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How is obesity measured?
BMI
abdominal obesity
stomach weight, increases as BMI goes up
Visceral fat
Deep fat near organs
Male-pattern obesity
apple shape, predominantly around stomach
Female-pattern obesity
pear shape, store fat in upper arms and hips
What are some problems with BMI?
does not account for muscle mass which weights more
Why does muscle mass help us maintain weight?
takes more calories for muscle to maintain itself than fat
NHANES
National health and nutrition examination survey
Why are obesity levels rising?
Food change (shift towards fast food, UPF and sugary drinks, more available and cheaper), increased cost of living, sedentary lifestyle (technology, increased screen time)
What are some consequences of obesity?
cardiovascular disease, hypertension, T2D, asthma
Adipocytes
collapsible body cells that store fat
Biological basis of weight regulation
fat cells expand and contract but when they reach their maximum storage of fat they divide
Fat-cell hyperplasia
dramatic increase in number of fat cells from normal, very hard to lose them at this point
Hazards of obesity
hyperinsulemia, metabolic syndrome
Etiology of obesity
biology, psychosocial factors, behavioral choices
Hereditary Obesity
contribute approximately 50%, 60% of obese people had obese biological parents
Support for heredity
body weight of adopted children correlate more strongly with weights of biological parents
What does genetics influence?
metabolism (basal metabolic rate)
Basal Metabolic Rate
the minimum number of calories your body requires to perform essential life-sustaining functions while at rest
Calorie
Measure of food energy equivalent to the amount of energy needed to raise temperature of one gram of water one degree celsius
Set point hypothesis
body has a sweet spot for weight, you can move beyond this point in either direction but the body tries to protect its settling point. This is adaptive because the body expects long periods hunger and can rely on fat stores but our access to food now is not what the evolutionary system was created for.
ethnicity and gender with obesity
lowest rates with non-hispanic asian, highest in non-hispanic black women and latinx men
which group has the highest prevalance of obesity in the US?
native americans
Food Deserts
geographical areas with little or no access to foods needed to maintain a healthy diet
Substance use disorder
pattern of behavior characterized by impaired control, social impairment, and risky use of a drug
Behavioral Addiction
new category, gambling, gaming
How many deaths does SUD cause?
more than any other preventable health conditions
Drugs and adolescence
prevalence and incidence increase every year from age 10 to 25 then decrease, use before 18 is strong indicator of later abuse
Recognizing and Diagnosis Abuse
the continued use of a substance despite repeated occurrence of significant adverse consequences related to the use of that substance
Tolerance
the more you use something the more you will need to have the same effects, body is changing so it can avoid intoxication
Withdrawal
if stopped cold turkey, the body needs time to readjust as it has been working harder to keep you alive under the influence
Why are opiods the most painful withdrawal?
hijack pain system
how do most people die from opioids?
overdose: go through withdrawal, get clean, use again at same amount as when they stopped, but tolerance is lower, death
Psychoactive Drugs
hallucinogens, stimulants, and depressants
Hallucinogens
psychedelic drugs; marijuana, LSD; sensory changes that are not biologically real
Cannabis
hallucinogenic, depressant, and stimulant effects. At low doses, serene, positive and relaxed feelings. At high doses, paranoia, schizophrenia, heart racing. Effects last 3-6 hours.
Physical and Health risls of cannabis
chronic daily use can lead to long-term psychiatric problems, psychosis, cancer, cognitive slowing, can become dependent
Stimulants
Nicotine, caffeine, cocaine, amphetamines. boost CNS activity, highly rewarding, rapid development of dependence
What is the most powerful stimulant known?
cocaine
Amphetamines
manufactured, tolerance develops quickly (when come down you get very depressed or tired)
Depressants
alcohol, sedatives, opiates. At low doses they are calming. At high doses they affect our ability to process information and our motor skills. Highly addicitve and death often occurs from slowed breathing or aspirating
Biomedical model of SUD
genetics, adopted children are more susceptible to dependency if one or both biological parents were. higher coincidince with idetical twins than fraternal twins.
Withdrawal-reflief hypothesis
the idea that drug use serves to restore abnormally low levels of key neurotransmitters, people with lower levels of these (depression, anxiety, low self-esteem) feel even better than their counterparts on the same dosage
Reward Model
Mesolimbic dopamine system
Mesolimbic dopamine system
composed of the VTA (ventral tegumental area) and NAc (nucleus accumbens). This VTA-NAc circuit is a key detector of a rewarding stimulus
Incentive-Sensitation Theory
Two-stage theory, use it to start feeling good but then become conditioned
Social Learning Models
substance use shaped by environment with parents being a strong indicator,
Social Control Theory
kids that have alot of unmonitored free time are more likely to use whereas their counterparts in alot of activities are less
Peer Cluster Theory
who you hang out with affects your usage patterns
Physical Effects of Alcohol
affects all parts of the body, major effects on hippocampus (memory)
Korsakoffs Syndrome
alcohol use dementia, inability to store new memories due to usage, deficiency of thiamin (vitamin b) and is completely reversible
Other damaging effects of alcohol
cardiovascular disease (biggest risk), liver disease, cancer, digestive issues, immune supression
Treatment Plan for Obesity
Lifestyle interventions (nutrition, exercise, maintenance, coping skills training)
Nutrition (what doesn’t work, treatment plan for obesity)
diets don’t work because people are not accurate at estimating calorie needs, hard to stick with and poor knowledge of food