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what does a plateau in oxygen equilibrium mean
blood oxygen partial pressure sufficient to saturate blood hemoglobin
what allows for increased oxygen in blood
respiratory pigments
What respiratory pigments do chordates use
hemoglobin and myoglobin
where is myoglobin seen
muscle tissue
myoglobin structure
globin protein with heme pigment
heme group
iron based group attachment for oxygen
hemoglobin
tetrameric protein with 1 attachment per globin, specific specific
What happens to oxygen pressure when globins gets saturated
pressure increases
p50
pressure of oxygen when 50% oxygen bound to a transport protein
when is myoglobin best used
lower pressures because has a lower p50
What decreases affinity of oxygen to heme groups
increase of co2 to make blood acidic through carbonic acid and raised temperature
what does a flat slope on o2 vs. po2 graph mean
less metabollicaly demanding
when does embryonic hemoglobin become fetal hemoglobin and when does fetal hemoglobin become adult hemoglobin
after 3 months and 3 months post natal
why do you need a large SA
o2 exchange and rapid means of trnasport to tissues
circulatory system of vertebrates
closed system with pump, conduction vessels , capillaries
what is the heart used for
establish pressure gradient so that fluid will always flow down
characteristics of a heart
pulsatile compliance chambers, prominent back flow valves with endogenous rhythms
endogenous rhythms
heart dictates own beat
characteristic of conducting vessels
large radius for less resistance to create less work for the heart and thicker walls for less diffusion while in transport
order of conduction pathway vessel thickness
arterial wall, venous, capillary
Anastomosis functioin
direct blood flow and control blood tissue by opening or shutting
characteristics of capillary
small diameter and short, high resistance and short vessels needed or blood would not flow
what is resistance directly proportional and inversely to
length and radius^4
where is blood pressure the greatest
aorta and arteries
in what part of the conduction vessels is these the most resistance
arterioles because smaller and narrower
how are arterioles set compared to eachother and how does that impact their function
set in parallel and can change the flow through one but pressure difference is the same across the area
What muscles can change blood flow with contraction from chemical signals
smooth muscles
three regions of gut
hindgut, midgut, foregut
foregut function of digestive area
moves food and may start digestion
midgut function
acidic digestion and absorption
hindgut function
absorption of water and condense and removal of waste
foregut of human
oral pharynx and esophagus
midgut in humans
stomach and small intestine
hindgut in humans
large intestine and rectum
what does a bird have that is different from other GI tracts
crop in foregut
what does a fish have that is different from other GI tracts
pyloric ceca in midgut
mucosal layer function
lines lumen with epithelial cells
sub mucosal layer function
blood supply to gut
muscle layer in gut function
motility
adventitial layer function
connective tissue layer cover around GI tract
what allows for movement through mucosal layer
channel and carrier proteins and passive diffusion
channel protein
hydrophilic pore to let small ions pass and very selective
carrier protein
has a binding site with molecular shifts
coupled transport
movement up concentration gradient by moving molecules down a concentration gradient
simport
form of coupled transport where both molecules move in the same direction
what does the lumen epithelium have
absorptive enterocytes
what forms of transport are used in apical and basal of enterocytes
facilitated diffusion, active transport, bulk, simple diffusion
how is surface area in small intestine increased
mucossal villil and cellular microvilli which is villi for the villli
what does body size relate to in terms of the intestine
surface area of GI tract
do endotherms or ectotherms have a slightly higher surface area
endotherms
what is fermentation necessary for
process cellulose
qualities of fermentation
slow and temperature dependent
how does small intestine work
plug flow where food is coming in and product is moved out, and reactor uniform at any position
what does a decreased flow rate in a plug flow reactor
dramatic drop in reactant and increase in product (greater impact)
what would cause the rate of digestion to speed up
toxins not notified in stomach
where is the continuous flow/ stir model seen
stomach, rumen, saccular, large bowel
how does continuous flow work
components are always coming and removed while unchanged with a unidirectional flow, flow rate is impacted like plug flow
how do batch reactors work
components are move in, uniform mixing for reaction and products move out
foregut fermentors
cellulose is handled before it reaches the digestive and absorptive system
What kind of flow is the rumen in foregut fermentors
continuous flow reactor
what kind of food do foregut fermentors eat
low quality food
hindgut fermentors
cellulose handled after the small intestine
What kind of flow is the cecum in a hindgut fermentor
batch reactor
what kind of food do hindgut fermentors consume
high quality food with lower cellulose
What environment is the rumen in
anaerobic environment
Rumen functions
make volatile fatty acids and proteins
What does the rumen have for digestion
bacteria, archaea, fungi, protists
food breakdown equation
cellulose + microorganisms + NH3= more micro organisms + VFAs+ Co2 + CH4
VFA in order of production
acetate, propionate, butyrate, and others
Propionate function
synthesize glucose
saliva function
creates fluid environment for microorganisms
Why is urea cycled into saliva “urea recycling”
source of nitrogen for microorganisms growth and protein synthesis
Why is bicarbonate cycled into saliva
vfa production makes the rumen acidic which is buffered by bicarbonate
order of digestion for foregut fermentors
mouth - rumen -reticulum - omassum -abomassum - intestine
omassum function
prevents large groups of food from entering abomassum but allows microbes through
reticulum and rumen ph
5.5-7.5
how are volatile acids absorbed
through rumen wall
Abomasum
true stomach ph 1-2 for pepsin secreting
what kind of foregut for llama and sheep have
multichambered with a long small intestine attached