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Stroop task
cognitive interference where delay in reaction time bc mismatch w stimuli
word and colour
introspection
examine yourself and ur conscious thoughts and feelings
within thinking
structuralism
taking a complex phenomenon and breaking it down into make makes it what it is
behaviourism
human behaviour, associated learning emphasized
rejected mind (can't see it, cant study)
drawback: not understanding genesis of mental behaviour
doesn't consider motivations, moods, fears and desires
based on conditioning
cognitivism
rejected notion that only behaviour should be studied
mind and processing info important
2 types: serial and parallel models
serial model
step by step
if thinking was like this, processing would be very slow
(cognitivism)
parallel
multiple steps happen simultaneously
(cognitivism)
usage and utility
mental resources are limited, cant be aware of everything
some stuff enter some dont
(cognitivism)
variability in cognition
within-subject differences: I am great with faces but not with names-> mental abilities within self
between subject differences: I might be good at faces but Robia isnt -> mental abilities differ between us
flexibility
mental abilities change
ex, worse: brain damage
Edwin smith papyrus
how to treat trauma back in days
open skull to relieve pressure
was this paper thing with 48 cases some w brain injury
hinted at localization
inkling that mind comes from brain and diff parts of brain do stuff
cardiac hypothesis
mind comes from heart
thought brain was really insignificant and heart seen as seat of intelligence
alcamaeon of croton/galen: brain hypothesis
brain is what the mind is
heart gives brain oxygen
rationalism
pursuit of truth through reasoning
descartes
monism/dualism
rationalism... he believed mind and brain relationship, each diff things
thought pineal gland was special bc is directly in middle of brain
thought pineal gland was the interphase between brain and soul
(don't need brain for reflexes though ac... brain can control reflexes)
rationalism incorrect
neuron doctrine
rejection of Golgi's syncytium proposal
synapse and neural communication
saying brain made up of cytoplasm but the saying brain made of neutrons, separated by synapses
REALITY: brain communicates w neutrons w synapses
aggregate field theory
1/2 competition theories of brain organization
thinking all brain works together to do what's done
no specialization
localization of function
1/2 competition theories of brain organization
different parts specialize in certain things
phrenology
wrong
think bigger area, more associated w ability
not true bc lets say u become more moral, nothing is growing bc skull
brodman's map
mapped cerebral cortex
just shows layering arrangement
evidence for localization
Paul broca, wernicke
john Jackson (Jacksonian march, said aboral mental state may result from structural brain damage)
Enfield (brain mapping w electrocortical stimulation of brain surface -> electrode pass current to brain area and see what happens
Phineas Gage(iron rod), patient hm(removed temporal lobe, anterograde amnesia)
Alexander luria
whole-person view of brain injury
brain areas work together: NETWORKS
see brain injury as person
stressed not all brain areas are equal
non-human studies
animal lesion study to see effect on behaviour
functional imaging techniques
reveal physiological activity in the brain. e.g. PET,SPECT, EEG, fMRI
human lesion studies
look at brains with brain injuries and see how this alternation affects function
cognition
models how thinking works
neuroscience
allows us to see how brain gives rise to thinking
which parts of brain are used when problem solving
developmental cognitive neuroscience
how mind and brain change over time
social cog neuroscience
how and why we're social and do what we do
self-monitoring in social situations
cultural cognitive neuroscience
display rules and emotion regulation
tries to understand the effect culture has on brain function
clinical cognitive neuro
understanding changes in mind and the brain associated w psychological illness
rehabilitation cognitive neuro
how brain repairs after trauma
glial cells
hold brain together but also communicative properties:
astrocytes, microglial cells, Schwann cells and oligodendrocytes
astrocytes
incredibly flexible
blood-brain barrier
respond to brain damage
microglial cells
eat dying/dead neurons so they dont become a problem
Schwann/oligodendrocytes
Myelinate/insulate axon: helps faster neurotransmission
motorneurons
send motor signals
sensory neurons
absorb sensory information
(chemoreceptors absorb taste)
interneurons
can communication all kinds of info
what u see, decision u make, how valuable something is
most neurons
dendrites
receive signals
always on cell body
branch off of neurons
axon
path down which a signal is transmitted
terminal
terminal
SENDS signals
how does neuron send signal
cell membrane = semi permeable
certain ions in some pushed out
selective permeability
A property of a plasma membrane that allows some substances to cross more easily than others.
number of signals sent =
more intense stimulus
signal down axon
moves left to right to the terminal
signal travels passively through cell
saltation: jumping between nodes
multiple sclerosis
autoimmune disorder where immune system attacks myelin
if occurs in motorfibers: might have difficulty in movement
somatosensory fibers: develops numbness in hand
temporal lobe: degraded memory
amyotrophic lateral sclerosis
a rapidly progressive neurological disease that attacks motor neurons responsible for controlling voluntary muscles causing weakened muscle
stroke
abnormal interrupting of blood supply to nervous system
ischemic strokes, caused by blockage/blocking of brain artery
dopamine
made in substantial nigra and ventral segmental area
help in higher-level cognition : help keep stuff in mind time to time, working memory
voluntary movement
reward/reinforcement learning
dysfunction levels:
parkinsons, psychotic thoughts/behaviour, addiction
norepinephrine
produced in locus coeruleus
linked to mental arousal: attention
memory
mental flexibility (switch gears)
mood
dysfunction levels: alzheimers, bipolar, depression, visuspatial neglect
serotonin
made in raphe nucleus
strongly linked to mood
low levels associated with depression
can affect gut
psychotic thoughts/behaviour
acetylcholine
made in basal forebrain
linked with sensory processing: making sense of sensory stuff ur taking in
movement: PNS, dysfunctional levels associated w weakness
ACH IN BRAIN NOTHING TO DO W MOVEMENT
alzheimers: each low
myasthenia graves: movement issue in PHS
Psychopharmacology
heroes-dodson curve
suggests optimal level of neurotransmitters of where ideal neurotransmitter would be for best memory, mood, etc.
