PODI14009: Rheumatology and Musculoskeletal Medicine in Podiatry

Define Arthritis

When joints are painful, stiff and swolllen

Define Muskuloskeletal Conditions

Conditions which affect bones, muscles, tendons, ligaments as well as joints

SSefine autoimmune disease

Conditions where the musculoskeletal system as well as other parts of the body, including the eyes, skin, internal organs and the nervous system can be inflammed

List modifiable risk factros which can attribute to the devleopement of musculoskeletal conditions

1. overweight and obesity

2. occupational hazards

3. tabacco use

List the barriers included in the Immune system

1. skin

2. mucous membranes

3. sebum

What are leukocytes and what do they do

1. White blood cells and they are natural killer cells that kill everything

What is the roll of T-lymphocytes (T-Cells)

identify and destroy infected, cancerous, or foreign cells

What are the roles of B-lymphocytes (lymphocyte)

1. to differentiate into plasma cells to produce antibodies

2. Memory B cells - remeber pathogens to undertake a robust response if detected again

What is the role of macrophage cells

To detect, engulf, and destroy pathogens, cellular debris, and foreign substances via phagocytosis

What is the role of basophil cells

to release chemicals which initiate the immune response

What is the role of Eosinophil cells

to break down the chemcial produced by basophil cells

What is the role of neutrophils

to act as the first line defence by rapidly migrating to pathogenic sites to kill pathogens via phagocytosis