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Enterobacteriaceae
facultative anaerobes, non-sporing, rod-shaped and ferments glucose with acid production
Enterobacteriaceae
oxidase negative; catalase positive and grows on peptone or meat extract media
Escherichia coli
contains Enterotoxin and Endotoxin; normally found in the GI
Enteropathogenic E.coli
an E.coli that is associated with diarrhea in infants and children
Enterotoxigenic E.coli
an E.coli that causes Traveller’s diarrhea (Montezuma’s revenge)
Enteroinvasive E.coli
an E.coli similar to shigellosis; characterized by bloody diarrhea with pus and fever
Enterohemorrhagic E.coli
an E.coli that causes bloody diarrhea with no pus and fever
Enterohemorrhagic E.coli
can cause Hemolytic Uremic syndrome that can be prevented through cooking
O157:H7
the most common serotype of EHEC that produces a powerful toxin, Verotoxin which can cause severe illness and death
Klebsiella pneumoniae
also known as Fried Lander’s bacillus mucous capsulatus
Klebsiella pneumoniae
second most common cause of Gram-negative sepsis and HAP; belongs to ESKAPE
Salmonella typhii
forms acid in glucose and mannose and causes typhoid fever
Salmonella typhii
causes rotten egg diarrhea and rose spots on the belly
Widal test
diagnostic test for Salmonella
Salmonella choleraesius
a gram-negative bacteria that causes sepsis or septicemia
Shigella dysenteriae
produces an exotoxin that is neurotoxic, cytotoxic, and enterotoxic
Proteus mirabilis
a non-lactose fermenting organism that is the common cause of UTI
Serratia marcescens
produces a red blood pigment (red colonies) and causes endocarditis
Vibrionaceae
is oxidase and catalase positive that have a single polar flagellum which requires alkaline and saline containing media for growth in laboratory
Vibrio cholerae
the causative agent of Cholera
Tetracycline and ORS
used for the treatment of Vibrio cholerae infections
Spores
a cell that certain fungi, plants, and bacteria produce to defend themselves against ecological degradation
Lactose fermenting microorganisms
organisms that produce organic acids, particularly lactic acid, lowering the pH
Pink color
color of agar plate that indicates positive result to lactose-fermenting microorganism
Yellow
color that indicates non-lactose fermenting microorganis
Virulence
the severity or harmfulness of a disease
Facultative
refers to the ability to live under more than one specific environment condition
Obligate
means to be restricted to a particular characteristic or by necessity, opposite of facultative
Cholera toxin
activates the enzyme adenylate cyclase, increased cAMP levels and stimulates the secretion of chloride ions and water into the small intestines, causing watery diarrhea
Vibrio parahemolyticus
halophilic and can be contracted through contaminated raw fish (sushi)
Helicobacter pylori
a strong producer of urease; spiral-shaped and highly motile
Urea Breath test
a diagnostic test for Helicobacter pylori
Campylobacter jejuni
has a distinctive rapid darting motility and can be found in uncooked poultry and unpasteurized milk
Haemophilus influenzae
a respiratory organism that can cause meningitis in children, epiglottitis, septic arthritis, and sepsis
Haemophilus ducreyi
causes chancroid ulcers or soft chances
Haemophilus vaginalis
causes bacterial vaginosis and a fishy vaginal discharge
Bordetella pertussis
causes whooping cough and can be prevented by DPT vaccine and can be treated by Macrolides
Legionella pneumophila
causative agent of Legionellosis or Legionnaires disease (pneumonia from airconditioning systems) and Pontiac fever
Brucella
also called Fever of Crate, Rock fever of Gibraltar, Bang’s fever, Undulant fever, Malta fever
Brucella
its mode of transmission includes open skin, ingestion, and inhalation of infectious aerobes
Yersinia pestis
causes Bubonic and pneumonic plaque
Yersinia pestis
its reservoirs are rodents and squirrels through a flea bite or animal contact
Yersinia enterolitica
from unpasteurized milk that causes enterocolitis, arthritis, rash, and diarrhea
Francisella tularensis
its reservoirs are rodents and squirrels through a vector: a tick or deerfly
Francisella tularensis
can cause tularemia, rabbit fever, or deer fly fever and can occur in ulderoglandular, oculoglandular, and pulmonary form
Bartonella henselae
causes cat-scratch disease
Bartonella bacilliformis
