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Body Temperature
Updated 15d ago
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System Interactions in Animals Tools Finish System Interactions in Animals The human body is made of many different organ systems. Each system performs unique functions for the body, but the systems also interact with each other to perform more complex functions. Major Organ Systems Body Systems In humans, cells, tissues, and organs group together to form organ systems. These systems each perform different functions for the human body. The major organ systems and their functions in humans include: The Nervous System — The nervous systems consists of two parts. The central nervous system consists of the brain and spinal cord, while the peripheral nervous system consists of nerves that connect the central nervous system to other parts of the body. The brain plays an important role in interpreting the information picked up by the sensory system. It helps in producing a precise response to the stimuli. It also controls bodily functions such as movements, thoughts, speech, and memory. The brain also controls many processes related to homeostasis in the body. The spinal cord connects to the brain through the brainstem. From the brainstem, the spinal cord extends to all the major nerves in the body. The spinal cord is the origin of spinal nerves that branch out to various body parts. These nerves help in receiving and transmitting signals from various body parts. The spinal cord helps in reflex actions of the body The smallest unit of the nervous system is the nerve cell, or neuron. Neurons communicate with each other and with other cells by producing and releasing electrochemical signals known as nerve impulses. Neurons consist of the cell body, the dendrites, and the axon. The cell body consists of a nucleus and cytoplasm. Dendrites are specialized branch-like structures that help in conducting impulses to and from the various body parts. Axons are long, slender extensions of the neuron. Each neuron possesses just a single axon. Its function is to carry the impulses away from the cell body to other neurons. The Circulatory System — The circulatory (or cardiovascular) system is composed of the heart, arteries, veins, and capillaries. The circulatory system is responsible for transporting blood to and from the lungs so that gas exchange can take place. As the circulatory system pumps blood throughout the body, dissolved nutrients and wastes are also delivered to their destinations. The heart is a muscular organ roughly the size of an adult human's closed fist. It is present behind the breastbone, slightly to the left. It consists of four chambers: right atrium, left atrium, right ventricle, and left ventricle. The heart receives deoxygenated blood from the body and pumps this blood to the lugs, where it is oxygenated. The oxygen-rich blood reenters the heart and is then pumped back through the body. The circulatory system is responsible for transporting blood to and from the lungs so that gas exchange can take place. As the circulatory system pumps blood throughout the body, dissolved nutrients and wastes are also delivered to their destinations. Blood circulation takes place through blood vessels. Blood vessels are tubular structures that form a network within the body and transport blood to each tissue. There are three major types of blood vessels: veins, arteries, and capillaries. Veins carry deoxygenated blood from the body to the heart, except for pulmonary veins, which carry oxygenated blood from the lungs to the heart. Arteries carry oxygenated blood from the heart to different organs, except for the pulmonary artery, which carries deoxygenated blood from the heart to the lungs. The arteries branch out to form capillaries. These capillaries are thin-walled vessels through which nutrients and wastes are exchanged with cells. The Respiratory System — The main structures of the respiratory system are the trachea (windpipe), the lungs, and the diaphragm. When the diaphragm contracts, it creates a vacuum in the lungs that causes them to fill with air. During this inhalation, oxygen diffuses into the circulatory system while carbon dioxide diffuses out into the air that will be exhaled. The trachea branches out into two primary bronchi. Each bronchus is further divided into numerous secondary bronchi. These secondary bronchi further branch into tertiary bronchi. Finally, each tertiary bronchus branches into numerous bronchioles. Each bronchiole terminates into a tiny, sac-like structure known as an alveolus. The walls of each alveolus are thin and contain numerous blood capillaries. The process of gaseous exchange occurs in these alveoli. The diaphragm is a dome-shaped muscle situated at the lower end of the rib cage. It separates the abdominal cavity from the chest cavity. During inhalation, the diaphragm contracts, and the chest cavity enlarges, creating a vacuum that allows air to be drawn in. This causes the alveoli in the lungs to expand with air. During this process, oxygen diffuses into the circulatory system while carbon dioxide diffuses out into the air that will be exhaled. On the other hand, expansion of the diaphragm causes exhalation of air containing carbon dioxide. The Digestive System — The digestive system consists of the mouth, stomach, small intestine, large intestine, and anus. It is responsible for taking in food, digesting it to extract energy and nutrients that cells can use to function, and expelling the remaining waste material. Mechanical and chemical digestion takes place in the mouth and stomach, while absorption of nutrients and water takes place in the intestines. The digestive system begins at the mouth, where food is taken in, and ends at the anus, where waste is expelled. The food taken into the mouth breaks into pieces by the grinding action of the teeth. Carbohydrate digestion starts in the mouth with the breakdown of carbohydrates into simple sugars with the help of salivary enzymes. The chewed food, known as a bolus, enters the stomach through the esophagus. The bolus mixes with acids and enzymes released by the stomach. Protein digestion starts in the stomach as proteins are broken down into peptides. This partially digested food is known as chyme. Chyme enters the small intestine and mixes with bile, a substance secreted by the liver, along with enzymes secreted by the pancreas. The digestion of fats starts in the small intestine as bile and pancreatic enzymes break down fats into fatty acids. The surface of the small intestine consists of hair-like projections known as villi. These villi help in absorbing nutrients from the digested food. The digested food enters the large intestine, or colon, where water and salts are reabsorbed. Any undigested food is expelled out of the body as waste. The Skeletal System — The skeletal system is made up of over 200 bones. It protects the body's internal organs, provides support for the body and gives it shape, and works with the muscular system to move the body. In addition, bones can store calcium and produce red and white blood cells. The Muscular System — The muscular system includes more than 650 tough, elastic pieces of tissue. The primary function of any muscle tissue is movement. This includes the movement of blood through the arteries, the movement of food through the digestive tract, and the movement of arms and legs through space. Skeletal muscles relax and contract to move the bones of the skeletal system. The Excretory System — The excretory system removes excess water, dangerous substances, and wastes from the body. The excretory system also plays an important role in maintaining body equilibrium, or homeostasis. The human excretory system includes the lungs, sweat glands in the skin, and the urinary system (such as the kidneys and the bladder). The body uses oxygen for metabolic processes. Oxygen metabolism results in the production of carbon dioxide, which is a waste matter. The lungs expel carbon dioxide through the mouth and nose. The liver converts toxic metabolic wastes, such as ammonia, into less harmful susbtances. Ammonia is converted to urea, which is then excreted in the urine. The skin also expels urea and small amounts of ammonia through sweat. The skin is embedded with sweat glands. These glands secrete sweat, a solution of water, salt, and wastes. The sweat rises to the skin's surface, where it evaporates. The skin maintains homeostasis by producing sweat in hot environments. Sweat production cools and prevents excessive heating of the body. Each kidney contains about a million tiny structures called nephrons, which filter the blood and collect waste products, such as urea, salts, and excess water that go on to become urine. The Endocrine System — The endocrine system is involved with the control of body processes such as fluid balance, growth, and sexual development. The endocrine system controls these processes through hormones, which are produced by endocrine glands. Some endocrine glands include the pituitary gland, thyroid gland, parathyroid gland, adrenal glands, thymus gland, ovaries in females, and testes in males. The Immune System — The immune system is a network of cells, tissues, and organs that defends the body against foreign invaders. The immune system uses antibodies and specialized cells, such as T-cells, to defend the body from microorganisms that cause disease. The Reproductive System — The reproductive system includes structures, such as the uterus and fallopian tubes in females and the penis and testes in males, that allow humans to produce new offspring. The reproductive system also controls certain hormones in the human body that regulate the development of sexual characteristics and determine when the body is able to reproduce. The Integumentary System — The integumentary system is made up of a person's skin, hair, and nails. The skin acts as a barrier to the outside world by keeping moisture in the body and foreign substances out of the body. Nerves in the skin act as an interface with the outside world, helping to regulate important aspects of homeostasis, such as body temperature. Interacting Organ Systems The organ systems work together to perform complex bodily functions. The functions of regulation, nutrient absorption, defense, and reproduction are only possible because of the interaction of multiple body systems. Regulation All living organisms must maintain homeostasis, a stable internal environment. Organisms maintain homeostasis by monitoring internal conditions and making adjustments to the body systems as necessary. For example, as body temperature increases, skin receptors and receptors in a region of the brain called the hypothalamus sense the change. The change triggers the nervous system to send signals to the integumentary and circulatory systems. These signals cause the skin to sweat and blood vessels close to the surface of the skin to dilate, actions which dispel heat to decrease body temperature. Both the nervous system and the endocrine system are typically involved in the maintenance of homeostasis. The nervous system receives and processes stimuli, and then it sends signals to body structures to coordinate a response. The endocrine system helps regulate the response through the release of hormones, which travel through the circulatory system to their site of action. For example, the endocrine system regulates the level of sugar in the blood by the release of the hormones insulin, which stimulates uptake of glucose by cells, and glucagon, which stimulates the release of glucose by the liver. The nervous and endocrine systems interact with the excretory system in the process of osmoregulation, the homeostatic regulation