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THE PATIENT ADDS TAP WATER TO THE URINE CONTAINER BECAUSE HE/SHE FORGETS TO SAVE ONE OF THE URINE SAMPLES
Which of the following conditions is most likely to cause a falsely high creatinine clearance result
ORTHO-TOLUIDINE (DUBOWSKI)
The only chemical method still used widely and is based on the condensation of aldosaccharides such as glucose with an aromatic amine and glacial acetic acid
ABELL KENDALL
Three step method for cholesterol determination
REMOVE PERSONS FROM IMMEDIATE DANGER
What is the first course of action to do if a fire occurs in the laboratory
BONE DISEASE
Normal serum GGT level with an elevated serum ALP is suggestive of
ACUTE CIRRHOSIS
A disorder that is generally characterized by a normal alpha 1 globulin level and a decreased alpha 2 globulin
BRIDGING EFFECT BETWEEN THE BETA AND GAMMA GLOBULIN FRACTIONS
In cirrhosis, a predominant characteristic observed on an electrophoretic serum protein pattern is a(n)
GLYCOGEN
In what form is glucose stored in the muscle and liver
HEPATOCELLULAR CARCINOMA
Increased concentration of alpha fetoprotein in adults are most characteristically associated with:
VALINE, LEUCINE, AND ISOLEUCINE
Maple Syrup Urine Disease is characterized by an increase in which of the following urinary amino acids
CYSTEINE
Which of the following amino acids is associated with sulfhydryl groups
IDL
Which of the following is elevated in cases of DYSBETALIPOPROTEINEMIA or broad beta disease
VLDL
Which lipoprotein accounts for most turbidity observed in fasting hyperlipidemic plasma
TRANSFERRIN
Protein that migrates in the beta region at pH 8.6
LP(A)
Elevated levels of this lipoprotein (>30mg/dL) are thought to confer increased risk of premature CHD and stroke
LDL
Major cholesterol carrier and transports a large amount of ENDOGENOUS cholesterol
DURING THE CONVERSION OF VLDL TO LDL
When do the Intermediate density protein exist transiently
INTRINSIC FACTOR
Absorption of vitamin B12 requires
AN INFLAMMATORY PROCESS
The presence of CRP in the blood is an indication of
HEPATIC COMA
Blood ammonia levels are usually measured in order to evaluate
PHOTOMULTIPLIER TUBE
Most commonly used spectrophotometer detector because it visible and UV regions
ADD 5.0 MG OF GLUCOSE TO 0.1 ML OF A SERUM OF KNOWN CONCENTRATION AND MEASURE
Which of the following procedures can be used to detect proportional error in a new method for glucose
EXAMINE THE REFERENCE ELECTRODE JUNCTION FOR SALT CRYSTAL
When calibrating a pH meter, unstable readings occur for both 7.00 and 4.00 calibrators, although both can be set to within 0.1 pH unit. Select the most appropriate course of action
PO2 ELECTRODE
AMPEROMETRY is the principle of
30-60 MINUTES
At room temperature, complete clotting normally takes
THE MAXIMUM TIME LIMIT FOR SERUM/PLASMA SEPARATION ACCORDING TO CLSI IS 1 HOUR AFTER COLLECTION
Which of the following is TRUE
LITHIUM HEPARIN
Additive w/ green stopper color
OBSTRUCTION
HIGHEST elevation in the serum GGT is significantly observed in patient with
SGPT INCREASE, CHOLINESTERASE DECREASE
TRUE of SGPT and cholinesterase failure
IODINE
Amylase activity can be assayed by the direct measurement of the disappearance of starch, in this method the indicator is
15.4
What is the urea concentration if a BUN value is 10mg/dl is obtained
ALPHA 2 GLOBULINS
Ceruloplasmin and Haptoglobin migrate electrophoretically as
6.25
The conversion of protein nitrogen to protein content depends on the factor
AAS
Hollow cathode lamp used in
TISSUE NECROSIS
Elevation of tissue enzymes in serum may be used to detect
ASPIRIN
Inhibitor of PROSTAGLANDIN metabolism and commonly used as analgesic and antipyretic drug
QUINIDINE, LIDOCAINE, PROCAINAMIDE
Which of the following cardioactive drugs belong to class I
THE MATHEMATICAL EXPRESSION OF THE RELATIONSHIP BETWEEN DRUG DOSE AND DRUG BLOOD LEVEL
Pharmacokinetics is defined as
ZIMMERMAN REACTION
Test that measures those steroids with 17-keto structure
HPL
Hormone functionally, structurally and immunologically similar to GH and PRL
