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What is osteogenesis imperfecta and it’s key features?
genetic in origin
Brittle bones, due to not enough collagen or abnormal collagen
Long bones may not grow at the same rate
marked scoliosis of the spine
What is Duchenne Muscular Dystrophy?
congenital muscle disorder
genetic in origin/most common type
Deficiency of a muscle protein called dystrophin
Diagnosis: High levels of serum creatinine from damaged muscle fibers
Present in both skeletal & cardiac muscles
Characterized by delayed motor development and muscle weakness
What is Paget’s disease and it’s key features?
osteitis deformans
acquired bone disorder
due to genetic & environmental factors
Rapid regeneration of bone in which the bone remains immature while entering the normal degeneration process
Immature bone is crudely structured and weak
Osteoarthritis (OA) , heart problems, bone cancer
What is osteoporosis and it’s complications and drugs related to it?
“lacy bones”; genetic
Progressive loss of bone mass
The greatest impact is in the spine
No cure; focuses on prevention
X-Ray, bone density scans (low dose) hips/spine
Treatment
Oral drugs to increase bone density to slow bone loss (bisphosphonates)
Fosamax
Boniva
what is gout?
acute inflammation of joints caused by kidney dysfunction or too much uric is produced by the body
Hot, red, and tender
Affects the big toe, can also affect ankles, wrist & hands
Occurs mainly in men 30-50
Diagnosis: blood for increased uric acid and creatinine
Treatment: allopurinol
What could be some dietary reasons someone get’s gout?
too much red meat, fructose, and beer
what is rhabdomyolysis?
(rhabdo) - acute muscle damage (can be life-threatening)
Release of protein byproduct of muscle damage by the - myoglobin
Causes
Extreme unconditioned exercise of exertion
Burns, heat stroke, or electrocution
Statins
Snakebites
Symptoms
Muscle weakness and soreness
Dark red urine
Nausea & vomiting
How is rhabdomyolysis diagnosed & treated?
Diagnosed
Lab test (urine) for myoglobin
Lab test (blood) for creatinine
Can look like coco-Cola
Result
Can lead to acute renal failure, possibly leading to death
Treatment
IV fluid resuscitation
Dialysis
What is osteomyelitis?
Infection in the bone
Usually begins as a superficial skin infection
Intermediate step before onset or gangrene
Can be caused by an infection with corresponding loss of circulation impairing healing
What is osteomyelitis associated with?
Associated with
Diabetes mellitus (DM)
Surgical infection
Postoperative fistula (abnormal connection between 2 organs)
What’s the surgical treatment for osteomyelitis?
Antibiotics (IV and oral)
Surgical debridement to clear necrotic tissue down to the viable bone
Use of rongeur and a curette
What is osteoarthritis as a disease?
degenerative condition of the joint from wear & tear
Chronic form of arthritis
Cartilage cushion between joints break down causing loss of lubrication and rubbing of bones together
Causes
Weight gain
Injury
Repetitive use
Genetics
Not “cracking” or “popping” joints
What are some surgical treatments for osteoarthritis?
Weight loss/exercise
Oral medications
NSAIDS
Opioid pain meds: Vicodin
Glucosamine chondroitin – supplement with questionable results
Steroid injections into the joint
Physical Therapy
What are the treatments and complications of osteoarthritis in the hip?
Surgical Treatment – permanent cure
Hip Replacement
Total hip arthroplasty with prosthetic device
Acetabulum and femur head
Partial hip arthroplasty with femoral component
Materials
Metal on metal (not used in US)
Metal on metal with polyethylene socket liner
Ceramic on metal
Ceramic on ceramic (not currently used)
Ceramic on metal with polyethylene socket liner
Cemented vs. press fit
Complications
Dislocation
Metal allergy
Leakage of metal fragments
What are neurostimulator devices?
failed back surgery syndrome
directs mild electrical impulses with pain messages to the brain
Spinal array and generator device
cervical nerve compression
More common in herniation and spondylosis
C4-C5 (shoulder and neck pain; loss of mobility)
C5-C6 (bicep, wrist, and thumb)
C6-C7 (triceps, forearm, and finger)
C7-T1 (hand grip weakness)
thoracic nerve compression
Upper back pain, abdominal pain, chest pain, lower body dysfunction
Can affect your breathing
Common in scoliosis and kyphosis
lumbar nerve compression
L1-L2 (most often anterior thigh and increase cases of cauda equina)
L2-L3 (pain in the anterior thigh)
L3-L4 (posterior thigh pain, lack of patellar reflex)
L4-L5 (calf and toes, inability to stand on toes; ankle will not support weight)
What are some chiropractic treatments?
Adjustments
Decompression
Heat therapy
Exercises
Steroid Injections (temporary)
laminectomy
Creates space by removing the lamina or back part of the vertebra
Spinal decompression surgery, usually for stenosis and spondylosis