of water and fluid balance in the body. The excretory system expels excess water, salts, and waste products. The excretion of excessive amounts of water can be harmful to the body because it reduces blood pressure. If the nervous system detects a decrease in blood pressure, it stimulates the endocrine system to release antidiuretic hormone. This hormone decreases the amount of water released by the kidneys to ensure appropriate blood pressure. Appropriate levels of carbon dioxide in the blood are also maintained by homeostatic mechanisms that involve several organ systems. Excess carbon dioxide, a byproduct of cellular respiration, can be harmful to an organism. As blood circulates throughout the body, it picks up carbon dioxide waste from cells and transports it to the lungs, where it is exhaled while fresh oxygen is inhaled. If the concentration of carbon dioxide in the blood increases above a certain threshold, the nervous system directs the lungs to increase their respiration rate to remove the excess carbon dioxide, which ensures that the levels of carbon dioxide in the blood are maintained at appropriate levels. In this way, the circulatory, respiratory, and nervous systems work together to limit the level of carbon dioxide in the blood. Nutrient Absorption To absorb nutrients from food, the nervous, digestive, muscular, excretory, and circulatory systems all interact. The nervous system controls the intake of food and regulates the muscular action of chewing, which mechanically breaks down food. As food travels through the stomach and intestines, the digestive system structures release enzymes to stimulate its chemical breakdown. At the same time, the muscular action, called peristalsis, of the muscles in the wall of the stomach help churn the food and push it through the digestive tract. In the intestines, nutrients from food travel across the surfaces of the villi. The nutrients are then picked up by the blood, and the circulatory system transports the nutrients throughout the cells of the body. The endocrine system releases hormones, such as insulin, that control the rate at which certain body cells use nutrients. Any excess minerals, such as calcium, in the blood are deposited in and stored by the skeletal system. Waste products produced by the use of nutrients, as well as the leftover solid waste from the digestion of food, exit the body through the excretory system. Throughout the process of nutrient absorption, the nervous system controls the muscles involved in digestion, circulation, and excretion. Defense Several body systems interact to defend the body from external threats. The body's first line of defense is the integumentary system, which provide a physical barrier that prevents pathogens from entering the body. The skin of the integumentary system also contains receptors for pain, temperature, and pressure. If an unpleasant stimulus is encountered, these receptors send signals to the central nervous system. In response, the central nervous system sends commands to the muscles to move the body part away from the stimulus. In this way, the integumentary, nervous, and muscular systems interact to prevent damage to the body. In the event of a break in the skin, the nervous, immune, lymphatic, and circulatory systems work together to repair the wound and protect the body from pathogens. When the skin is broken, specialized blood cells called platelets form a clot to stop the bleeding. These platelets also release chemicals that travel through the circulatory system and recruit cells, like immune system cells, to repair the wound. These immune cells, or white blood cells, are transported by the circulatory and lymphatic systems to the site of the wound, where they identify and destroy potentially pathogenic cells to prevent an infection. Some lymphocytes, white blood cells produced by the lymphatic system, also produce antibodies to neutralize specific pathogens. All of the white blood cells involved in the body's response were originally produced in the bone marrow of the skeletal system. If an infection does occur
Updated 34d ago
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Know the relationship between molecular weight and rate of diffusion The rate of diffusion is inversely proportional to the molecular weight Small weight-fast diffusion; heavy weight-slow diffusion Identify RBC’s in various solution and determine tonicity Tonicity - the ability of an extracellular solution to make water move into or out of a cell by osmosis If a cell is placed in a hypertonic solution, there will be a net flow of water out of the cell, and the cell will lose volume (shrink). A solution will be hypertonic to a cell if its solute concentration is higher than that inside the cell, and the solutes cannot cross the membrane. If a cell is placed in a hypotonic solution, there will be a net flow of water into the cell, the cell will gain volume (bigger). If the solute concentration outside the cell is lower than inside the cell, then solutes cannot cross the membrane, then the solution is hypotonic to the cell. If a cell is placed in an isotonic solution, there will be no set flow of water into or out of the cell, and the cell’s volume will remain stable. If the solute concentration outside the cell is the same as inside the cell, and the solutes cannot cross the membrane, the solution is isotonic to the cell. Homeostatic feedback loop for respiratory rate, heart rate and temperature Respiratory Rate: Stimulus : The level of carbon dioxide (CO2) in the blood increases (often due to exercise or hypoventilation) . Receptors: Chemoreceptors in the medulla oblongata, carotid arteries, and aortic arch detect changes in blood pH and CO2 levels Control Center: The medulla oblongata processes this information Effectors: Respiratory muscles (diaphragm and intercostal) adjust breathing rate and depth Response: Increased respiratory rate removes CO2 and increases O2 intake, restoring normal pH and gas levels. Heart Rate: Stimulus : Changes in blood pressure, O2, CO2, or pH levels Receptors: Baroreceptors (detect blood pressure changes) in the carotid sinus and aortic arch; chemoreceptors monitor blood chemistry Control Center: The medulla oblongata (cardiac center) processes signals Effectors : The autonomic nervous system (ANS) adjusts heart rate through the sympathetic nervous system (increases heart rate) or parasympathetic nervous system (decreases heart rate) Response : Heart rate increases during low O2 or low blood pressure (to circulate oxygen) and decreases when homeostasis is restored. Temperature Regulation Stimulus: Changes in body temperature (hyperthermia or hypothermia) Receptors: Thermoreceptors in the skin and hypothalamus detect temperature fluctuations. Control Center: The hypothalamus processes this information and signals effectors Effectors and Responses: If too hot: Blood vessels dilate (vasodilation) to release heat, and sweat glands produce sweat for cooling If too cold: Blood vessels constrict (vasoconstriction) to retain heat, and shivering generates warmth. Steps of a generic homeostatic feedback loop Stimulus : A change in the internal or external environment that disrupts homeostasis (eg. temperature change, pH levels, blood sugar levels) Sensor (Receptor) : Specialized cells or receptors detect the change and send information to the control center. Control Center (Integrator): Often the brain or endocrine glands, this component processes the information from the sensors and determines the appropriate response to restore balance. Effector: This component carries out the response to the stimulus as dictated by the control center. Effectors can be muscles or glands that help to counteract the change. Response: The action taken by the effectors to restore homeostasis. This could involve increasing or decreasing a physiological process (e.g. sweating to cool down or shivering to warm up) Feedback: The results of the response are monitored. If homeostasis is restored, the system maintains its state; if not, the loop may repeat, continuing to adjust until balance is achieved. How to evaluate data to determine the set point, error, and disturbance Identify the set point The set point is the optimal level or range that the system aims to maintain. To determine the set point: Gather baseline data: Collect data over a period to understand the normal range for the variable in question (e.g. body temp., BP, blood glucose levels) Analyze Trends: Look for patterns in the data to identify the average or median value that represents the stable condition of the system. Consult Literature: Reference established physiological norms or previous studies to confirm the typical set point for the variable. Assess Disturbance A disturbance is any factor or event that causes a deviation from the set point. To evaluate disturbances: Identify External and Internal Factors: Analyze the data for any external influences (e.g. environmental changes, dietary habits) or internal changes (e.g. illness, stress) that might have impacted the variable. Quantity Disturbance: Measure the magnitude and duration of the disturbance. This can be done by comparing the data points during the disturbance against the established set point. Monitor Changes: Track how the system responds to disturbances over time to assess their impact on maintaining homeostasis. WBC types and normal distribution values/ abnormal values and what those values indicate (infections/diseases) (Never Let Monkeys Eat Bananas) Neutrophils (50-70%) - First responders to infections, especially bacterial. High levels indicate bacterial infections, inflammation, or stress. Low levels can indicate bone marrow disorders or severe infections. Lymphocytes (20-40%) - Include B cells and T cells, important for immunity. High levels can suggest viral infections or leukemia, while low levels might indicate immune deficiency. Monocytes (2-8%) - Help with cleaning up dead cells and fighting infections. High levels can be linked to chronic infections or autoimmune diseases. Eosinophils (1-4%) - Involved in allergic reactions and fighting parasites. Elevated levels may indicate allergies or parasitic infections. Basophils (0.5-1%) - Release histamine during allergic reactions. High levels might be see in allergic conditions or blood disorders. Normal WBC Count Total WBC Count: 4000-11000 cells per microliter of blood (varies slightly by lab) Leukocytosis (High WBC): Can indicate infection, inflammation, stress, or leukemia Leukopenia (Low WBC): Can result from bone marrow disorders, viral infections, or autoimmune diseases Neutrophils: Banded vs Segmented Neutrophils are the most abundant type of white blood cells and play a crucial role in fighting infections. They exist in different stages of maturation: Banded Neutrophils (“Bands”) - Immature Neutrophils Appearance: Have a curved, unsegmented nucleus (band-shaped) Normal Range: 0-6% of total WBC count (~0-700/uL) Clinical Significance: Increased Bands (Bandemia) -> Indicates an acute bacterial infection or severe stress (e.g. sepsis). The bone marrow releases immature neutrophils in response to infection. Low Bands -> Not clinically significant unless the total WBC count is low, which could suggest bone marrow suppression. Segmented Neutrophils (“Segs”) - Mature Neutrophils Appearance: Have a segmented nucleus with 2-5 lobes Normal Range: 50-70% of total WBC count (~2500-7000/uL) Clinical Significance: High Segs (Neutrophilia) -> Suggests bacterial infections, stress, chronic inflammation, or leukemia Low Segs (Neutropenia) ->Can be caused by viral infections, bone marrow disorders, chemotherapy, or autoimmune diseases. Discuss the stages of cell cycle/mitosis-which stages are longest/shortest The cell