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Name the components of the lymphatic system
A one way network of lymphatic vessels (lymphatics) that collect excess protein containing interstitial fluid
Lymph
Lymph nodes
Lymphatic organs
List the functions of the lymphatic vessels
Return excess fluid to the blood
Return leaked protein to the blood
Carry pathogens to lymph nodes
Carry absorbed fat from the intestines to the blood
Describe the source of lymph?
Interstitial fluid that enters the lymphatic vessels . Originates from blood plasma that leaks out of blood capillaries into the spaces around cells
Which structural modifications are responsible for the increased permeability of lymphatic capillaries?
Mini valves and collagen fibers
What are lymphoid tissues?
specialized parts of the body that provide the structural basis of the immune system by housing phagocytic cells and lymphocytes to prepare for an attack. there are two main types
diffuse lymphoid tisse
lymphoid follicles (nodules)
describe diffuse lymphoid tissue
loose arrangement of lymphoid cells and some reticular fibers. they are found everywhere.
describe lymphoid follicles
solid spherical bodies consisting of tightly packed lymphoid cells and reticular fibers (growing center) . they contain germinal centers of proliferating B cells.
Describe the distribution/location of lymphatic capillaries
they weave between tissue cells and blood capillaries and are not found in bone, bone marrow or teeth and are highly limited in the central nervous system. their main function is to collect excess interstitial fluid (which becomes lymph) and begin its transport back toward the bloodstream. lymph transport begins here
Describe how the lymph flows back into the venous system
(Lymphatic capillaries=> Collecting lymphatic vessels=> lymphatic trunks=> lymphatic ducts=> veins)
Lymphatic vessels are low pressure vessels that lack a pump. Describe the mechanisms that ensure lymph transport back into the venous system
milking action of skeletal muscle fluid
pressure changes in thorax during breathing
valves to prevent back flow
pulsations of nearby arteries
contractions of smooth muscle in walls of lymphatics
what are primary lymphoid organs
areas where lymphocytes , T and B cells mature (daycare) - red bone marrow and thymus
what are secondary lymphoid organs
areas where mature lymphocytes first encounter their antigen and become activated
Describe the general location, histological structure, and functions of lymph nodes
most are embedded deep in connective tissue but some are nearer to body surface in inguinal, auxiliary and cervical regions.
histologically contain afferent lymphatic vessels, sub scapular sinuses, medullary sinuses, hillum and efferent lymphatic vessels
function to cleanse the lymph and immune system activation.
Explain why there is a higher number of afferent lymphatic vessels associated with lymph nodes compared to efferent lymphatic vessels
to allow lymphocytes and macrophages time to function
Name the functions of the spleen
filter system for your blood (daycare)
site of lymphocyte proliferation and immune surveillance and response
clenses blood of aged blood cells and platelets
stores broken-down products of rbcs for later use
stores blood platelets and monocytes for release into blood when needed
may be cute of fetal erythrocyte production
Define MALT and list its major components
mucosa associated lymphoid tissue
found in mucosa of respiratory tract, genitourinary organs, and digestive tract.
largest collections found in ;
tonsils of the entrance of the throat,
Peters patches in the wall of the distal small intestine,
appendix in the large intestines
Describe the function of the thymus
functions as a lymphoid organ where T cells mature. ( no B cells are present here) . most active and latest in size during childhood. gradually gets smaller through adulthood