can cause Carrion’s disease; Vector: Sandflies
Bartonella quintana
causes Trench fever or 5-day fever; Vector: human body Louse
Neisseria meningitides
a diplococci that causes meningitis and meningococcemia
Neiserria gonorrhoeae
can cause gonorrhea, pelvic inflammatory disease and ophthalmia neonatorum
Bacteroides fragilis
can cause brain abscess, GIT abscess, and UTI
Pseudomonas
are gram-negative rods that are widely distributed in soil and water
Pyocyanin
produces a blue green color
Pyoverdin
produces a green color
Pyorubin
produces a red color
Pyomelanin
produces a black or brown color
Pseudomonas aeruginosa
releases a sweet grape like odor and flouresced blue green on culture media when exposed to UV light
Piperacillin
the most effective tx of diseases caused by Pseudomonas aeruginosa
Rickettsia
originally thought to be viruses because growth is enhanced by sulfonamides
Rickettsia rickettsii
causes Rocky Mountain Spotted Fever
Vector: Wood/Dog tick
Rickettsia akari
causes Rickettsial pox
Vector: mites
Rickettisa australis
causes Queensland Tick fever
Rickettsia prowazekii
causes Brill-Zinsser disease/Epidemic typhus
Vector: Pediculus Human Louse
Rickettsia typhi
causes Murine typhus/ Endemic typhus
Vector: Rat flea
Rickettsia tsutsugamushi
causes scrub typhus
Vector: mite larvae
Doxycycline
the DOC for all types of rickettsia disease
Coxiella burnetii
causes Q fever and is better stained with GIMINEZ
Chlamydia
are energy parasites that can synthesize their own protein and has a unique cell wall with no peptidoglycan
Chlamydia trachomatis
its manifestations include trachoma—eye infection, and urethritis
Chlamydia psittaci
also known as Psittacosis or Ornithosis and can be contacted with birds
Spirochetes
are extremely thin and can be very long and tightly coiled helical cells with tapered ends
Treponema pallidum
causative agent of Syphilis/ Social disease/ French disease
Acquired syphilis
syphilis can be transmitted through sexual contact or blood
Congenital syphilis
syphilis can be transmitted from mother to fetus
Congenital syphilis
Manifestions are called as Hutchinson’s triad (Hutchinson’s teeth, Interstitial keratitis, and Eight nerve deafness)
Primary stage
stage of syphilis; Hallmark: chancre
Secondary stage
stage of syphilis; Hallmark: condylomata lata
Latent stage
a stage of syphilis that show no signs and symptoms of active syphilis but remain seroactive
Tertiary stage
a stage of syphilis; Hallmark: GUMMA or localized granulomatous dermal lesions
Borrelia recurrentis
causative agent of relapsing fever with humans as reservoir and body louse as vector
Borrelia burgdorferi
causative agent of Lyme disease
Vector: Ixodes tick
Borrelia vincenti
causes Vincent’s angina
Fletcher’s media
Leptospira is cultured on this specialized media
Leptospira interrogans
causes Leptospirosis and Weils Disease
Reservoir: Rodent’s urine and feces
Acid-fast organisms
resist decolorization by acid or alcohol because of Mycolic Acid
Mycobacterium tuberculosis
also known as Tubercle Bacilli or Koch bacilli
Sputum smear/ ATB smear
the gold standard diagnostic test for Mycobacterium tuberculosis
Lowenstein-Jensen medium
Mycobacterium tuberculosis can be grown on this medium
Mycoplasma pneumonia
a wall-less organism and the smallest known free-living self-replicating prokaryotic cell
Mycoplasma pneumonia
produces Walking Pneumonia/Atypical pneumonia
Gram positive
contains Teichoic acid in their cell wall and appear purple under magnification
Alpha hemolysis
reduces hemoglobin to methemoglobin causing a greenish zone to surround the colony
-Streptococcus pneumonia
-Streptococcus viridans
-Streptococcus mutans
Beta hemolysis
causes a clear zone hemolysis on blood agar
-Streptococcus pyogenes
-Streptococcus agalactiae
Gamma hemolysis
has no effect on RBC; aka Non-hemolytic
-Streptococcus bovis
Streptococcus pyogenes
can cause strep throat and recurrent tonsilitis
Streptococcal pyogenes
also known as Erysipelas/Scarletina since it can cause scarlet fever
Toxin: erythrogenic toxin
Sreptococcal pyogenes
manifestations of this bacteria include strawberry red tongue aka sand-paper rash/ sunburn like rash
Dick test
a laboratory test designed to indicate whether or not a person is immune to scarlet fever
Streptococcus pyogenes
can cause Toxic shock syndrome, Pyoderma, Necrotizing fasciitis, and Acute glomerulonephritis
Group A Streptococcus
a group that is sensitive to bacitracin