cycle is a series of events that cells go through to grow and divide. It consists of two main phases: Interphase (Longest Phase) – Preparation for division Mitosis (Shortest Phase) – Actual cell division Stages of the Cell Cycle Interphase (90% of the Cell Cycle – Longest Phase) Interphase is the period of cell growth and DNA replication. It has three subphases: G1 Phase (Gap 1) The cell grows, produces proteins, and prepares for DNA replication. Longest variable phase; some cells may stay here indefinitely (e.g., neurons in G0 phase). S Phase (Synthesis) DNA replication occurs, ensuring each daughter cell gets a complete genome. Takes about 6-8 hours in human cells. G2 Phase (Gap 2) The cell prepares for mitosis by producing proteins and organelles. Shorter than G1 but still significant in length. Mitosis: Prophase, Metaphase, Anaphase, Telophase Know proportional and inversely proportional relationships Direct (Proportional) Relationship When two quantities increase or decrease together at a constant rate, they are directly proportional. Inversely Proportional When one variable increases, the other decreases proportionally. Know relationship between molecular weight and rate of diffusion The rate of diffusion of a substance is inversely proportional to the square root of its molecular weight. Lighter molecules diffuse faster Heavier molecules diffuse slower due to greater mass. Know relationship between filtration rate and pressure of fluid or weight of fluid Filtration rate is directly proportional to the pressure or weight of the fluid driving the filtration process. Higher pressure → Higher filtration rate Lower pressure → Lower filtration rate Know why men and women blood values are different The differences in blood values between men and women are due to biological, hormonal, and physiological factors
Updated 53d ago
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Sports & Exercise Science Lectures History of Sport and Exercise Science, highlighting relevance of training principles today. • Historian part of speaker finds interest in history of Sport and Exercise Science. Sport and exercise science history and its evolution. • Sport Science: Systematic approach to understanding factors relating to sports performance. • Exercise Science: Systematic approach to understanding how the human body responds to physical activity. • Agriculture led to sedentary lifestyle and exercise became a way to combat it (0:03:14) • Ancient Chinese philosophers like Confucius and Hippocrates advocated for exercise as a means of maintaining health (5000 years ago) Exercise science history, including Leonardo da Vinci's anatomical sketches and early physiology experiments. • Leonardo da Vinci (1500s) made accurate anatomical sketches, discovering heart as muscle pump and nervous system hierarchy. • William Harvey (1600s) discovered blood circulation in one direction, and Boyle (1600s) found Boyle's law, which explains breathing mechanism. • Johan Bernoulli (1700s) developed mathematical models to explain muscle mechanics, using tractors to investigate muscle contractions. • James Lin discovered the origins of scourgia by inviting vitamin C-rich food, with great success. • Anton Laviesia named oxygen and recognized hydrogen as an element, and his experiments on human respiration led to a better understanding of metabolism and nutrition. Note Sport and Exercise Science sub-disciplines and their roles in sport and clinical contexts. • Sport and Exercise Science sub disciplines explore roles in sporting and clinical contexts (psychologists, biomechanics, nutritionists, strength coaches, physiologists, performance analysts) • Accredited Exercise Physiologists provide individualized exercise programs for high-risk populations (hypertension, heart disease, diabetes, musculoskeletal conditions, injuries) Exercise physiology and biomechanics in sports. • Exercise physiologist specializes in prescribing exercise for patients with chronic diseases or injuries. • Sports physiologist studies the physiological demands of sports and advises athletes on training and competition. • Biochemist analyzes technique and injury mechanisms in sports, measuring mechanical loads and risk assessments. Improving athletic performance through strength training and conditioning. • Unknown Speaker discusses biomechanics and jumping throws, using a three-mesh Castle system to measure angles, velocities, and selections of throwing motion. • Strength and conditioning coach works with athletes to improve strength, power, speed, fitness, acceleration, agility, endurance, and flexibility. • Coach designs programs to reduce injury risk, optimize recovery, and deliver rehab programs in conjunction with medical staff for injured athletes. Motor control, learning, and performance in sports. • Motor control specialists focus on learning, performing, and retaining motor skills over time. • Sport psychologists help athletes overcome barriers to optimal performance, using techniques like visualization and mindfulness. Sports dietitians' role in optimizing athletes' health, performance, and nutrition. • Sports dietitians tailor nutritional strategies for athletes to optimize health, performance, and body composition. • Dietitians recommend food first approach and supplements when necessary, and provide individualized advice and hydration stations. • Unknown Speaker discusses six specialist supplements in Sport and Exercise Science, including nutrition (12:30) • Speaker shares insights on interdisciplinary approach to high performance in surfing, with focus on strength conditioning and sport science (14:45) Functional Anatomy an understanding of how to use a correct terms to describe movement interaction, understand major bones, muscles, joints, and how they work together in human movement, and begin to develop the ability to form a movement. Analysis of exercise and supporting tasks. Despite in this lecture, if you're unfamiliar with anatomy, it might require a second viewing. Beautiful lecture is the ability to stop review. If you require any further help with the content, please reach out to your tutor. So the first thing I understand in anthropical language is that whenever we refer to position or something, we're referring to it in its position when in the anatomical position. So this is the standardized position of the body where it is always direct and facing forwards, with the palms of the side of the body, toes and palms of the hands facing forwards. Having a standard anatomical position is crucial to reference and describe the relationship of body sequence to one another when it is anatomical position. There are three COVID plans from which we can view or segment the body that is essential, frontal and reverse plastics. So the station plane, or the median plane, is the side on view of the body, meaning you see a profile of the person. The frontal plane is also called the corona plane, and there's the view we get between directly at the front or back of the body. And finally, the transverse plane, also called the horizontal plane, is the birds of view of the body. There generally can be from the ground up as well, right, if it's never nearly achieved. And the other understand that the body can be viewed in three different planes. It's relatively straightforward to understand that rotational movement also occurs in each of these three axes. So this is called an axis of rotation, and is essentially an imaginary line about which any rotational movement occurs perpendicular to that Cardinal plane of action, just like the anatomical position and Cardinal planes allow us to describe the relative positions with different body parts. So it doesn't understand axis of rotation allows us to constantly describe human movement. However, most movements of human body typically occur about two or more axes of rotation, which makes the analysis of human movement far more challenging. So you think about the 3x Y and Z plane take elbow flexion like a bicycle. When view from front and the front plane, it looks like the forearm hand is simply moving up towards the face, open, viewed side on from the sagittal plane, you see that the forearm hand also moving away from the body and then back towards the body as it goes through that arc. Movement. This way to understand all three other anatomical positions, the counter planes and the axes of rotation, to be able to accurately describe pure movement. So now we can consider best view in his plans. So in the anatomical position, the most common actually the rotation between the SAP flexion and extension. And we'll go through that few slides for now. Include flexion and extension at the wrist, elbow, shoulder, neck, trunk, hip, knee and ankle. At the ankle. It's also referred to as dorsi flexion and plantar flexion, rather than flexion extension. Multi joint actions can involve both. So kicking your foot forwards involve flexing the hip, swinging forward and extending in the knee. Some of that actually rotation. Best views in the frontal plane include adduction and abduction at the shoulder and hip, lateral flexion at the neck and trunk, as well as radial and ulna deviation at the wrist and diversion and inversion at the ankle. And this is why I move the mechanism, which can result in raw ego the arm actually in breast stroke. Swing is adduction, kicking a stop or the ring forward involved adduction of the hip. Two legs coming together are being added so that's adduction. When the arm is being taken away from the body, it is being abducted. It's been taken away. Finding the transverse plane. Some of the best view axes of rotation and movements include internal and external rotation of the shoulder and hip, and horizontal adduction and abduction for the shoulder and the forearms, pronation and supination and neck and trunk rotation. Each of these three slides are diagrams. Highlight the movements just went through. The next slide go through the names of these moves and what the actions are. Flexion and extension refer to increasing and decreasing the angle in the frontal plane. So for instance, elbow flexion is raising your forearm and hand, while extension is lowering back down. This is truthfully all flexion extension, except for the ankle, which you remember dorsiflexion and plantar flexion. So dorsiflexion refers to moving the top of the foot towards the leg, and plant deflection is away from the leg towards the ground. I find this easier to remember using your plan to flexion as the movement required to step on a plane with your toes. Adduction. And adduction refer to moving away or towards the central plane. Next is protraction and retraction. This is moving something forward or patterns. And a good example is the second level of shoulder blades. When you pull your shoulder blades back and away. This is attraction. Protraction is the opposite elevation and depression. Can be also thought of with regarding the shoulder is raising, like in a shrug, while depression is lowering back down another shoulder blade sample is upward and downward rotation, with upward rotation referring to the rotational movement around access to a point superior and downward rotation, maybe opposite. Medium and lateral rotation referred to rotating toward or away from midnight. So the arms hanging medial rotation is internal rotation of your arm, the shoulder towards midnight, and external or lateral rotation being back away from midnight. Pronation suppression has special terms for forearm movement. With a forearm rotation to have your palm facing upward in an anatomical position in front of supreme and the back of your hands facing forward into pronation. We can also use these terms of the foot, but they are known as inversion, meaning the