Lecture 11 - Salt Forms
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5 Terms
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Excipients
Inactive ingredients that ensure drug product quality and performance
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Two primary classifications of stability
Physical, non-covalent changes to the product components
Chemical, changes to covalent bonding of the product components
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How can physical instability arise?
Changes in phase, i.e. soluble components becoming insoluble components
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How can physical instability manifest?
Precipitation, changes in pH may change drug solubility leading to this
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Buffers
A form of excipients that are designed to maintain the solution at at constant pH
Note 
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