diskectomy
Removes a portion of a herniated disk material which is pressuring the nerve root
Can accompany other spinal procedures
Minimally invasive
Can cause scar tissue – post laminectomy syndrome
Can cause loss of disk height and promote additional herniation in surrounding levels
spinal fusion
Fusing vertebral levels, so they form one bone
Loss of flexibility of the spine
bone grafting
Autograft from the patient’s own vertebra or iliac crest
Allograft from cadaver
Synthetic graft
plating systems
instrumentation
reinforces bone graft in the vertebra above and below
anterior interbody cages
instrumentation
made of titanium & inserted using an anterior approach
posterior interbody cages
instrumentation
made of titanium & inserted using a posterior approach

pedicle screw fixation
Instrumentation - surgical technique in spinal surgery
gripping vertebral segments to limit motion

types of fractures (matching section)
open (compound) - broken bone; open wound
closed - the bone is broken; the skin is intact
transverse - a fracture straight across the bone shaft
oblique - a fracture at an angle to the bone shaft
spiral - a fracture that twists around the bone shaft
comminuted - a fracture characterized by multiple fracture lines and bone pieces
greenstick - an incomplete fracture in which the bone is bent and only the outer curve of the bend is broken
compression - a fracture in which the bone is crushed or collapses into small pieces

closed reduction
treatment for fractures
Fracture manipulation and repositioning, and subsequent casting or splinting
Fracture repositioning with percutaneous pinning
Usually, for intra-articular fractures of the wrist, ankle, and elbow
Kirschner wires or K-wires, which are flexible
External fixator, which resembles a cage
ORIF (Open Reduction Internal Fixation)
treatment for fractures
Incision to gain access to the fracture site
Repositioning of the bone
Application of various appliances to hold the bone in place
Rods, plates, screws, nails
blunt force trauma
Velocity and force of impact contained damage
Hemorrhage into cavities and damage to critical organs determines mortality
Internal organs
Contusions
Rupture or laceration
Fractures
Treatment: symptomatic or surgical, blood transfusions
How is blunt force trauma diagnosed?
x-ray, ultrasound, CT scan, CBC, examining body fluids for blood
Blood loss and organ dysfunction may be immediate or delayed
Delayed effects may not have external visible signs of trauma
penetrating injury
Velocity and force of a projectile or implement, which breaks the skin and enters the cavity
May leave (retain) a foreign body, risk of infection
Blood loss and/or violation of a critical organ determines mortality
Laceration and/or accompanying compression damage
Do not remove foreign body. It’s preventing blood loss.
Symptoms
Obvious physical damage with penetration visible on x-ray
Treatment is usually surgical removal of foreign body and repair of internal damage; blood transfusions
Debridement, drainage, and/or evacuation of fragments and/or blood
laparotomy
surgical treatment for internal injuries
surgically opening the abdomen
thoracotomy
surgical treatment for internal injuries
surgically opening the chest cavity
craniotomy
surgical treatment for internal injuries
surgically opening the skull
amputation
Partial or complete separation of a limb or portion of a limb by a cut
Damage to bone, nerves, blood vessels, tissue, and skin of the stump
Reattachment (replantation) viability depends on time and the extent of damage
Viability in 6-8 hours if the detached part is cooled to prevent decomposition
Varies by body part and may be up to 24 hours if cooled
Viability is determined by tissue damage of both stumps
avulsion
Tearing or pulled away – gruesome injuries
a forcible separation or detachment such as a tearing away of a body part
Could include separation of limb without breaking the skin
What are the treatments of amputations and it’s complications?
Treatment
Debridement and freshening of the amputation stump
Sealing off blood vessels and preparing stump for grafting
Advancement flap graft (attached bed) or free graft to stump (donor site)
Complications
Infections of amputation stump
Non-healing graft due to comorbid conditions
Non-viable graft due to failure of revascularization
Phantom limb syndrome
What happens when your body parts are crushed?
Part of the body is squeezed between two objects
Massive tissue damage occurs, such as:
Fracture, soft tissue damage, skin damage
Compartment syndrome
Increased pressure in an arm or leg, which causes serious muscle, nerve, blood vessel, and tissue damage due to blunt force
Treatment: Surgical with potential surgical amputation
What are lacerations?
Open wounds
Full thickness disruption through the skin & deeper tissues underneath
Evidence of nerve damage - numbness at and distal to the site
Evidence of tendon damage - loss of control
Mortality depends on degree of blood loss from lacerated blood vessels
Risk of infection and development of cellulitis and gangrene
What is degrees of burns?
classified by the extent and severity of damage caused of the layers of skin affected
1st degree (superficial) burns
Affect only the outer layer of skin - epidermis.
The burn site is red, painful, dry, and with no blisters.
Mild sunburn is an example.
Long-term tissue damage is rare and often consists of an increase or decrease in the skin color

