Cardiovascualr meds:HMG-CoA Reductase Inhibitors (statins): atorvastatin

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6 Terms

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atorvastatin moa

  • Decrease LDL and VLDL

  • Increased HDL

  • Vasodilation, decrease in plaque site inflammation

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use

  • Hypercholesterolemia

  • Protection against MI and stroke in clients with DM

  • Prevention of coronary events

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Complications:


  • Hepatotoxicity

  • Myopathy (muscle pain)

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Contraindications:

  • Pregnancy and breastfeeding

  • Liver disorder

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Drug/drug Interactions:

  • Fibrates and ezetimibe

  • Erythromycin

  • Amiodarone

  • Grapefruit juice

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Nursing Education:

  • PO with pm meal as cholesterol is synthesized during the night

  • Obtain baseline cholesterol tests & monitor throughout treatment

  • Lifestyle adjustment

  • Do not consume alcohol