ch 1 - intro & signaling pathways

what does Wnt stand for in the Wnt signaling pathway?

wingless-related integration site

the hedgehog gene was first described within Drosophila, a ____, in 1980

fruit fly

in absence of hedgehog ligand, ____ protein works as the transcriptional repressor in SHH pathway

Gli3R

____ protein works as the transcriptional activator in SHH pathway

Gli2A

____ works as the transcriptional activator in Wnt pathway according to our lecture

β-Catenin

the hedgehog ligand receptor is called

Ptch

active Gli2A translocates into ____ within the cell for its target genes

nucleus

one of the hedgehog responsive target genes is called

cyclin D1