Silver Impregnation
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7 Terms
von Kossa stain
Gordon and Sweets’ stain
GPAMS stain
Grocott’s
Masson-Fontana
What are the silver impregnation stains? (5)
Calcium phosphate in bone and other calcified tissues
Metabolic bone disease
What is the von Kossa stain used for ?
+ eg of disease
Reticular fibres
Breakdown can indicate cirrhosis or lymphoma
What is the Gordon and Sweet’s stain used for?
example of conditions (2)
Basement membranes
eg. Glomerulus in kidney
What is a GPAMS stain for?
give an example.
Fungal hyphae (carbohydrates)
What is Grocott’s stain used for?
Melanin/lipofuscin
Skin cancer
Can differentiate cryptococcus neoformans.
What is Masson-Fontana stain for?
example (2)
Oxidation of glycol groups in tissue result in formation of aldehyde. Aldehydes are a reducing agent, and direct deposition of metallic silver.
What is the general principle of silver impregnation?
Note 
Flashcards (22)