Second-degree (partial thickness) burns
Involve the epidermis and part of the lower layer of skin, the dermis. The burn site looks red, blistered, and may be swollen and painful

third-degree (full thickness) burns
Destroy the epidermis and dermis. They may go into the innermost layer of skin, the subcutaneous tissue. The burn site may look white or blackened and charred
fourth-degree (underlying tissue) burns
Go through both layers of the skin and underlying tissue as well as deeper tissue, possibly involving muscle, tendons, ligaments, and bone.
There is no feeling in the area since the nerve endings are destroyed
What are the body parts for rule of 9’s?
EMTs use this method of quickly estimate the body surface area of a burn
Head and Neck:
Upper Extremities: arm, forearm, hand
Torso: anterior and posterior
Lower Extremities: leg, thigh, lower leg, foot
Genital or Perineal Region: private areas
1. Know the complications and treatments for a 3rd degree burn
Treatment
Surgical debridement of necrotic tissue down to granulation tissue
Pealing or sloughing at a burn center
Skin grafting
Xenografts - fish skin
Fluid restoration for dehydration and kidney failure
Complications
Dehydration
Hypothermia
Thrombosis
Respiratory compromise
contusions
Bruising caused by broken capillaries
Acute inflammatory response, swelling, pain, immobility
Blood may gravitate to other areas, turn purple and yellow as blood is absorbed
Treatment: Tylenol, nothing with bleeding properties, rest, ice, compression, and elevation (RICE)
“I’ve fallen and I can’t get up”
Results in may 23- hour observations and potential for LTC
Immobility results in deconditioning in the elderly
abrasions
Rubs off the skin due to direct contact with rough surface
Skinned knee (“raspberries”)
Grazing an object
Continued rubbing or scratching
Friction burns
Floor/rug/carpet burn
Rope burn
Road rash
Treadmills
Minimal bleeding, but area scabs over and may form a scar
Treatment is topical
Covered with breathable gauze or non-stick bandage
Ointments to minimize risk of infection
minor sprain
acute inflammatory response, swelling, pain
Rest, Ice, Compression, elevation (RICE), and immobility/NSAIDS
major sprain & complications
acute inflammatory response, swelling pain
Rest, Ice, compression, elevation (RICE), and immobility/NSAIDS
Complications
Tearing, permanent weakening, arthritis
May require surgical intervention later
deep scar
scar formation
fibrotic area under the skin (bumpy) or depressed area
massage area to break up fibrotic tissue, so it can be absorbed
Can take months
May need dermatologist intervention
superficial
scar formation
keep soft with creams
massage area to prevent scar contracture
can take months to go away or may leave a permanent scar due to the destruction of pigment producing cells
dermatologist intervention
chemical peel
radiofrequency and ultrasonic directed therapies
What is some post surgical complications?
Shock - cardiogenic, septic, hypovolemic
Wound dehiscence - separation of wound edges (internal or external)
Infection - cellulitis (external) or abscess (internal)
Fistula - an abnormal connection between two tissues, often accompanied by infection
Mechanical Failure - complications from implanted devices (eroison, breakage, or leakage)
Hematoma/Seroma - encased accumulation of blood or fluid requiring drainage