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Sarcomere
unit from Z-line to Z-line
Z-line
sarcomere boundary where actin anchors
I band
thin filaments only (actin)
A band
entire length of thick filaments (myosin)
H zone
myosin only no overlap
M line
center anchors myosin
Actin
thin filament protein
Myosin
thick filament motor protein
Tropomyosin
covers actin binding sites
Troponin
binds Ca²⁺ to move tropomyosin
Titin
elastic protein anchors myosin to Z-line
Sliding filament theory
filaments slide → sarcomere shortens
ACh
acetylcholine neurotransmitter at NMJ
SR
sarcoplasmic reticulum stores and releases Ca²⁺
Ca²⁺
binds troponin to start contraction
ATP
energy for cross-bridge cycling and relaxation
Slow oxidative fiber
red endurance fiber resists fatigue
Fast glycolytic fiber
white fiber for quick power