18. Pathophysiological aspects of pregnancy 606

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How does the cardiac output change by the third trimester of physiological pregnancy?

Considerably increases around 40%

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How do the levels of blood pressure change after the second trimester of physiological pregnancy?

Decrease

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How does the GFR change in physiological pregnancy?

50% higher

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What is the main pathogenetical background of preeclampsia?

Disorder of placental circulation

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What can cause glycosuria in pregnancy?

  1. Hyperglycemia

  2. Increased GFR

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What are the consequences of non-treated gestational diabetes for newborn?

  1. Hypoglycemia

  2. High birth weight (macrosomia)

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  1. What are the characteristic symptoms of preeclampsia?

  1. Hypertension

  2. Massive proteinuria

  3. Severe edema(does not disappear by morning)

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What is the HELLP syndrome?

Hemolysis+Elevated Liver enzymes+Low Platelet count

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