sole of the foot faces towards mid level E version, when the solar foot rolls away from the middle. Our last two terms, especially with the circumduction, referring to the combination of flexion and attention abduction and medial lateral rotations, and often we could curtain rally, but when we move up arms or legs, it's usually not in a single plane through a multiple plane with multiple positive move and social conduction despises. Now opposition is the movement of bringing tips of your fingers and thumb together. And the reason we also have possible thumbs are very useful with lasers pick up items. Here is a diagram illustrating protraction, retraction, elevation and depression, these lines of upper rotation and downward rotation. So on this slide is a consolidated view of some special actions that only currently in places. So we've got scapular to demonstrate protraction, retraction, depression, elevation, plus upward and downward rotation. You can see that you can invert or divert the ankle. In running terms, we can talk about pronation as collapsing inwards during foot strike, which means I saw the foot faces away from midline. Next is illustrate example of plantar flexion and dorsiflexion and ankle, and define this example of protraction, retraction, elation and depression of the Mandal which is the lower jaw bone. So you would think that with each member of the move toward or away from the midline, or up versus down, all these things, or have anatomical terms to solve the time in terms of the direction of body. So anterior and posterior refer to the front and back of the body in atomic position. You also call them ventral end dorsal, and think of dorsalism, but the dorsal is the dorsal fin on the back, mostly we refer to as anterior and posterior. Superior and inferior refer to the directions towards the head or towards the feet, while medial and lateral refer to the direction towards the midline or away from midline in a sideways direction, approximately distal, our special tendencies to refer to the relative positioning of something compared to another landmark. So if something is distal, it refers to sides located away from a specific area, most often the center of body, and for instance, the hand is visible to the elbow. Proximal refers to sites located towards a specific area, so the COVID The elbow is proximal to the hand. The term distal, or is maximum or distance or proximal indicates proximity. Now last terms are superficial and deep, which require you to think in three days. So something that's superficial is close to the surface or the skin of the body, or something that's deep is away from so muscles are deep to the skin, but superficial to bone. So many of these will become important when we talk about anatomy, as certain structures can be proximal or anterior or superficial to other structures. The human anatomy is built around the scaffolding of the split system. So this slide shows you in the structure an anatom. We're not going to go through that in this lecture for this electron. Functional anatomy is more important than understand the function of the skeleton that bones make up, beyond just being the strong structure holding us together, the way the bones fit together and serve as attachment points for the ligaments, tendons and muscles, serves to allow various movements of the body that we've already discussed. The skeleton by the rib cage also protects wild organs, while the internal structure of the bone allows for the storage of minerals and production of new blood cells. We wouldn't have any of the functional movements we've discussed so far without having a skeleton to support these movements. There are 206, bones in the human body. We don't need to learn them all, but we're certainly discussing some of them in this unit. So basic understanding of the major structure of the skeleton is important, and you can use this as a reference for some of those major bones. In this particular image, the green bones represent the actual skeleton, and the non green turn the perpendicular skeleton thanks to better understand how movement can occur in the body. Is cartilage, which is a stiff but flexible connective tissue found in many applications throughout the body. So cartilage is composed of specialized cells called corona sites. They produce a large amount of extracellular matrix. So cartilage can be classified as three types. We have hyaline cartilage, which forms a smooth surface on articular joint surfaces, with Fibro cartilage that is a part of form of cartilage found at sites such as the pubic symphysis. And you've got elastin cartilage, which can be found in here. Cartilage doesn't actually contain blood vessels instead, the chondrocytes are supplied by diffusion, which is helped by the pumping action generated by the compression of articulate cartilage or flexion of the elastic charge. So because it doesn't have a blood supply, cartilage grows and repairs more slowly, which is why cartilage injuries are so slow to healing athletes and and often require arthroscopic surgery, which are inelastic but flexible bands of connective tissue that attached, attached two bones together so they enhance joint stability by maintaining the alignment of bones and limiting range of motion. Those are the two primary functions keep bone and enhancement stability. The most common injuries involve involving into sprains, which means over stretching and tearing of the fibers, and they can be quite slow to heal. So if we bring that together, we get a joints so these facilitate the movers that we discussed at the front of this lecture, per muscular structure, joined by the ones, separate by cartilage. The form joints, which used to be also called articulations. There are three types of classifications of joint. So we have fibrous joints, which are bound by dense connective tissue. And these are joints in the scale, and they really don't move much. You have a catalyst joint, which, as the name suggests, is a joint with fibrous cartilage separating two bones, such as the symphysis, pubis and the ribs. And again, they don't move very much. And then finally, we have synovial joints, which are bound by a joint capsule in containing ligaments and muscles to allow them to occur. And these are the ones with most interesting in this lecture. So not only a synovial joints most interesting for me, but also the most common type of joint. So the articulate capsule, which surrounds synovial joint forms a kind of SAC around the joint. And so there's also synovial membrane inside the articulate capsule, which secretes synovial fluid, and this lubricates the articular cartilage of the joint services, similar to enjoy car lubricating the moving parts. It also nourishes the joint structure, and it can act as a shock absorber, distributing the stress evenly across the articular surface. So all of this combines to allow for smooth fluid movement joints, and usually without needing an oil change during your lifetime, as we've already gone over, the bones with the joints are held together by ligaments. But what we haven't talked about here is the joints can also contain something else called a bursa, which we'll discuss a bit later. So even though synovial joints are major type of joint, they can also be classified with various types of synovial joints. So we have plain joints, which can be found in the joints between the vertebral articulating surfaces. We've got hinge joints such as the elbow or the knee. We have pivot joints such as the ulnar and radius. We have COVID joints in the fingers. We have several joints, which is the thumbnail and sub joint, such as the hip and joint. Okay, so this is a very useful slide for a reference for various locations where these joints can be found. As I mentioned before, we have bursa which can sometimes occur with some synovial joints. These are small sacks of fibrous tissue filled with synovial fluid, and they are found where different parts move over one another in the body, and they help reduce friction within the joint. So these mostly occur with bones, ligaments, muscles, skin or tendons, over later, and will rub together. If a person comes in flames, it can lead to an injury you might have heard for bursitis, where the bursar releases too much fluid and the joint gets very swollen, and they can make movement difficult. So burst sit around tendons, and so that's the next structure that we look at. So tendons are tough but flexible bands of tissue that attach muscle to bone and help facilitate movement. So like many fibrous structures we've already discussed, they have a limited blood supply, which makes healing and repair slow. Some common tenderness injuries, which are strains or over stretching. Can be a tenderpathy or tenderloin, which is a result of inflammation, and tenderlois, which is a chronic inflammatory condition. Lastly, we have the muscles, and as with the bones, you'll do need to understand some of the basic muscles of the body, but for the for this functional anatomy component, we'll just talk about the functions of the skeleton worker. So essentially, our muscles control our posture. They provide support for the soft tissues in the body. They allow the body to store energy to use during movement exercise. They can guard entrances and agents in the body, and they also produce heat to allow us to regulate our body temperature. When muscle is contracted, it pulls on the tendon of the muscle, which in turn is connected to the bones, bone, and then we get the movement. So the way in which that occurs in a single muscle cell fiber is made up of many myofibrils, which can make up any starters. So within the start of me there's actin and myosin filaments, and that's called an actin mycin cross bridge. And they slide past and pull each other closer together or further to control the movement. So whilst we're over the 700 muscles in the body, here's a list of some of the major muscles that we'll refer to, and you'll cover it in a different unit, but certainly will be exposed as many of these throughout the labs. So reaching the end of this lecture, we now have to use the knowledge from this lecture to answer some applied problems. So during stationary cycling, what plane or planes of movement is this exercise occurring? So what axis of rotation is movement occurring? So we will need to look at a sporting movement or an exercise and describe it in its proper anatomical terms, so not always as simple as stationary cycling. So take this diagonal Wood Chop exercise as an example. This is still quite a basic movement. If there are multiple axes of rotation occurring through multiple planes involving many joints, bones and muscles. And even in a more complex example, we can go to Goldsmith and see movement across multiple axes of rotation of all three planes. For example, the frontal plane, we can see abduction and abduction, as well as inversion and inversion. In the Sagitta plane, we can see flexion and extension in the medial lateral axis. On the transverse plane, we can see rotation around the longitudinal latches. Many real world supporting movements will be like this, involving a complex coordination of many movements across many planes. We will work through all of these in the labs. So to be able to describe all of these different actions using proper environmental terminology, I highly recommend you start the voting time to study with most of your three credit point units. You'll find that towns a week is allocated for full time state, only four hours of that is lectures and labs, which leaves the rest of your time for state. So please use that time, why is it, this particular left of today on functionality, you may have many questions about plans of movement