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Describe how the structure of an artery is adapted to its function 4.
Thick muscular walls withstand high blood pressure
Elastic fibres allow the artery to stretch and recoil
Small lumen maintains high pressure
Smooth inner lining reduces friction
Describe how the structure of a vein is adapted to its function 4.
Thin walls as blood pressure is low
Large lumen reduces resistance to blood flow
Valves prevent backflow of blood
Blood flow is helped by surrounding muscles
Explain how capillaries are adapted for efficient exchange 4.
Walls are one cell thick, reducing diffusion distance
Very narrow lumen slows blood flow
Extensive networks give a large surface area
Close contact with body cells increases diffusion rate
Compare arteries and veins 4.
Arteries carry blood away from the heart; veins carry blood towards the heart
Arteries have thick muscular walls; veins have thin walls
Arteries have a small lumen; veins have a large lumen
Veins contain valves; arteries do not
Explain why blood pressure is higher in arteries than veins 4.
Blood is pumped directly from the heart into arteries
Ventricular contraction generates high pressure
Pressure is lost as blood flows through capillaries
Veins are further from the heart
Describe the pathway of blood through the heart 6.
Blood enters the right atrium from the vena cava
Passes into the right ventricle
Pumped to the lungs via the pulmonary artery
Returns to the left atrium via the pulmonary vein
Passes into the left ventricle
Leaves the heart through the aorta
Explain the function of valves in the heart 4.
Prevent backflow of blood
Ensure blood flows in one direction
Open and close due to pressure changes
Maintain efficient circulation
Explain why the left ventricle has a thicker wall than the right ventricle 4.
Pumps blood to the entire body
Blood travels a greater distance
Higher pressure is required
Thicker muscle produces greater force
Describe the role of the septum in the heart 3.
Separates the left and right sides of the heart
Prevents mixing of oxygenated and deoxygenated blood
Maintains efficient oxygen delivery
Explain the importance of a double circulatory system 4.
Blood passes through the heart twice per cycle
Allows high pressure blood flow to the body
Increases the rate of oxygen delivery
Protects the lungs from high pressure
Compare pulmonary and systemic circulation 4.
Pulmonary circulation moves blood between the heart and lungs
Systemic circulation moves blood between the heart and the rest of the body
Pulmonary circulation operates at lower pressure
Systemic circulation operates at higher pressure
Describe what is meant by coronary heart disease 4.
Fatty deposits build up in coronary arteries
Arteries become narrowed
Blood flow to heart muscle is reduced
Oxygen supply decreases
Explain how coronary heart disease can cause a heart attack 4.
Plaque narrows coronary arteries
Blood flow to heart muscle is restricted
Oxygen supply becomes insufficient
Heart muscle cells die
Describe two risk factors for coronary heart disease and explain their effects 4.
Smoking damages artery walls and increases plaque formation
Diets high in saturated fat increase cholesterol levels
Lack of exercise can lead to obesity
Obesity increases blood pressure
Explain how smoking increases the risk of coronary heart disease 4.
Nicotine increases heart rate
Raises blood pressure
Carbon monoxide reduces oxygen transport
Artery walls are damaged
Explain how a high-fat diet increases the risk of coronary heart disease 4.
Increases blood cholesterol levels
Cholesterol deposits form plaques
Arteries become narrowed
Blood flow is reduced
Describe the benefits of regular exercise on the heart 4.
Strengthens the heart muscle
Lowers resting heart rate
Reduces blood pressure
Reduces risk of coronary heart disease
Explain how a stent is used to treat coronary heart disease 4.
Inserted into a narrowed coronary artery
Holds the artery open
Improves blood flow
Increases oxygen supply to the heart muscle
Explain how statins reduce the risk of coronary heart disease 4.
Lower blood cholesterol levels
Reduce plaque formation
Slow artery narrowing
Reduce the risk of blood clots
Compare stents and statins as treatments for coronary heart disease 4.
Stents give immediate improvement in blood flow
Statins act over a long period
Stents require surgery
Statins must be taken regularly
Explain why heart rate increases during exercise 4.
Muscles respire more
Oxygen demand increases
Heart pumps faster
Carbon dioxide is removed more quickly
Explain how red blood cells are adapted for oxygen transport 4.
Biconcave shape increases surface area
No nucleus allows more haemoglobin
Haemoglobin binds oxygen
Thin membrane shortens diffusion distance
Explain how white blood cells defend the body against disease 4.
Phagocytes engulf pathogens
Lymphocytes produce antibodies
Antibodies bind to antigens
Pathogens are destroyed
Explain the importance of platelets in the blood 4.
Cause blood clotting
Form a fibrin mesh
Prevent excessive blood loss
Reduce risk of infection
Explain why reduced blood flow is dangerous to the heart muscle 4.
Less oxygen is delivered
Aerobic respiration decreases
Less energy is released
Heart muscle cells may die