GI drugs

cimetidine

blocks histamine receptors to stop gastric acid production

omeprazole

hydrogen potassium ATase enzyme, suppressing the production of gastric acid

sucralfate

coats ulcer via chemical reaction

aluminum hydroxide

alkaline compound that neutralizes gastric acid

misoprostol

replaces endogenous prostaglandin-E

ondansetron

blocks 5-HT3 serotonin receptors in the CTZ and vagal nerve

dimenhydrinate

blocks release of histamine from H1 receptors in the inner ear and CTZ

metoclopramide

blocks dopamine receptors reducing N/V increasing peristalsis

psyllium

absorbs water from intestines, stimulates peristalsis, adds bulk

docusate sodium

changes surface tension of stool, increases absorption of water

bisacodyl

stimulates intestinal motility in the colon

diphenoxylate/atropine, loperamide

decreases intestinal peristalsis

alosetron

blocks 5-HT3 receptors in the GI tract

lubiprostone

prostaglandin E deviates that stimulate 5-HT4 receptors and activates Cl channels

sulfasalazine

sulfamide antibiotic

azathioprine

inhibits production of Band T lymphocytes