Med Chem II: General Anesthetic Agents
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16 Terms
Atropine
Anticholinergic Oral pre-anesthetic agent
used to decrease motility and decrease bronchial secretions
Diazepam/Phenbarbital
Hypno-sedatives used as an oral pre-anesthetic agents to relieve anxiety and nervousness
Morphine
Analgesic used as an oral pre-anesthetic agent to subside pain
Succinylcholine chloride
Neuromuscular blocker used to relax skeletal muscles
Thiopental sodium: IV induction anesthetic agent
barbiturate derivative: S fast acting lipophillic
Ketamine HCl: IV induction anesthetic agent: basic
ketone and amine.. blocks glutamate receptors: NMDA antagonist very powerful centrally acting analgesic
no hypnotic activity
Etomidate: IV induction anesthetic agent: basic nature but solubilized with propylene glycol and ethanol
ester, imidazole, benzene: GABA potentiation
Midazolam HCl: IV induction anesthetic agent
sedation, muscle relaxant: GABA potentiation
Propofol: IV induction anesthetic agent
phenol + 2 isopropyl: administered as an emulsion with soya oil & glycerol: GABA potentiation: induces sleep/hypnosis
Clonidine: IV induction anesthetic agent: alpha 2 agonist
decreases sympathetic outflow given intrathecal to suppress sympathetic reflexes: NOT ANALGESIC
Gamma-hydroxy-butyric acid: IV induction anesthetic agent
not commonly used: bio-isostere of GABA: sodium salt
direct GABA and dopamine agonist
Nitrous Oxide: Inhalation (Volatile Gas) anesthetic agent
very powerful central analgesic: laughing gas hypoxia
Diethyl Ether: Inhalation (Volatile Gas) anesthetic agent
volatile liquid: not used anymore for humans: flammable
2 ethyl connected by an ether
Halothane: Inhalation (Volatile Gas) anesthetic agent
volatile liquid nonflammable: hepatotoxic liver hates halogens: hypnotic effect: 2 C, 3F, Cl, Br replace hydrogens
methoxyfluorane: Inhalation (Volatile Gas) anesthetic agent
volataile liquid somewhat flammable: analgesic and muscle relaxant: NO hypnotic effect: O-demethylation
ether function = NO hypnotic effect:
Sevofluorane: Inhalation (volatile gas) anesthetic agent
analgesic and muscle relaxant: NO hypnotic effect:
ether function = NO hypnotic effect:
Note 
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