Cancer
Abnormal cell growth caused by accumulation of mutations (TOO much division, NOT enough cell death)
Apoptosis
Cell death
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Cancer
Abnormal cell growth caused by accumulation of mutations (TOO much division, NOT enough cell death)
Apoptosis
Cell death
Pro
Mammagram
detects breast cancer
colonoscopy
detect colon cancer
tumor
a mass of cells with no function
malignant
cancerous tumor, spreads, life threatening
benign
not cancerous, removed easily, doesn’t spread
characteristics of cancer cells
immortal, lose contact inhibition, lose anchorage dependence
lose contact inhibition
doesn’t die when they come in contact with another cell
lose anchorage dependence
can grow anywhere and doesn’t need scaffold
carcinogen
causes mutation/cancer
Age
#1 risk factor for cancer
surgery
remove cancer
chemo
kills fast reproducing cells (ALL)
radiation
kills cancer cells
immunotherapy
uses immune system to kill cancer
precision meds
personal
Genetics of cancer
ALL is genetic, but not all is inherited
Proto-oncogenes
controls normal cell division (good)
onco
cancer
oncogene
mutated proto-oncogene
tumor suppressor gene (TSG)
prevents uncontrolled cell growth
Increased risk genes
BRAC1 + BRAC2
Cell division
Growth, repair, and replace
Chromatin
Uncondensed DNA in its natural state
Diploid
Body cell (2n)
Haploid
Reproductive cell (n)
Interphase
G1, S, and G2
Mitosis
DNA/nucleus divide
Cytokinesis
Cytoplasm divides
Karyotype
An individuals complete set of chromosomes
Chromosome
Condensed DNA for division
Meiosis
Making gametes
Gametes
Egg and sperm
Oogenesis
Process of making eggs
Spermatogenesis
Process of making sperm
Sexual reproduction
Creates genetic variation
External reproduction
Egg + speem meet outside (in environment)
Internal reproduction
Fertilization occurs within female
Testicle
Male gonad. Produce sperm and testosterone
Scrotum
Sack of skin and tissue. For support and body temp regulation
Epididymis
Where sperm is stored. Learns to swim and fertilize
Vas deferns
Pair of ducts carrying sperm from testis to outside
Urethra
Carries pee and sperm from urinary bladder to exterior
Penis
Contains terminal part of urethra.
Prostate gland
Largest semen secreting gland. Secretes alkaline fluid. Prevents sperm from sticking together
Male hormone
Testosterone
Ovaries
Female gonad. Eggs produced
Oviduct
Fallopian tube. Joins ovaries and uterus. Fertiltion is here.
Ectopic pregnancy
Embryo grows in oviduct
Uterus
Where embreyo implants
Endometrium
Uterus lining
Cervix
Narrow neck of uterus, holds baby in, HPV
Vagina
Tube. Birth canal.
Estrogen
Produced by ovary. Growth of egg.
Progesterone
Corpus luteum. Prevents ovulation
Hormones
FSH: follicle stimulant hormone. Pituitary gland. Develops follicles. LH: luteinizing hormone. Stimulated ovulation. Pituatary gland
Pregnancy
40 weeks. Gestation based on size.
Fetus
8 weeks
Oxytocin
Starts labor