anatomical terms. I'm trying to write them down, bring them to the lab so that we can speak to your tuners about their experiences with learning this material. Thanks for watching this lecture. Body compostion In this lecture, we will cover body composition, the different types of tissue in the human body, and how these are distributed, measured and the impact on our health. of this lecture, you'll have an understanding of the components of body composition and implications of body composition on health. So body composition is the general term that refers to the relative amounts of tissue types of the body, generally related to fat and fat free mass. It is expressed as a percentage of body fat. There are general classifications of body composition, from underweight to severely obese. Body Composition is related to general health and can also have an impact on supporting performance. The assessment of body composition can be used to monitor lifestyle interventions. There are optimal ranges for health and exercise. Professionals administer different Exercise and Nutritional strategies to influence body composition. There any correlations between risk of chronic disease and body position, including coronary heart disease, diabetes, hypertension, some cancers, hyperlipidemia is more commonly referred to as high cholesterol, but encompasses several blood lipids. Body Mass Index is one measure of obesity as a relationship between height and weight. On this low we can see the relative risk of type two diabetes starts increasing rapidly between BMI 25 to 30, which is Catia crisis, overweight, and beyond, which is obese. We can see on the right side that the same relationship holds true for many forms of cancer. Delicately, this pilot, diabetes and cancer can be thought of as lifestyle diseases, and that body composition is one factor which is correlated with the risk of these diseases. Here we can see the five different lenses through which to view body composition. So at the time level, we mostly hydrogen and oxygen, the word elements on a carbon skeleton with trace elements making it the rest. At the molecular level, we mostly water with fats, proteins and minerals making up the remainder. At the cellular level, where you predominantly cell mass, extra cellular solids, that's ECS, that ECF is extra cellular fluids and fat. And functionally, which we're most often interested is joint modify is muscle and fat, and then other substances like blood and bone. So within the functional assessment of body composition, there are a number of different models that can be used to describe body composition. As we can see, whether we're using a two, three or four component model, the common factor is fat mass. So different techniques are required for different analyzes, but most techniques can identify fat mass or a fat percentage analysis. So while fat is a common denominator between these different assessments of body composition, there are still different types of fat. So optimal fat is critical for optimal health. It is necessary for healthy cell and system function. At the minimum, it's 3% for men and 12% for women. Fat can be stored under the skin, known as subcutaneous or visceral fat, and deeper fat around the organs. It's the visceral fat that can be the dangerous for health due to its proximity to the organs. Here are a number of different ranges for recommended levels of body fat, but broadly speaking and optimum body fat percentage could be generalized to be between eight and 35% if you're unsure what these different levels of body fat look like, This slide provides a rough depiction of how body shapes change with increasing levels of body fat. For similar levels of body fat percentage, there are different fat distributions referred to as Android fat, or going away fat core locally there's the apple or pear body shape. The Android shape is more associated with health risk as the fat is stored around the organs. So humans are becoming increasingly overweight innovative. This is due to a number of reasons, but it can be summarized simply, as we are consuming more of energy. As wealth increases and high energy convenience foods become more prevalent, we're also burning less and less energy as tasks which were typically performed manually and burned like calories, and they are performed by technology machines. So this combination of more energy being consumed and less being burned has resulted in an explosion in obesity that's particularly in wealthy first world countries, and with that, an increase in preventable chronic diseases. So as many physical characteristics, there is a genetic component, and there are rare forms of obesity that are result of gene mutations which influence appetite or energy homeostasis. However, given that human genetics have changed little in the past 50 years, and obesity rates have increased significantly, the impact of genes on obesity are quite small. Instead, lifestyle choices driving the change in obesity rates, the magnitude of chronic health conditions associated with obesity are large, expensive and largely preventable, so being overweight has been demonstrated to impact cardiovascular disease, cancer, high blood pressure, hypertension and type two diabetes. Type Two Diabetes is a situation where the body becomes resistant to insulin. Type one diabetes is an unable genetic condition that usually in young people, where the body cannot produce insulin. Being overweight or obese can impact sleep as we naturally, plays a critical role in physical and mental health. However, it's not only being overweight that has health implications. Being underweight can also carry significant risks. In women, it can lead to menstrual abnormalities and associated health complications with that. In women, it can lead to osteoporosis. So that's a condition characterized by weaker bones, which makes it more susceptible to fracture. But physiologists and dietitians can calculate metabolic rate using equations to determine the basal metabolic rate, that's the minimum energy required to maintain physiological function, so it is dependent upon age, gender and body mass. Resting metabolic rate can still be calculated, and it's similar, but it's measured under different conditions. This is important because knowing the metabolic rate consists professionals to prescribe nutrition and exercise, inventions to manage body composition. So once we know roughly how much energy a person needs to function at rest, we can apply an activity factor to this BMR to determine daily energy requirements, in total, to maintain weight, and use this as a guide to monitor nutritional intake, to manage weight. So in summary, body composition is the compartmentalization of body tissues. Body fat is essential for health, but there is an optimal range and lifestyle choices impact body composition. So overweight and obesity has a range of adverse health risks, and likewise, underweight is also the health risk. Exercise professionals look at the energy requirements and we can calculate those to help us by nutrition and exercise interventions to help people with weight, composition. ANTHROPOMETRY we will build on understanding of body composition and the means available for body composition assessment. By the end of this lecture today, you will understand how to measure and interpret body composition using both field and lab based methods. So assessment methods for many physical tests, including anthropogenic can be divided into field based tests and lab based tests. Generally speaking, field tests are more simple, quicker and cheaper to administer, but can lack the accuracy and sometimes the detail of lab methods. Lab methods, on the other also, are far more accurate, of the more expensive compared to field tests have much tighter testing protocols involving more time, and they make them more challenging to administer to administer. Two groups, we'll go through some of these assessments. Now, with all testing, there are protocols to ensure there are reliability to test. So for height and weight, an example would be weighing someone with shoes off for the first time and then shoes on the next time will result in increasing weight. That's the weight of their shoes, but we could mistakenly conclude that they'd increase weight. So an easy way to avoid confusion with all their testing protocols is to have standardized testing. So with for height, we would remove shoots, we would stand straight and have the feet together. On this last point, think about the difference in height of a couple of centimeters, and the difference between your feet together and your feet wide apart. For body weight, ideally, your point is in minimal clothing, which is not always convenient or comfortable, but something that we should consider for if we're doing some athlete populations, particularly swims or water ball athletes, we're trying to get them with straight from the pool where they have weight here, because that would affect the measurement as well. Body mass index, or BMI, is a common method to non invasively assess body composition in terms of overweight and absent, using just height and weight. So it is based on the concept that individuals with lower body fat will have a lower BMI. However, that's not always accurate in the sense that a heavily muscular athlete can appear overweight or even obese, although they have a metabolically healthy tissue in terms of they have a lot of muscle mass. So here is an example of a classification table which outlines for adults, normal BMI, overweight, obesity and severe obesity would be based upon that relationship of height and weight. Though there's an illustration as discussed in BMI, it's very well researched, and there is really strong relationships between BMI and health complications, such as diabetes, hypertension, coronavisis, heart disease. So colitheasis is the formation of gallstones and hardened deposits within the fluid of the gallbladder, which is small organ under liver, Corona heart disease. So that's CHD. So this BMI chart doesn't even show obesity, which is a BMI over 30 under the risk of higher BMI through the range of normal and overweight as alluded to, BMI is a pretty useful tool for measuring antibiotic at the population level, as for most people, weight increases with percentage of body fat. However, it doesn't directly measure fat mass. Therefore at an individual level, it might not, might not necessarily be a great measure. So for example, if you lose three kilograms of muscle and gain three kilograms of fat to body mass index, let's say very muscley individuals are often considered overweight or obese, and the elderly can have non representative BMI due to age associated muscle atrophy or decreasing height. It's important to know the limitations of tests, as they will influence your interpretation and interventions. This involves another very common method to assess body fat. They are very important to measure. They are reliable and valid. However, they become slightly invasive because it provides some touching but there are a range of sites that can be used to make the testing a little bit more comfortable. It involves measuring the two layers of subcutaneous fat beneath the skin, and it can provide an estimation of some overall fatness. I talked about reliability. It can have a small error. There's small error associated with every test, but the more you practice, and if you're likely credited level one anthropometrist, you've practiced enough that your error is acceptably low. There's a number of different summation sites. You have seven sites, which provides a good overall view of the body, but sometimes it might only be three or four sites, and sometimes there's an site model