recalls CC

THE PATIENT ADDS TAP WATER TO THE URINE CONTAINER BECAUSE HE/SHE FORGETS TO SAVE ONE OF THE URINE SAMPLES

Which of the following conditions is most likely to cause a falsely high creatinine clearance result

ORTHO-TOLUIDINE (DUBOWSKI)

The only chemical method still used widely and is based on the condensation of aldosaccharides such as glucose with an aromatic amine and glacial acetic acid

ABELL KENDALL

Three step method for cholesterol determination

REMOVE PERSONS FROM IMMEDIATE DANGER

What is the first course of action to do if a fire occurs in the laboratory

BONE DISEASE

Normal serum GGT level with an elevated serum ALP is suggestive of

ACUTE CIRRHOSIS

A disorder that is generally characterized by a normal alpha 1 globulin level and a decreased alpha 2 globulin

BRIDGING EFFECT BETWEEN THE BETA AND GAMMA GLOBULIN FRACTIONS

In cirrhosis, a predominant characteristic observed on an electrophoretic serum protein pattern is a(n)

GLYCOGEN

In what form is glucose stored in the muscle and liver

HEPATOCELLULAR CARCINOMA

Increased concentration of alpha fetoprotein in adults are most characteristically associated with:

VALINE, LEUCINE, AND ISOLEUCINE

Maple Syrup Urine Disease is characterized by an increase in which of the following urinary amino acids

CYSTEINE

Which of the following amino acids is associated with sulfhydryl groups

IDL

Which of the following is elevated in cases of DYSBETALIPOPROTEINEMIA or broad beta disease

VLDL

Which lipoprotein accounts for most turbidity observed in fasting hyperlipidemic plasma

TRANSFERRIN

Protein that migrates in the beta region at pH 8.6

LP(A)

Elevated levels of this lipoprotein (>30mg/dL) are thought to confer increased risk of premature CHD and stroke

LDL

Major cholesterol carrier and transports a large amount of ENDOGENOUS cholesterol

DURING THE CONVERSION OF VLDL TO LDL

When do the Intermediate density protein exist transiently

INTRINSIC FACTOR

Absorption of vitamin B12 requires

AN INFLAMMATORY PROCESS

The presence of CRP in the blood is an indication of

HEPATIC COMA

Blood ammonia levels are usually measured in order to evaluate

PHOTOMULTIPLIER TUBE

Most commonly used spectrophotometer detector because it visible and UV regions

ADD 5.0 MG OF GLUCOSE TO 0.1 ML OF A SERUM OF KNOWN CONCENTRATION AND MEASURE

Which of the following procedures can be used to detect proportional error in a new method for glucose

EXAMINE THE REFERENCE ELECTRODE JUNCTION FOR SALT CRYSTAL

When calibrating a pH meter, unstable readings occur for both 7.00 and 4.00 calibrators, although both can be set to within 0.1 pH unit. Select the most appropriate course of action

PO2 ELECTRODE

AMPEROMETRY is the principle of

30-60 MINUTES

At room temperature, complete clotting normally takes

THE MAXIMUM TIME LIMIT FOR SERUM/PLASMA SEPARATION ACCORDING TO CLSI IS 1 HOUR AFTER COLLECTION

Which of the following is TRUE

LITHIUM HEPARIN

Additive w/ green stopper color

OBSTRUCTION

HIGHEST elevation in the serum GGT is significantly observed in patient with

SGPT INCREASE, CHOLINESTERASE DECREASE

TRUE of SGPT and cholinesterase failure

IODINE

Amylase activity can be assayed by the direct measurement of the disappearance of starch, in this method the indicator is

15.4

What is the urea concentration if a BUN value is 10mg/dl is obtained

ALPHA 2 GLOBULINS

Ceruloplasmin and Haptoglobin migrate electrophoretically as

6.25

The conversion of protein nitrogen to protein content depends on the factor

AAS

Hollow cathode lamp used in

TISSUE NECROSIS

Elevation of tissue enzymes in serum may be used to detect

ASPIRIN

Inhibitor of PROSTAGLANDIN metabolism and commonly used as analgesic and antipyretic drug

QUINIDINE, LIDOCAINE, PROCAINAMIDE

Which of the following cardioactive drugs belong to class I

THE MATHEMATICAL EXPRESSION OF THE RELATIONSHIP BETWEEN DRUG DOSE AND DRUG BLOOD LEVEL

Pharmacokinetics is defined as

ZIMMERMAN REACTION

Test that measures those steroids with 17-keto structure

HPL

Hormone functionally, structurally and immunologically similar to GH and PRL

PLUMMER'S DISEASE

FT3 increased, FT4 Normal, with low TSH

PINEAL GLAND

It secretes MELATONIN, that decreases the pigmentation of the skin

CARBONIC ANHYDRASE

Most of the carbon dioxide combines with water to form carbonic acid which dissociates immediately into hydrogen and bicarbonate. Reaction is accelerated by

