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Vocabulary-style flashcards covering key terms and definitions from the Skeletal System lecture notes.
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Skeletal system
The body system composed of bones, cartilage, ligaments, and bone marrow that provides support, protection, movement, and mineral storage.
Cartilage
Connective tissue; precursor to most bones in development and covers joint surfaces.
Ligaments
Fibrous tissues that connect bones at joints to provide stability.
Bone marrow
Soft tissue inside bones; red marrow forms blood cells and platelets, yellow marrow stores fat.
Osteogenic cells
Stem cells on bone surfaces that differentiate into osteoblasts.
Osteoblasts
Bone-forming cells that synthesize bone matrix and promote mineralization.
Osteocytes
Mature bone cells derived from osteoblasts; reside in lacunae and communicate via canaliculi.
Lacunae
Small cavities within bone matrix that house osteocytes.
Canaliculi
Microscopic channels that connect lacunae, enabling nutrient and signal exchange between osteocytes.
Osteoclasts
Bone-dissolving cells; large with multiple nuclei; resorb bone at the ruffled border.
Osteon
The structural unit of compact bone, consisting of concentric lamellae around a central canal.
Compact bone
Dense bone tissue; forms outer layer and encloses spongey bone in an osteon-rich matrix.
Spongy bone
Porous interior bone tissue with trabeculae; houses bone marrow and vessels.
Bone matrix
The extracellular material of bone composed of organic collagen and inorganic calcium phosphate.
Osteoid (organic matrix)
Part of the bone matrix rich in collagen that becomes mineralized.
Calcium phosphate
Inorganic mineral salt in bone matrix providing rigidity.
Rickets and osteomalacia
Bone softening diseases due to mineral deficiencies in the diet or metabolism.
Medullary cavity
Central cavity within a bone shaft that contains bone marrow.
Articular cartilage
Hyaline cartilage covering the ends of long bones to ease joint movements.
Epiphysis
Expanded end of a long bone that participates in joints and is filled with spongy bone.
Diaphysis
Shaft or long, cylindrical part of a long bone.
Endosteum
Thin connective tissue lining the internal surfaces of all bone tissue.
Periosteum
Fibrous, vascular sheath covering the outer bone surface; collagen fibers connect with tendons.
Fontanels
Soft spots in the infant skull where font material has not yet ossified; allow skull compression during birth.
Red bone marrow
Marrow that produces blood cells; abundant in children.
Yellow bone marrow
Fat-containing marrow that predominates in adults within long bones.
Ossification
The process of bone formation.
Intramembranous ossification
Bone develops directly from mesenchyme; forms flat bones like the skull; fontanels indicate unossified regions in infants.
Endochondral ossification
Bone replaces hyaline cartilage model; forms most bones except flat bones of the skull.
Perichondrium
Dense connective tissue that envelops cartilage and contributes to bone formation in endochondral ossification.
Periosteum vs Endosteum
Periosteum covers outer bone; endosteum lines internal bone surfaces.
Epiphyseal plate (growth plate)
Cartilaginous zone in long bones where growth occurs; becomes an epiphyseal line in adults.
Osteoclast activity
Resorption of bone minerals into the blood, often increased during calcium needs.
Calcitriol
Active vitamin D; increases calcium absorption and mobilizes calcium from bone.
Parathyroid hormone (PTH)
Raises blood calcium by stimulating bone resorption, kidney reabsorption, and calcitriol synthesis.
Calcitonin
Lowers blood calcium by promoting bone deposition and reducing calcium reabsorption.
Growth hormone
Stimulates bone growth and ossification.
Estrogen
Promotes bone deposition and maintenance; important for bone density, especially post-menopause.
Testosterone
Promotes ossification and bone growth in males.
Vitamins D, A, C
Vitamins that support bone deposition, repair, and overall bone health.
Ossification centers
Sites where bone formation begins; primary forms in endochondral ossification and intramembranous ossification sites.
Growth plate closure
End of bone elongation when the epiphyseal plate is depleted of cartilage and replaced by bone.
Joints
Connections between bones; classified structurally as fibrous, cartilaginous, or synovial.
Fibrous joints
Joints bound by collagen fibers; little mobility (e.g., skull sutures).
Cartilaginous joints
Joints connected by cartilage; allow limited movement (amphiarthrosis).
Synovial joints
Freely movable joints with a joint cavity and synovial fluid (diarthrosis).
Synovial joint anatomy
Contains joint cavity, synovial fluid, articular cartilage, joint capsule, synovial membrane, and sometimes discs or menisci.
Menisci
Crescent-shaped cartilage in the knee that improves fit and absorbs shock.
Bursae
Fluid-filled sacs that cushion tendons and reduce friction.
Six types of synovial joints
Ball-and-socket, hinge, pivot, plane (gliding), saddle, and condylar joints.
Ball-and-socket joint
Sphere-like head fits into cuplike socket; allows multiaxial movement (e.g., shoulder, hip).
Hinge joint
Convex surface into a concave surface; movement mainly in one plane (e.g., elbow, knee).
Pivot joint
Bone spins around a longitudinal axis (e.g., radioulnar joints; atlas–axis).
Condylar (ellipsoid) joint
Oval convex surface fits into a depressions allowing two-plane movement (e.g., knuckles).
Saddle joint
Saddle-shaped surfaces permit two-plane movement; enables thumb opposition.
Plane (gliding) joint
Flat or slightly curved surfaces that glide; movement in two planes (e.g., intercarpal).
Cartilage wear diseases
Osteoarthritis: wear of articular cartilage; Rheumatoid arthritis: autoimmune synovial inflammation.
Gouty arthritis
Joint inflammation due to uric acid crystal deposition.
Rheumatism
Broad term for musculoskeletal pain; rheumatologist treats these conditions.
Vertebral column components
33 vertebrae and 23 intervertebral discs; cervical, thoracic, lumbar, sacral, coccygeal.
Spinal curvatures
Cervical, thoracic, lumbar, and pelvic curvatures; contribute to bipedal posture.
Atlas (C1) and Axis (C2)
First two cervical vertebrae; atlas supports the head, axis provides rotation via the dens.
Intervertebral discs
Nucleus pulposus surrounded by annulus fibrosus; can herniate.
Paranasal sinuses
Air-filled cavities named for the bones they reside in: frontal, sphenoid, ethmoid, maxillary.
Auditory ossicles
Three tiny bones (malleus, incus, stapes) in each middle ear.
Hyoid bone
A unique bone that does not articulate with another bone; anchor for tongue muscles.
Cranial vs facial bones
Cranial bones form the cranium; facial bones shape the face and support cavities.
Infant skull anatomy
Fontanels are soft spots where intramembranous ossification is incomplete, allowing birth compression.
Sutures
Fibrous joints between skull bones; appear as seams.
Cranial cavities
Includes the cranial cavity, orbits, nasal cavity, and oral cavity.
Vertebral foramen and canal
Opening for the spinal cord (vertebral foramen) and the spinal canal (formed by all vertebral foramina).