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What is a neuron?
The cell type used for both structure and function within the nervous system
What are the three types of neurons?
Sensory neurons, interneurons, motor neurons
What do sensory neurons do?
Transmit information from a sense receptor to the brain or spinal cord
What do interneurons do?
Integrate information within the brain or spinal cord and connect sensory and motor neurons; located within the central nervous system
What do motor neurons do?
Transmit information from the brain or spinal cord to a muscle or gland, causing muscle contraction or gland secretion
Which division of the nervous system includes the brain and spinal cord?
The central nervous system
What is a neurotransmitter?
A chemical that affects an adjacent cell
What are the two types of neurotransmitters?
Excitatory and inhibitory
Which type of neurons have long dendrites and shorter axons? Short dendrites and longer axons?
Sensory neurons have long dendrites and short axons, motor neurons have short dendrites and long axons
What do dendrites do?
Receive information and stimuli
What do axons do?
Carry signals to the next neuron
What is a synapse?
The connection between two neurons
What is the synaptic cleft?
The gap between the presynaptic and the postsynaptic cell
What are the synaptic vesicles?
Vesicles that carry neurotransmitters and ions
What are glial cells?
Non-conducting, support cells within the nervous system
What is the typical resting potential of a neuron?
-70 millivolts
How are the concentration gradients of NA+ and K+ maintained?
Active transport; through sodium potassium pumps
What are the key points about hyperpolarization?
-membrane potential gets farther away from 0
-inhibitory
-loss of K+ ions
What are the key points about depolarization?
-membrane potential gets closer to 0
-excitatory
-gain of NA+ ions
What is the critical value caused by depolarization called? At what charge does it occur?
A threshold, and it occurs at -55 millivolts
What is a wave of depolarization called?
Action potential
What kind of response is it when there are only two options: a huge response, or no response at all?
An all or nothing response
What are the 5 states of nerve impulse transmission? Describe them.
Resting state, Depolarization, Rising phase of the action potential, Falling phase of the action potential, and Undershoot
Are NA+ and K+ channels open or closed during the resting state?
Closed
What triggers depolarization? What channels open during this, and what occurs if the threshold is reached?
An outside stimulus triggers depolarization, during which sodium channels open, and if the threshold is reached, an action potential occurs
During repolarization, how is the membrane charge reestablished?
Potassium channels open, which permits K+ flow
What would the membrane charge graph look like if no threshold was reached?
There would be no spike/peak, which represents the action potential
What are the 3 steps of an action potential being conducted?
The action potential is generated from NA+ flowing inwards across the membrane at one specific location. Depolarization of the action potential spears to a neighboring location, forming the action potential there (the original location repolarizes). The depolarization/repolarization process repeats, carrying the action potential down the axon
What are the two types of glial cells that produce myelin sheaths?
Schwann cells and oligodendrocytes
How does a myelin sheath speed impulse transmission?
It blocks and covers ion channels, causing a signal to jump from place to place, and skip over some locations, so messages can be sent quickly
If myelin sheaths hardened and deteriorated, how would the nervous system function be affected?
Loss of the insulation from the myelin sheaths leads to a disruption of action potential, so the membrane can't depolarize
What occurs to synaptic vesicles as Ca2+ levels increase?
They fuse with the presynaptic membrane, and release neurotransmitters into the synaptic cleft, so they can move to the postsynaptic membrane
What is contained within the synaptic vesicles?
Neurotransmitters
What are the 3 steps of an action potential being transmitted across a synapse?
Synaptic vesicles with neurotransmitters arrive at the end of the presynaptic cell. An increase in calcium ions causes vesicles to fuse with the membrane and release the neurotransmitters. Neurotransmitters trigger receptors on the postsynaptic membrane, and then travel back to the original cell
Insulin
Hormone produced by the pancreas that helps to decrease blood sugar. lowers blood glucose levels by enhancing the rate of glucose uptake and utilization by target cells, which use glucose for ATP production.