Immunohematology Lecture (Midterms) - Other Blood Groups

Glycosphingolipids

What kind of glycoprotein is lewis antigen

Chromosome 19

Le genes is located on the what chromosome

Non-secretors

Le(a+b-) are what secretors

Secretors

Le(a-b+) are what secretors

Secretors and Nonsecretors

Le(a-b-) are what secretors

Heliobacter pylori

Leb has receptors for what bacteria

Lex

This Lewis antigen is a marker for Reed-Sternberg cells of hodgkin’s disease

Anti-Lea

Most commonly encountered antibody of the Lewis system

MN

This MNSs U is associated with glycophorin A

Ss

This MNSs U is associated with glycophorin B

Chromosome 4

MNSs U is located on what chromosome

MNS antigen

this antigens are important in paternity testing

Chromosome 22

P antigen is located on what chromosome

Anti-P

Naturally occurring alloantibody in the sera of all Pk

Donath Landsteiner Antibody

IgG biphasic hemolysin associated with paroxysmal cold hemoglobinuria

Anti-PP1Pk

Associated with spontaneous abortions in early pregnancy (lgG)

i antigen

This Blood group I antigen is rich at birth and infant

Chronic Dyserythropoietic Anemia Type II or HEMPAS

Associated with much greater i activity on red cells than control cord cells

Antigen I

This I antigen is rich in Adult red cells

Pathologic I antibodies

This antibody is a potent cold agglutinin that demonstrates high titer reactivity and reacts over a wide thermal range (0 to 30C)

Anti-I

An IgM aggutinin. Associated with infectious mononucleosis

Chromosome 7

Kell antigens is found in this chromosome

Sulfhydryl reagents

Kell antigen is destroyed or inactivated by this regeants

Kell antibodies

Most common antibody seen in blood bank

K antigen

Rated second only to D antigen in terms of immunogenicity

McLeod Phenotype

A rare phonotype with decreased Kell system antigen

McLEOD syndrome

Common among males suffering from chronic granulomatous disease. Muscular dystrophy, Acanthocytosis, and Reticulocytotic happens.

Red cells

Kell antigen is only found on what

Kx antigen

McLeod Phenotype lacks this antigen

Chromosome 1

Duffy antigen is found on this chromosome

Fy(a-b-)

A Duffy antigen that is important antrhopological markers for african blacks

Duffy antigen

Antigens that are easily destroyed by common proteolytic enzymes

Plasmodium vivax
Plasmodium knowlesi

Duffy antigens shown to resist infecton caused by these parasite

Chromosome 18

Kidd antigens is found on this chromosome

Jk(a-b-)

This kidd antigen resist lysis in 2m urea and occurs in Mongoloids

Kidd antibodies

most notorious antibody in blood bank

Dosage effect

A phenomenon where by an antibody reacts more strongly with a red cell carrying a double than with a red cell carrying a single dose

Chromosome 19

Blood group Lutheran is located on this chromosome

Blood group lutheran

This blood group is closely associated with the secretor lotus

Lu (a-, b-)

This antigen results from three different genetic backgrounds

Dia antigen

Useful tool in anthropological studies of monoglian ancestry

CH/RG antigens

Antigenic determinants of human complement C4

Anti-CH/RG

Antibody that can be neutralized by fresh human serum

CH/RG

Consists of 9 antigens

X chromosome

Xga allele is located on the chromosome

Xg systems

This blood group system is associated more in women than males

Bg systems

Blood group systems that is related to human leukocyte antigens on RBCs

Cromer (021)

Associated with decay accelerating factor

Dombrock (014)

Associated ADP-ribosyltransferase 4

Gerbich (020)

Produced in glycophorin C and D

Indian (IN : 023)

Associated with CD 44

Scianna (SC : 013)

Associated with erythroblast membrane-associated protein

Cartwright

Found on the protein acetylcholinesterase

MNS, Kell, and Duffy

Blood groups that are well developed at birth

U-

This MNSs U is common among blacks

U+

this MNSs U is common among whites

Universal

The U in MNSs U group means