Single Nucleotide Polymorphism and Data Analysis of Population Genetics
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7 Terms
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What are SNP’s
Single nucleotide polymorphisms
Substitution of a single nucleotide
Substitution of a single nucleotide
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What percentage must a substitution mutation be in order to be a SNP
Affect greater than 1% of the population
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How often do SNP’s occur
Once in every 300 nucleotides
10 million in human genome
10 million in human genome
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Why are SNP’s biological markers
Used to locate genes associated with disease
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What can SNP’s predict
Response to certain drugs
Susceptibility to environmental factors
Risk of developing particular diseases
Susceptibility to environmental factors
Risk of developing particular diseases
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Haplotype map
HapMap catalogue of common SNP’s
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What is the HapMap used for
carries out genome-wide association studies (GWAS)