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What is a major cellular source of ROS?
Aerobic metabolism in mitochondria
How are ROS produced during mitochondrial respiration?
By incomplete reduction of oxygen in the electron transport chain
What is the respiratory burst?
Deliberate production of high levels of ROS by immune cells
Which enzyme complex produces ROS in the respiratory burst?
The NADPH oxidase complex
Which cells perform the respiratory burst?
Phagocytes
What is the function of ROS in the respiratory burst?
Antimicrobial defence to kill microbes