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Vocabulary flashcards covering key terms from the lecture notes.
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Chromosome
Structure within a cell that contains genetic material; in eukaryotes the DNA–protein complex is organized as chromatin.
Gene
Unit of heredity located on a chromosome that governs a trait.
DNA
Deoxyribonucleic acid; the genetic material that makes up chromosomes.
Chromatin
DNA–protein complex in eukaryotes that forms the material of chromosomes.
Non-coding RNA
RNA molecules on chromosomes that do not code for proteins.
Prokaryote
Cell type without a membrane-bound nucleus (e.g., bacteria, archaea).
Eukaryote
Cell type with a membrane-bound nucleus and organelles (protists, fungi, plants, animals).
Nucleoid
Region in a prokaryotic cell where the circular chromosome is located.
Nucleus
Membrane-bound organelle in eukaryotic cells that houses genetic material.
Mitochondrion
Organelle with its own DNA; site of ATP synthesis.
Golgi apparatus
Organelle involved in protein modification and trafficking.
Somatic cell
Body cell (non-gamete) in an organism.
Germ cell
Cell that gives rise to gametes (reproductive cells).
Karyotype
Organized representation of the chromosomes of a cell, usually ordered by size.
Diploid
Two complete sets of chromosomes (2n) in a cell.
Haploid
One set of chromosomes (n); typical of gametes.
Homologous chromosomes
Pair of chromosomes similar in size and gene order; carry the same genes, possibly different alleles.
Locus
Physical location of a gene on a chromosome.
Allele
Variant form of a gene.
Genotype
Genetic constitution for a gene; e.g., AA, Bb, cc.
Homozygous
Having two identical alleles for a gene.
Heterozygous
Having two different alleles for a gene.
Chromatid
One of the two identical copies of a replicated chromosome.
Dyad
Pair of sister chromatids joined at the centromere.
Sister chromatids
Two identical copies of a chromosome held together at the centromere.
Centromere
Constricted region where sister chromatids are held; site for kinetochore attachment.
Kinetochore
Protein structure at the centromere that attaches to spindle microtubules.
Centrosome
Organizes the spindle apparatus; contains two centrioles in animal cells.
Centriole
Cylindrical cell structure within the centrosome involved in organizing spindle fibers.
Spindle apparatus
Structure that separates chromosomes during cell division.
Aster microtubules
Radial microtubules around centrosomes aiding spindle positioning.
Polar microtubules
Microtubules that push the poles apart during division.
Kinetochore microtubules
Attach to kinetochores on chromosomes to move them during division.
Interphase
Cell-cycle stage (G1, S, G2) when the cell grows and DNA is replicated.
G1 phase
First gap phase; cell grows and prepares for DNA replication.
S phase
DNA synthesis phase; chromosomes are replicated.
G2 phase
Second gap phase; cell prepares for mitosis.
Mitosis
Nuclear division that distributes replicated chromosomes into two daughter nuclei.
Prophase
Chromosomes condense; nuclear envelope breaks down; spindle forms.
Prometaphase
Spindle fibers attach to kinetochores; chromosomes begin moving toward center.
Metaphase
Chromosomes align at the metaphase plate; attached to opposite poles.
Anaphase
Sister chromatids separate and move to opposite poles.
Telophase
Nuclei reform around separated chromosomes; chromosomes de-condense.
Cytokinesis
Division of the cytoplasm to form two separate daughter cells.
Cleavage furrow
Indentation that forms in animal cells during cytokinesis.
Cell plate
Precursor to a separating cell wall in plant cytokinesis.
Meiosis
Reduction division producing haploid gametes; two divisions (Meiosis I and II).
Meiosis I
First meiotic division; homologous chromosomes pair and cross over; reduces chromosome number.
Meiosis II
Second meiotic division; sister chromatids separate, producing four haploid cells.
Leptotene
Stage of Prophase I where chromosomes condense.
Zygotene
Stage of Prophase I where synapsis begins between homologs.
Pachytene
Stage of Prophase I where crossing over occurs and bivalents form.
Diplotene
Stage of Prophase I where synaptonemal complex dissociates.
Diakinesis
End of Prophase I; chromosomes condense further preparing for meiosis I.
Bivalent/Tetrad
Pair of homologous chromosomes during meiosis I (each with two sister chromatids).
Crossing over
Exchange of genetic material between homologous chromosomes during meiosis I.
Spermatogenesis
Production of sperm in the male reproductive system.
Spermatogonia
Diploid germ cells that divide to form primary spermatocytes.
Primary spermatocyte
Diploid cell that undergoes meiosis I.
Secondary spermatocyte
Haploid product of meiosis I that undergoes meiosis II.
Spermatids
Haploid cells that differentiate into sperm.
Sperm
Mature male gamete with haploid nucleus.
Oogenesis
Production of egg cells in the female reproductive system.
Oogonia
Diploid germ cells in ovaries that produce primary oocytes.
Primary oocyte
Diploid cell that begins meiosis I and is arrested in prophase I until puberty.
Secondary oocyte
Large haploid cell produced after meiosis I; arrests until fertilization.
Polar body
Small haploid cell produced during oogenesis that typically degenerates.
Double fertilization
In flowering plants, one sperm fertilizes the egg and another fertilizes the central cell to form endosperm.
Endosperm
Triploid tissue that nourishes the developing embryo in flowering plants.
Gametophyte
Haploid generation of plants that produces gametes by mitosis.
Sporophyte
Diploid generation of plants that produces spores by meiosis.
Spores
Haploid cells produced by meiosis in the sporophyte that develop into gametophytes.
Pollination
Transfer of pollen to the stigma; required for fertilization in plants.
Fertilization
Fusion of gametes to form a zygote; in plants, often involves double fertilization.
X-linked gene
Gene located on the X chromosome.
X-linked trait
Trait determined by an allele on the X chromosome; often shows sex-linked patterns.
Mendel’s laws and chromosomes
Mendel’s law of segregation and independent assortment explained by chromosome behavior during meiosis.
X-Y system
Males are heterogametic (XY) and females are homogametic (XX) in mammals.
X0 system
Males have one X and no Y; sex determined by X/A ratio in some insects.
Z-W system
Sex determination in birds/fish; males are ZZ and females are ZW.
Haplodiploid
Sex determination where males are haploid (from unfertilized eggs) and females are diploid.
Morgan’s experiment
Thomas Hunt Morgan’s Drosophila experiments showing X-linked inheritance with white-eyed mutation.
Punnett square
Diagram used to predict offspring genotypes from parental genotypes.
Karyotype (size order)
Arrangement of chromosomes usually from largest to smallest.