exogenous pathway
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Last updated 3:10 PM on 2/27/23
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7 Terms
1
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exogenous pathway is a process from which MHC class?
Class 2
2
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first step of exogenous pathway?
invariant chain binds MHC class I a and B chain, blocking endogenous peptides from binding
3
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second step of exogenous pathway?
MHC II complex is routed through golgi to endocytic pathway compartments
4
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third step of exogenous pathway?
invariant chain is degraded, leaving clip fragment
5
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fourth step of exogenous pathway?
exogenous antigen is taken up, degraded, routed to endocytic pathway compartments
6
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fifth step of exogenous pathway?
HLA-DM mediates exchange of CLIP for antigenic peptide
7
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6th step of exogenous pathway?
MHC II peptide is transported to plasma membrane
Note 
Flashcards (20)