as well. We'll be practicing involved in the lab. Whilst it appears a fairly straightforward practice, it is important to practice to get a feel of, first of all, to get an accurate landmark, because there are specific sites that we take a measure. Then also to get a feel of what an appropriate pinch is. So we don't get sometimes it's easy to pinch the muscle inside the sample, which gives it a bigger ring in a lower ring. And if all measures are always taken on the right side of the body, where they can, ideally, we carefully measure and mark the site with a permanent marker. I grabbed this info between the thumb, index finger, just to get a slight fold. We replace the calipers just below that pinch, hold for two seconds and then release. And we do multiple measures at the same site to get valid readings. Some of the sites that we take would be the medzilla, the abdominal, the thigh, triceps and biceps, and it's also subscapular, suprailiac, medial calf, and suppress Mala so there are several methods by the number of different sites, whether it's 34678, and each different summation has a conversion to body fat percentage. So it depends on the number of access sites you have. Some can be uncomfortable for some people. So then you have different samples that you can use to know that the formulas give you body density, but you need to use the serum equation to convert percent with a series a published researcher from the 60s, and it's not the Apple program on your phone. Here are some other methods that you can use to value to test my body fat. So based on the clients that you work with or the sporting organization, they may have a different protocol. So it's important that you're familiar with one specific requirements, and also important that you keep using the same protocol. You cannot compare a three site to a seven site. You compare the three side to three side, or a seven side to seven side. As far as assessments go, gith measurement is about as basic as it can get. However, the power and the surface of the test, it's easy to learn, it's easy to administer. It inexpensive, and the value of information and the relationships to health, it's actually a really good test. As well as the waste, there's also a full body assessment, which will involve measuring other areas. So it's really important to practice these you're entering someone else's physical zone. You're touching. It's a minimal touch, but you're still touching. So whilst trying to accurately place a tape and read small writings, it can be quite challenging, so it's really important to practice these you can also measure a mid thigh, thigh, forearm and cut. I stated earlier there was a waist to hip ratio, and given the low cost of the test, information value is incredibly high. Higher scores of waste relative to keep circumference indicates higher abdominal fat, which is an increased risk of cardiovascular disease, and that's the android or apple shape that we talked about in the previous lecture. There are optimal ranges, and there's risk related to waste to heat ratios. So this is some really important information for such a non invasive and simple test, but also laboratory tests which become more complicated and provide more detailed information. So these include the scans hydrostatic weight, air displacement and biological impedance, which we'll go through now. So a dual energy X ray, or DEXA, is a low radiation X ray scan of the entire body, which can estimate body fat and bone density. It has mass less radiation than an x ray, and it's able to identify fat and bone and it can actually provide excellent detail on fat mass and really important information on bone density. So that bone density so that bone density information is quite important for specific populations. It could also be done in conjunction with a more frequently performed field test. There's a comparison, because it's expensive for them and requires professional expertise. For example, The Sporting Club might do one test in their preseason as a really detailed assessment. At the same time, they'll do skin folds, and they'll use that skin fold comparison to Dexter skin to track their athletes with multiple skin fold assessments throughout the season. Hydrostatic weighing. This is where the subject is weighed on land, and then when they land fully submerged in water, and relies on the difference between underwater and out of water weights and the density of the body and water displacement. This is not as popular due to the non population scans, due to the inconvenience of being weighed underwater, and it requires the specialized equipment that subject must also exhale or their air and then remain underwater, which makes it a somewhat difficult process. There's also air displacement, which was used to overcome the need to submit some of the water, and also calculated based upon weight and air displacement. But again, it's less popular test because it's time consuming and expensive. And finally, we have bio electrical impedance analysis. Now, whilst you could argue that this is a field measure rather than a lab measure, it does require a specialized piece of equipment. So that's what's included here. This is where a low level current is passed through the body to estimate the body fat percentage, given that lean tissue contains more water than fat tissue, the level of resistance to the current, indicating that lean versus fatness. This is certainly much cheaper than other lab based methods that's not as reliable and only provides a general measure of body composition. It could also be influenced by hydration status and even moisture on hair and clothes. So whilst we understand we try standardize all our tests, we can see that there's more errors can be introduced into a b by a test. So in summary, body composition can be assessed by field or lab tests. The field tests are cheaper, they're quicker and but they're less accurate than lab the lab much more accurate, much more detailed, but they can be expensive. They're also prohibitive for large groups, because the time requirements for the streets protocols, BMI home weight only, and that has a great relationship to health risk. So does he have to weight ratio, girth OS detects remains the gold standard for body composition. It is a little more expensive regarding specialized equipment and harder to get body composition. Assessment for exercise and sports science professionals is a really important tool in the assessment toolbox, and this will form part of our labs where we get a lot of hands on experience, learning how to do girths and skin vaults, learning to I'm encourage you to be involved in the lab as much as possible, to practice these skills. Thank you for listening to today's lecture if you have any questions, please ask your tutors or send His names. Thanks
Updated 60d ago
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1. Functions of Muscles: • Movement: Muscles contract to produce movement in the body, such as walking, running, or even facial expressions. • Posture and Stability: Muscles help maintain posture and stabilize joints, preventing falls or loss of balance. • Heat Production: Muscle contractions generate heat, which is vital for maintaining body temperature. • Protection of Internal Organs: Muscles, particularly in the abdominal region, protect internal organs from injury. • Circulation of Blood and Lymph: Cardiac and smooth muscles play roles in circulating blood and lymph throughout the body. 2. Characteristics of Muscles: • Excitability (Responsiveness): Muscles can respond to stimuli (like nerve signals). • Contractility: Muscles can contract or shorten when stimulated. • Extensibility: Muscles can be stretched without damage. • Elasticity: Muscles can return to their original shape after being stretched or contracted. 3. Locations of Smooth, Cardiac, and Skeletal Muscle: • Smooth Muscle: Found in walls of internal organs (e.g., stomach, intestines, blood vessels). • Cardiac Muscle: Found only in the heart. • Skeletal Muscle: Attached to bones and responsible for voluntary movements. 4. Events of Skeletal Muscle Contraction: 1. Nerve Impulse: A signal is sent from a motor neuron to the muscle. 2. Release of Acetylcholine: The neurotransmitter acetylcholine is released into the neuromuscular junction. 3. Muscle Fiber Activation: Acetylcholine stimulates muscle fibers, causing an action potential. 4. Calcium Release: The action potential triggers the release of calcium ions from the sarcoplasmic reticulum. 5. Cross-Bridge Formation: Calcium binds to troponin, moving tropomyosin, which allows myosin heads to attach to actin. 6. Power Stroke: Myosin heads pull actin filaments inward, causing the muscle to contract. 7. Relaxation: ATP breaks the cross-bridge, and the muscle relaxes when calcium is pumped back into the sarcoplasmic reticulum. 5. Isometric vs. Isotonic Contractions: • Isometric Contraction: The muscle generates tension without changing its length (e.g., holding a weight in a fixed position). • Isotonic Contraction: The muscle changes length while generating tension (e.g., lifting a weight). 6. Primary Functions of the Skeletal System: • Support: Provides structural support for the body. • Protection: Shields vital organs (e.g., brain, heart, lungs). • Movement: Works with muscles to allow movement. • Mineral Storage: Stores minerals like calcium and phosphorus. • Blood Cell Production: Bone marrow produces blood cells. • Energy Storage: Fat is stored in bone cavities. 7. Parts of a Long Bone: • Diaphysis: The shaft of the bone. • Epiphysis: The ends of the bone. • Metaphysis: Region between the diaphysis and epiphysis. • Medullary Cavity: Hollow cavity inside the diaphysis, containing bone marrow. • Periosteum: Outer membrane covering the bone. • Endosteum: Inner lining of the medullary cavity. 8. Inner and Outer Connective Tissue Linings of a Bone: • Outer: Periosteum. • Inner: Endosteum. 9. Structure of a Flat Bone: • Compact Bone: Dense bone found on the outside. • Spongy Bone: Lighter, less dense bone found inside, filled with red or yellow marrow. • No medullary cavity (unlike long bones). 10. Parts of the Osteon: • Central Canal (Haversian Canal): Contains blood vessels and nerves. • Lamellae: Concentric layers of bone matrix surrounding the central canal. • Lacunae: Small spaces containing osteocytes (bone cells). • Canaliculi: Small channels that connect lacunae and allow for nutrient exchange. 11. How Calcitonin, Calcitriol, and PTH Affect Blood Calcium: • Calcitonin: Lowers blood calcium levels by inhibiting osteoclast activity (bone resorption). • Calcitriol: Increases blood calcium by promoting calcium absorption in the intestines and bone resorption. • PTH (Parathyroid Hormone): Raises blood calcium by stimulating osteoclasts to break down bone and release calcium. 12. Two Forms of Ossification: • Intramembranous Ossification: Bone develops directly from mesenchymal tissue (e.g., flat bones of the skull). • Endochondral Ossification: Bone replaces a cartilage model (e.g., long bones). 13. Difference Between Appositional and Interstitial Growth: • Appositional Growth: Increase in bone diameter (growth at the surface). • Interstitial Growth: Increase in bone length (growth from within). 14. Different Joint Types: • Fibrous Joints: Connected by fibrous tissue (e.g., sutures of the skull). • Cartilaginous Joints: Connected by cartilage (e.g., intervertebral discs). • Synovial Joints: Have a fluid-filled joint cavity (e.g., knee, elbow). 15. Components of a Synovial Joint: • Articular Cartilage: Covers the ends of bones. • Synovial Membrane: Lines the joint capsule and produces synovial fluid. • Joint Capsule: Surrounds the joint, providing stability. • Ligaments: Connect bones to other bones. • Synovial Fluid: Lubricates the joint. 16. Hinge Joint Location: • Found in the elbow and knee. 17. Pivot Joint Location: • Found between the first and second cervical vertebrae (atlantoaxial joint). 18. Difference Between a Tendon and a Ligament: • Tendon: Connects muscle to bone. • Ligament: Connects bone to bone. 19. What is a Bursa? • A fluid-filled sac that reduces friction and cushions pressure points between the skin and bones or muscles and bones. 20. Three Types of Arthritis: • Osteoarthritis: Degeneration of joint cartilage and underlying bone, often due to wear and tear. • Rheumatoid Arthritis: Autoimmune disease causing inflammation in joints. • Gout: Caused by the accumulation of uric acid crystals in the joints. 21. Strain vs. Sprain: • A strain is damage to a muscle or tendon, whereas a sprain is damage to a ligament