APATHY, ATAXIA, BERI-BERI

Deficiency in Vit B1

RESPIRATORY ALKALOSIS

It is observed in severe pain, aspirin dosage, hepatic cirrhosis, gram negative sepsis, salicylate and progesterone drug

AMYLASE

EARLIEST pancreatic marker

METHIONINE, ARGININE, LYSINE

Creatinine is the end product of metabolism derived from creatine. It is also by amino acids such as

CONGESTIVE HEART FAILURE

Following conditions that can cause INCREASED creatinine clearance EXCEPT

OSTWALD FOLIN

Pipet used for VISCOUS fluid

VYCOR

Glassware that can be heated up to 900oC and utilized for high thermal, drastic heat shock, and extreme chemical treatment w/ acids and dilute alkali

TYPE 2 DM

Non-insulin dependent DM

FNAB

MOST accurate tool in evaluation of thyroid nodule

3,5,3',5' TETRAIODOTHYRONINE

Major fraction of IODINE in circulation

HYPOPARATHYROIDISM

Causes of HYPERkalemia, EXCEPT

MSUD

Characterized by markedly reduced or absence of ALPHA-KETOACID DECARBOXYLASE

SUDAN BLACK B, FAT RED 7B, OIL RED O

Lipid staining dye/s

HEPATIC LIPASE, ATP-BINDING CASSETTE PROTEIN A1, LIPOPROTEIN LIPASE, ENDOTHELIAL LIPASE, LECITHIN CHOLESTEROL ACYL TRANSFERASE (AOTA)

Enzymes that participate in LIPOPROTEIN METABOLISM

SODIUM

Major extracellular cation

METABOLIC ACIDOSIS

Determine the acid-base status

pH=7.24

PCO2=44 HCO3=18

GLYCOSYLATED HEMOGLOBIN

Test that monitors DM. Long term

ALBUMIN

Migrates most rapidly toward ANODE

Presence of CRESCENT shaped bands

REPEAT ELECTROPHORESIS AND AVOID OVERLOADING THE SAMPLE

OBSTRUCTIVE JAUNDICE

Elevated CONJUGATED bilirubin in both serum and urine, decreased urine urobilinogen and decreased fecal urobilin

BILIRUBIN

FALSE DECREASED in a hemolyzed sample

NUMBER OF PEPTIDE BOND

BIURET method for total protein is dependent upon

REJECT THE SAMPLE, BECAUSE PCO2 WILL BE FALSELY DECREASED

An Arterial blood sample is received in the laboratory 45mins after collection with a Bubble in the syringe

NORMAL PCO2, DECREASED HCO3, DECREASED PH

Patient in diabetic ketoacidosis will exhibit

SWEAT CHLORIDE

BEST lab test for detecting Cystic Fibrosis

NORMAL T4, NORMAL T3 UPTAKE, NORMAL TBG

A pregnant EUTHYROID woman exhibits which of the following results in a thyroid pane

INAPPROPRIATE SAMPLE COLLECTION

A blood AMMONIA level was ordered in a patient w/ Reye's Syndrome. The results on the CLOTTED sample were normal.

MUSCULAR DYSTROPHY

Increased serum levels of CK, aldolase and AST but normal levels of ALT most likely have

INSULIN CAUSES POTASSIUM TO MOVE INTO CELLS WHICH MAY CAUSE A DROP IN K LEVELS

Why should potassium levels be monitored prior to and during administration of IV insulin

APO B48

Chylomicrons

APO A

HDL

APO-B100

LDL

4%

VLDL + HDL

3%

Cholesterol

EDTA

Anticoagulant for lipoprotein

GROWTH HORMONE

Promotes hypoglycemia

UREA CLEARANCE TEST

OVERALL kidney function

PAH

BEST measures tubular reabsorption

calcium carbonate

. Least affected by hemolysis

DECREASE SERUM MG

Hyperparathyroidism

a random error in gene replication that leads to a change

1 3s, R 4s

SPECIFICITY

w/o disease

SENSITIVITY

Given w/ disease

VARIANCE

Difference between each value and average data

EXTERNAL

Proficiency testing program

CONTROL

Closely resemble test specimen

MOST WDELY USED QC CHART

Levey Jennings

DEUTERIUM

UV light for spectrophotometer

MONOCHROMATOR

Isolates wavelength

UV

Deuterium discharge and Mercury lamp

VENOUS BLOOD

Deoxygenated blood, DARK RED, collected w/ tourniquet

UNSTABLE AT 4'C

ALP and LDH

TESTOSTERONE

Naturally occurring androgen

EXTRACT DRUGS

Thin Layer chromatography, why is a volatile organic compound mixed w/ urine

RENAL CLEARANCE OF DRUG FASTER IN NEWBORN THAN ADULTS

FALSE of drug distribution pattern

LITHIUM HEPARIN

Blood gas

30MINS, 22'C

Plastic syringe arterial blood gas