as you move away from peak, deviate from optimal functioning
changing one neurotransmitter can change other ones
consider prescriptions, observations etc
human spinal cord
carries nerves in body
motor function and touch function
MOTOR GOES DOWN TO CONTROL BODY
TOUCH GOING UP to brain
Corticospinal tract
motor fiber
controls voluntary movement
starts in frontal lobes
if someone has stroke on left, right side will feel weak
MAJOR SOMATOSENSORY TRACTS
1) medial lemniscus tract
- proprioception: knowing where ur limbs are, located in muscle fibers, if didn't have proprioception, would just fall in dark bc dont know how body is oriented
- touch: how whether you have a soft touch vs hard touch somewhere : pain and temperature
2) lateral spinothalamic tract
- carry sensory info to brain
- pain receptor, temperature receptor
Dorsal ___
carries touch info
ventral ___
motor
dermatomes
different parts of body controlled by different parts of spinal cord nerves
frontal lobe
boss of brain
parietal lobe
touch and attention
occipital lobe
vision
temporal lobe (Genera)
hearing, speech and memory
primary sensory cortex
regions of the cerebral cortex that initially process information from the senses
motor cortex
an area at the rear of the frontal lobes that controls voluntary movements
association cortex
essential for more complex stuff (language represented and retrieved problems solved)
cerebral cortex outside the primary areas
limbic system
neural system (including the hippocampus (memory), amygdala (fear processing emotion), and hypothalamus(hormone), thalamus (sensory relay station)) located below the cerebral hemispheres; associated with emotions and drives.
cerebellum
where more neurons w huge dendrites are
damage can cause speech damage and slur
alcohol inhibits cerebellum function
important w VOLUNTARY MOVEMENT (posture, speech, coordination)
receive info and consolidate information to smooth actions
protecting brain
skull, dura, pia mater, meninges
Computerized Axial Tomography (CAT)
3d Xray
pass radiation, some parts absorb some dont
use absorption rate to reconstruct and can take slices
good for emergency medicine
smri
brain structure (structural magnetic resonance imaging) (finer image than CT)
detailed image in fast time
like big magnet, atoms line up in magnetic field, use radio frequency pulses that send signals to knock atoms out of alignment
increasing magnet = increase resolution
voxel
volumetric pixel that make up brain space
helps us understand what brain areas are for
lesion overlap technique
30 people with brain injury cant form memory
take smri with all 30 and lay 30 images over and take average and see where the most common overlap of brain damage is for this group
diffusion tension imaging (DTI)
measures the diffusion of water in the brain tissue, permitting the imaging of the white matter tracts
structural
track water w fractional anisotropy
get info with mri
EEG
functional analysis
electrodes on scalp get electrical activity
good temporal rolsution but weak spatial resolution
computing event related potentials
50-60 trails increases your confidence
event related potential (ERP)= ex: do memory retrieval task 50 times, take 50 waves from each electrode and take average
weak spatial resolution
ECoG
EEG directly on brain
high spatial resolution
low temporal resolution
PET scan
a visual display of brain activity that detects where a radioactive form of glucose goes while the brain performs a given task
gamma ray is measured and goes into computer to make image
high temporal
low spatial
fmri
a form of magnetic resonance imaging of the brain that registers blood flow to functioning areas of the brain
neuromuscular coupling: can measure changes in blood flow to activity
B lood
O xygenated
L evel
D ependent
good spatial, weak temporal
subtraction method
stimulus - control state = activity due to stimulus
scan 40-50 times
average
subtract
transcranial magnetic stimulation (TMS)
the use of strong magnets to briefly interrupt normal brain activity as a way to study brain regions
fundamentals of experimental design
1) why are we studying, what will learning more help us understanding the brain/help others?
2) literature definition (Ex: working memory is ability to keep info in mind from moment to moment)
3) operational definition
(Ex: how will working memory be set up in ur experiment-> rmbr location of flashing lights on screen)
transduction
take life info and turn it into neural signal in eyes
perception makes sense of neural (transduced) signals
ex: captures light info from environment
pupil
The opening through which light enters the eye
lens
Focuses light onto retina
refracts light
sensory and photo receptors located here
retina
Light sensitive layer of the eye; contains rods and cones
cones
color receptors
rods
Retinal receptors that detect black, white, and gray
dim lighting and motion
fovea
Contains the highest concentration of cones
info consolidated by____
neurons
interprelation
dont have holes in vision bc use what other eye is seeing to fill gaps
(blind spot where dont have photoreceptors where optic nerve leaves eye)
blind spot
the point at which the optic nerve leaves the eye, creating a "blind" spot because no receptor cells are located there
LGN
after right side and left side cross at optic chasm, stops at LGC, then radiated back to occipital cortex
primary visual cortex
the region of the occipital lobe whose primary input is from the visual system
damage to right thalamus would =
left visual field impaired
retinotopic mapping
An arrangement of neurons in the visual system whereby signals from retinal ganglion cells with receptive fields that are next to each other on the retina travel to neurons that are next to each other in each visual area of the brain
map at back of eye on brain
scotoma
blind spot in vision
bilateral damage to visual cortex
blindness
eyes sense light and stuff
but first unit in occipital lobe damaged so cortical blindness
hemianopsia
blindness in half of the visual field of one or both eyes
(can be bc m.s. and myelin attacked)