutrition can negatively affect a child’s academic performance. higher education Giáo dục bậc cao. Ex: Many believe higher education is key to a successful career. dropout rate Tỷ lệ bỏ học. Ex: The dropout rate in some developing countries is alarmingly high. continuous assessment Đánh giá liên tục. Ex: Continuous assessment encourages consistent study habits. vocational training Đào tạo nghề. Ex: Vocational training helps students gain practical skills for employment. compulsory education Giáo dục bắt buộc. Ex: In most countries, children must receive compulsory education until a certain age. tertiary education Giáo dục đại học/cao đẳng. Ex: Tertiary education opens up better job opportunities. learn by rote Học vẹt. Ex: Learning by rote is often criticized for not promoting deep understanding. interactive learning Học tương tác. Ex: Interactive learning makes lessons more engaging and effective. face-to-face classes Lớp học trực tiếp. Ex: Some students prefer face-to-face classes over online learning. extracurricular activities Hoạt động ngoại khoá. Ex: Extracurricular activities help develop teamwork and leadership skills. boarding school Trường nội trú. Ex: He spent five years in a prestigious boarding school in the UK. a well-rounded education Nền giáo dục toàn diện. Ex: A well-rounded education includes both academic

Dropout as a Bayesian Approximation

Droplet precautions/Thalassemia/Neoplasms

Culinary dropout WINE

Culinary Dropout FULL training menu

NCLEX Precautions review; standard, contact, airborne, droplet