PLUMMER'S DISEASE
FT3 increased, FT4 Normal, with low TSH
PINEAL GLAND
It secretes MELATONIN, that decreases the pigmentation of the skin
CARBONIC ANHYDRASE
Most of the carbon dioxide combines with water to form carbonic acid which dissociates immediately into hydrogen and bicarbonate. Reaction is accelerated by
APATHY, ATAXIA, BERI-BERI
Deficiency in Vit B1
RESPIRATORY ALKALOSIS
It is observed in severe pain, aspirin dosage, hepatic cirrhosis, gram negative sepsis, salicylate and progesterone drug
AMYLASE
EARLIEST pancreatic marker
METHIONINE, ARGININE, LYSINE
Creatinine is the end product of metabolism derived from creatine. It is also by amino acids such as
CONGESTIVE HEART FAILURE
Following conditions that can cause INCREASED creatinine clearance EXCEPT
OSTWALD FOLIN
Pipet used for VISCOUS fluid
VYCOR
Glassware that can be heated up to 900oC and utilized for high thermal, drastic heat shock, and extreme chemical treatment w/ acids and dilute alkali
TYPE 2 DM
Non-insulin dependent DM
FNAB
MOST accurate tool in evaluation of thyroid nodule
3,5,3',5' TETRAIODOTHYRONINE
Major fraction of IODINE in circulation
HYPOPARATHYROIDISM
Causes of HYPERkalemia, EXCEPT
MSUD
Characterized by markedly reduced or absence of ALPHA-KETOACID DECARBOXYLASE
SUDAN BLACK B, FAT RED 7B, OIL RED O
Lipid staining dye/s
HEPATIC LIPASE, ATP-BINDING CASSETTE PROTEIN A1, LIPOPROTEIN LIPASE, ENDOTHELIAL LIPASE, LECITHIN CHOLESTEROL ACYL TRANSFERASE (AOTA)
Enzymes that participate in LIPOPROTEIN METABOLISM
SODIUM
Major extracellular cation
METABOLIC ACIDOSIS
Determine the acid-base status
pH=7.24
PCO2=44 HCO3=18
GLYCOSYLATED HEMOGLOBIN
Test that monitors DM. Long term
ALBUMIN
Migrates most rapidly toward ANODE
Presence of CRESCENT shaped bands
REPEAT ELECTROPHORESIS AND AVOID OVERLOADING THE SAMPLE
OBSTRUCTIVE JAUNDICE
Elevated CONJUGATED bilirubin in both serum and urine, decreased urine urobilinogen and decreased fecal urobilin
BILIRUBIN
FALSE DECREASED in a hemolyzed sample
NUMBER OF PEPTIDE BOND
BIURET method for total protein is dependent upon
REJECT THE SAMPLE, BECAUSE PCO2 WILL BE FALSELY DECREASED
An Arterial blood sample is received in the laboratory 45mins after collection with a Bubble in the syringe
NORMAL PCO2, DECREASED HCO3, DECREASED PH
Patient in diabetic ketoacidosis will exhibit
SWEAT CHLORIDE
BEST lab test for detecting Cystic Fibrosis
NORMAL T4, NORMAL T3 UPTAKE, NORMAL TBG
A pregnant EUTHYROID woman exhibits which of the following results in a thyroid pane
INAPPROPRIATE SAMPLE COLLECTION
A blood AMMONIA level was ordered in a patient w/ Reye's Syndrome. The results on the CLOTTED sample were normal.
MUSCULAR DYSTROPHY
Increased serum levels of CK, aldolase and AST but normal levels of ALT most likely have
INSULIN CAUSES POTASSIUM TO MOVE INTO CELLS WHICH MAY CAUSE A DROP IN K LEVELS
Why should potassium levels be monitored prior to and during administration of IV insulin
APO B48
Chylomicrons
APO A
HDL
APO-B100
LDL
4%
VLDL + HDL
3%
Cholesterol
EDTA
Anticoagulant for lipoprotein
GROWTH HORMONE
Promotes hypoglycemia
UREA CLEARANCE TEST
OVERALL kidney function
PAH
BEST measures tubular reabsorption
calcium carbonate
. Least affected by hemolysis
DECREASE SERUM MG
Hyperparathyroidism
a random error in gene replication that leads to a change
1 3s, R 4s
SPECIFICITY
w/o disease
SENSITIVITY
Given w/ disease
VARIANCE
Difference between each value and average data
EXTERNAL
Proficiency testing program
CONTROL
Closely resemble test specimen
MOST WDELY USED QC CHART
Levey Jennings
DEUTERIUM
UV light for spectrophotometer
MONOCHROMATOR
Isolates wavelength
UV
Deuterium discharge and Mercury lamp
VENOUS BLOOD
Deoxygenated blood, DARK RED, collected w/ tourniquet
UNSTABLE AT 4'C
ALP and LDH
TESTOSTERONE
Naturally occurring androgen
EXTRACT DRUGS
Thin Layer chromatography, why is a volatile organic compound mixed w/ urine
RENAL CLEARANCE OF DRUG FASTER IN NEWBORN THAN ADULTS
FALSE of drug distribution pattern
LITHIUM HEPARIN
Blood gas
30MINS, 22'C
Plastic syringe arterial blood gas