Updated 63d ago
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BASIC STRUCTURE AND PROMINENT FUNCTIONS OF VERTEBRATE INTEGUMENT INTRODUCTION The integument or the outer cover of the body is commonly referred to as the skin. Together with its derivatives it makes up the integumentary system. It is continuous with the mucous membrane lining the mouth, eyelids, nostrils, rectum and the openings of the urino-genital ducts. The skin functions primarily to cover and protect the tissues lying beneath it. In other words, it forms the external protective covering of an animal. Forms interface between organism and external environment. Part that the predator sees first, and which offers the first line of defense. Abundantly supplied with sensory nerve endings, which are affected by environmental stimuli and play an important role in communication. General metabolism of the body, temperature regulation and water loss. Character of the skin and its derivatives shows variation in different regions of the body, in different individuals, in the same individual as age advances and in different groups of vertebrates. The type of environment whether aquatic or terrestrial is of importance in connection with these variations. The evolution of vertebrate integument is correlated with the transition of vertebrates from an aquatic to a terrestrial environment. Nevertheless, basic similarities exist in the integument of all vertebrates. INTEGUMENT PROPER In Annelids, Arthropods, integument consists of single layer of cells, the EPIDERMIS, together with an outer non-cellular CUTICLE, secreted by the cells. Annelids have a body covered with an external thin collagenous cuticle (never shed or molted). In Arthropods, the chitinous and rigid cuticle makes up the exoskeleton. Periodic shedding of this cuticle is termed Ecdysis. THE VERTEBRATE SKIN DIFFERS FROM INVERTEBRATE SKIN TWO LAYERS – Outer epidermis derived from ectoderm Inner dermis or corium of mesodermal origin. The relative amount of the two layers varies with the environment. EPIDERMIS – the epidermis is made of stratified epithelium (several layers of columnar epithelium cells). These cells are held together tightly by minute intercellular bridges found on the surface of cells. The innermost layer is stratum Malpighii or stratum germinativum placed over a thin basement membrane. These cells divide constantly to produce new cells. Move upwards, tend to become flattened, protoplasm becomes horny (keratinisation). In fishes and amphibians, this keratinised layer forms a cuticle, but in amniotes, it forms stratum corneum, of hard, horny, flat, cornified cells made largely of keratin, which is tough, waterproof and insoluble protein. It affords protection against mechanical injuries, fungal and bacterial attacks and prevents desiccation. In many Tetrapoda, this layer is shed periodically in pieces or all at once. No stratum corneum in cyclostomes and fishes (since they are fully aquatic) here the epidermis has mucous glands, secreting mucus to keep the skin slimy and protects it from bacteria. The epidermis has no blood vessels and is nourished by capillaries in the dermis. The epidermis rests on a thin basement membrane which separates it from the dermis Dermis has an outer loose layer and inner dense layer Made up of dense connective tissue having cells, muscles, blood vessels, lymph vessels, collagen and elastic fibres, and nerves. Amphibians and reptiles -collagen fibres at right angles in three planes Birds and mammals, they have an irregular arrangement. Substances pass by diffusion from the dermis to the epidermis. Skin contains pigment, if present in epidermis, it occurs as a diffuse substance or as granules. If in dermis, then in the form of granules in special branching cells called chromatophores. The pigment can either collect as a central ball making the skin lighter or spread out into all the branches making the skin darker, thus, chromatophores bring about colour variations. Chromatophores are of many kinds, Melanophores that contain brown to black pigment Lipophores or xanthophores which contain yellow red fatty pigments Iridocytes or guanophores contain crystals of guanine which reflect light. Under dermis, the skin has subcutaneous loose areolar tissue which separates the skin from the underlying muscles, it may contain fat and muscles, especially in mammals. Integument of Anamnia shows a decrease in thickness and also a decrease in the degree of ossification. These are of advantage in allowing greater mobility and in amphibians, they permit respiration by the skin. But in Amniota, the skin becomes progressively thicker to prevent loss of water and to retain body heat. STRUCTURE OF INTEGUMENT IN CYCLOSTOMATA Epidermis is multi-layered (stratified) but has no keratin. It has three types of unicellular gland cells: mucus glands (secrete mucus), club cells (scab-forming cells) and granular cells (unknown function). Below epidermis is the cutis formed of collagen and elastin fibres. Star- shaped pigment cells are also present in the cutis. STRUCTURE OF INTEGUMENT IN PISCES The epidermis has several layers of simple and thin cells, but there is no dead stratum corneum. The outermost cells are nucleated and living. The stratum Malpighii replenishes the outer layers of cells which have some keratin. Unicellular goblet or mucous gland cells are found in the epidermis, as in all aquatic animals. The mucous makes the skin slimy reducing friction between the body surface and water, protects the skin from bacteria and fungi and assists in the control of osmosis. Multicellular epidermal glands like poison glands and light producing organs may also be found. The epidermis rests on a delicate basement membrane. The dermis contains connective tissue, smooth muscles, blood vessels, nerves, lymph vessels and collagen fibres. The connective tissue fibres are generally not arranged at right angles but run parallel to the surface. Scales are embedded in the dermis and projected above the epidermal surface. The colours of fishes are due to chromatophores and iridocytes. STRUCTURE OF INTEGUMENT IN AMPHIBIA: The epidermis has several layers of cells, six to eight cells in thickness and is divisible into three layers: stratum corneum, stratum germinativum and a basal portion in contact with the basement membrane. The outermost layer is a stratum corneum, made of flattened, highly keratinised cells. Such a dead layer appears first in amphibians and is best formed in those which spend a considerable time on land. The stratum corneum is an adaptation to terrestrial life (protects body and prevents excessive loss of moisture). In ecdysis, stratum corneum is cast off in fragments or as a whole in some. (moulting / desquamation i.e., removal of unicellular sheet of stratum corneum). The dermis is relatively thin in amphibians, it is made of two layers - upper loose stratum spongiosum and a lower dense and compact stratum compactum. Connective tissue fibres run both vertically and horizontally. Blood vessels, lymph spaces, glands and nerves are abundant in the stratum spongiosum. There are two kinds of glands, multicellular mucous glands and poison glands in the dermis, but they are derivatives of the epidermis. Mucous gland produces mucus (slimy protective covering, helps in respiration). Amphibian skin is an important organ of respiration. Poison glands produce a mild but unpleasant poison which is protective. In the upper part of the dermis are chromatophores. (melanophores and lipophores) Ability of the skin for changing colour to blend with the environment is well developed. INTEGUMENT IN REPTILIA. The integument is thick and dry, it prevents any loss of water, it has almost no glands. The only glands present are scent glands for sexual activity. The epidermis has a well-developed stratum corneum well adapted to terrestrial life. The horny scales of reptiles are derived from this layer. Ecdysis is necessary to remove dead outer layers, hence scales are shed periodically in fragments or cast in a single slough as in snakes and some lizards Scales often form spines or crests. Below the epidermal scales are dermal bony plates or osteoderms in tortoises, crocodiles and some lizards (Heloderma). The dermis is thick and has an upper layer and a lower layer, upper layer has abundance of chromatophores in snakes and lizards. Lower layer has bundles of connective tissue in which collagen fibres lie at right angles. Leather of high commercial value can be prepared from the skin of many reptiles like lizards, snakes and crocodiles. Many lizards and snakes have elaborate colour patterns, they may be for concealment or as warning colours. There is marked colour change in certain lizards such as chameleon, the colour may change with the environment for concealment or it may change in courtship or threat. The ability of chameleons and some other animals to change colour is known as metachrosis. (metachromatism) In Calotes, chromatophores are controlled by the posterior lobe of pituitary whereas in chameleons they are controlled by the Autonomic Nervous System. INTEGUMENT IN BIRDS Thin, loose, dry and devoid of glands. There is only a uropygial gland at the base of the tail, its oil is used for preening (to clean and tidy its feathers with its beak) and waterproofing the feathers (aquatic birds) Epidermis is delicate except on shanks and feet where it is thick and forms epidermal scales. The rest of the body has a protective covering of epidermal feathers. The keratin producing powers of the epidermis are devoted to producing feathers and scales. The dermis is thin and has interlacing connective tissue fibres, abundant muscle fibres for moving feathers, blood vessels and nerves. The dermis has an upper and lower compact layer, between which is a vascular layer, the dermis also contains fat cells. The skin has no chromatophores. Pigment is found only in feathers and scales. Colour patterns in birds are vivid (concealment, recognition and sexual stimulation) Colours are produced partly by pigments and partly by reflection and refraction from the surface of the feathers. INTEGUMENT IN MAMMALS Skin is elastic and waterproof, much thicker than in other animals, especially the dermis is very thick and is used in making leather. Epidermis is thickest in mammals. Outer stratum corneum containing keratin, cells not dead as believed before. Below this is stratum lucidum (barrier layer), chemical called eleidin Below this stratum granulosum, darkly staining granules of keratohyalin Below this is stratum spinosum whose cells are held together by spiny intercellular bridges. Lastly stratum germinativum which rests on a basement membrane Dermis is best developed in mammals. Upper layer is papillary layer made up of elastic and collagen fibres with capillaries in-between, thrown into folds called dermal papillae, especially in areas of friction Greater lower part of dermis is reticular layer, having elastic and collagen fibres. In both layers there are blood vessels, nerves smooth muscles, certain glands tactile corpuscles and connective tissue fibres in all directions. Below dermis the subcutaneous tissue contains a layer of fat cells forming adipose tissue In the lowest layer of epidermis there are pigment granules, no pigment bearing chromatophores in mammaIs (in man, branching dendritic cells or melanoblasts) FUNCTIONS OF THE INTEGUMENT ▪ PROTECTION ▪ TEMPERATURE CONTROL ▪ FOOD STORAGE ▪ SECRETION ▪ EXCRETION ▪ SENSATION ▪ RESPIRATION ▪ LOCOMOTION ▪ DERMAL ENDOSKELETON ▪ SEXUAL SELECTION 1. Protection: The integument forms a covering of the body and is protective. It protects the body against entry of foreign bodies and against mechanical injuries. It protects the tissues against excessive loss of moisture, this is very important because both aquatic and terrestrial animals are dependent upon water in their bodies for various metabolic activities. The integument forms protective derivatives, such as scales, bony plates, layer of fat, feathers and hair which reduce the effect of injurious contacts. In some animals the skin shows protective colouration which makes the animals resemble their environment, thus, making them almost invisible to their enemies. Poison glands of toads, slippery skin of aquatic animals and an armour of spines of some mammals are protective devices of the integument. The skin forms a covering which prevents the passage of water and solutes in one of the following ways: (a) By formation of cuticle in Protochordata and embryos of fishes and amphibians, (b) By secreting a coat of mucus in fishes and aquatic amphibians, and (c) By formation of keratin layers in the epidermis of tetrapoda. Keratin is formed from the cytoplasm of degenerating cells of the epidermis which finally form a layer of horny stratum corneum. 2. Temperature Control: Heat is produced constantly by oxidation of food stuffs in tissues. This heat is distributed evenly by the circulating blood. The body heat is lost constantly with expired breath, with faeces and urine, and from the surface of the skin. The integument regulates heat and maintains a constant temperature in endothermal animals. In birds the heat is regulated by adjustment of feathers which retain a warm blanket of air, when feathers are held close to the body, they remove warm air and body cooled, when feathers are fluffed out, they keep the warm air enclosed. In mammals, constant evaporation of sweat regulates the body heat. In cold weather contraction of skin’s blood capillaries reduces the loss of body heat. In some animals, fat in the skin prevents loss of heat because it is a non-conductor of heat. 3. Food Storage: The skin stores fat in its layers as reserve food material which is used for nourishment in times of need. In whales and seals the fat of the skin forms a thick layer, called blubber which is not only reserve food but also maintains the body temperature. 4. Secretion: The skin acts as an organ of secretion. Glands of the skin are secretory. In aquatic forms there are secretory mucous glands whose secretions keep the skin moist and slippery. In mammals, sebaceous glands secrete oil which lubricates the skin and hairs. Mammary glands produce milk for nourishment of the young. In birds uropygial glands secrete oil for preening the feathers. Odours of scent glands attract the opposite sex. Lacrymal glands’ secretion wash the conjunctiva of eyeball in mammals. Ear wax (cerumen) secreted by the glands of auditory meatus greases the eardrums and avoids insects to enter the canal. 5. Excretion: The integument acts as an organ of excretion. Shedding of the corneal layer during ecdysis removes some waste substances. In mammals metabolic waste (salts, urea and water) is removed from the blood by means of sweat. Chloride secreting cells are found in gills of marine fishes. 6. Sensation: The skin is an important sense organ because it has various kinds of tactile cells and corpuscles which are sensory to touch, temperature changes, heat, cold, pressure and pain. 7. Respiration: In amphibians, the moist skin acts as an organ of respiration, in frogs the respiratory function of the skin is greater than that of the lungs. 8. Locomotion: Derivatives of the integument bring about locomotion in some animals, such as the fins of fishes aid in locomotion in water, the web of skin in the feet of frogs and aquatic birds aid in swimming, feathers of the wings and tail of birds are used for flying, and extensions of the integument forming “wings” of flying lizards, extinct pterodactyls, flying squirrels and bats. 9. Dermal Endoskeleton: The skin contributes to the endoskeleton. It forms the dermal bones of vertebrates and also forms parts of the teeth. Endoskeleton of head protects the brain and sense organs. In the body it protects the soft, tender viscera. 10. Sexual Selection: The skin acts as an organ of sexual selection. It provides the feathers of birds which often have brilliant colours which are for sexual attraction. Some integumentary glands of mammals produce odours far attracting the opposite sex. Antlers of male deer distinguish it from female. Besides the above functions, mammalian skin synthesizes the vitamin D with the help of Sebum of sebaceous glands. Brood pouches beneath skin in some fishes and amphibians protect unhatched eggs. Nasal glands of tetrapods, keep the nostrils free of dirt and water. Skin also has the power of absorption of oils, ointments, etc
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You place a RBC (0.9%) into a 5% sugar solution. Which statement below is false? The RBC is hypotonic to the 5% solution Which is an example of a sensor in a negative homeostatic feedback loop? Chemoreceptor in carotid body For membrane fluidity experiment, the part of the experiment that actually validated that the membrane was fluid was: The labeled antibodies of the human and mouse intermixing An example of primary active transport would be a protein requiring ATP to transport sodium ions across the plasma membrane. True If a red blood cell is put in a solution and it hemolyzes, then the solution is considered to be: Hypotonic If your body temperature goes too high you can denature enzymes in your body. True What does an integrator do in a homeostatic pathway? Measures the signal coming in to a set point and send a signal out to the body Which of the following represents stages of the cell division (mitosis) in the proper sequence? Prophase, metaphase, anaphase, telophase Which is not true for proteins? They are comprised of mostly cellulose What would be a disturbance for blood glucose homeostasis (normal blood glucose set point = 77mg/dL)? A permanent decrease in insulin production from the Islets of Langerhans Dr. Bio measures your total cholesterol and he reports back to you that your level is 300 mg/ 100 ml of plasma. You do what? Eat more oatmeal and flax to increase your HDL level. How do you make an unsaturated fatty acid? Perform a dehydration synthesis reaction on a saturated fatty acid Which is false for antioxidants? They speed up reactions in your body Which molecules do not dissolve in water? Non-polar Which molecule requires a transport protein to get through the plasma membrane (either channel or carrier protein)? Two of the answers are correct Interphase is considered to be part of normal cell division (mitosis). False What is the function of ATP? All of the answers are correct What are the three kinds of lipids? Triglycerides, phospholipids, and steroids When glycerol combines with 3 fatty acids to form a triglyceride (fat), which of the following chemical reactions has occurred? Dehydration Synthesis How can you alter a protein’s shape? More than one answer is correct If a red blood cell is put into a solution and it maintains its shape, then the solution is considered to be: Isotonic Which molecule requires some type of transport protein to get through the plasma membrane? Sodium Ion Cofactors are molecules that activate enzymes. Which is not a cofactor? Mercury The nitrogenous bases found in DNA have complementary paring. Which pair is correct? C-G Which is not true for meiosis? Results in a gamete that is 2N In the diagram below the two solutions are separated by a semi permeable membrane. In which direction will net movement of water occur? From side A to side B Which is not a component of a DNA molecule: Ribose Sugar Phospholipids are similar to fatty acids except for? Phospholipids have a phosphate group Which is not true for cells? They allow diffusion of all molecules If you combine a molecule of glucose and fructose, which statement is true? You have formed sucrose Which is true for enzymes? Activity will increase until the enzyme becomes saturated What method would you use to get glucose into a cell along/down it’s concentration gradient (from high to low)? Facilitated Diffusion Which is not considered an integrator in a negative homeostatic feedback loop? Pancreas Which phase of the cell cycle is where cytokinesis takes place? Telophase What vitamin do we produce by sitting in the sun; it aids in calcium absorption from the small intestine? Vitamin D Why is it important to think about ion dissociation in the body? All the above In what order do you use macromolecules for fuel? Carbohydrates, lipids, proteins Which is false for cholesterol? It can dissolve in water/blood You place a RBC (0.9%) into a 0.5% sugar solution. Which statement below is false? The RBC is hypertonic to the 0.5% solution Which is not a membrane protein function? Protein synthesis Ingesting (eating) excess hydrophilic vitamins, such as vitamin C, results in excess vitamin C being stored in your tissues. False Diffusion is: The movement of molecules from an area of high molecular concentration to an area of low molecular concentration across a selectively-permeable membrane The hormone responsible for glucose uptake/removal from the blood is: Insulin What method would you use to get sodium ions into a cell against sodium’s concentration gradient (from low to high concentration)? Active Transport Which phase of the cell cycle is where the cell is functioning normally or doing its job? Interphase Evidence for mitochondria once being bacteria that our cells engulfed is: It has it’s own DNA Ionic molecules (ie NA+, K+) can diffuse straight through the plasma membrane. True What is the difference between cis and trans fatty acids? Cis fatty acids have hydrogens on the same side of the carbon double bond and trans fatty acids do not Cofactors are molecules that activate enzymes. Where do we get cofactors from? Vitamins found in fruits and vegetables RNA has what nitrogenous base in place of thymine? Uracil Large polar molecules (ie glucose) can diffuse straight through the plasma membrane? False Which lipoprotein is comprised of more protein and less cholesterol so it scavenges for cholesterol in the blood? High density lipoprotein A normal human being has 46 chromosomes (23 pairs/2N/diploid) in each somatic cell (body cell). True The three main compounds digested by the digestive system are? Fats, carbohydrates, and proteins Meiosis is the process in which our sex cells go from 46 chromosomes to 23 single chromosomes. True The effector in any negative feedback loop is usually: An organ/tissue If a red blood cell is put into a solution and it crenates (shrinks), then the solution is considered to be: Hypertonic Which statement is false for glycogen? It is a disaccharide Enzymes aid in digestion by? Lowering the energy required to break food apart Nonpolar molecules (ie CO2) can diffuse straight through the plasma membrane
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